(PDF) Narcolepsy with cataplexy and Parkinson's disease. Case Report
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Narcolepsy is a rare sleeping disorder, but for those who have it, it affects quality of life
Narcolepsy Sleep Attack and Cataplexy Attack 30 year old Graduate Student
Marguerite Smith Patient Case Study for World Haemochromatosis Week 2018
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PDF Case Study of a Narcoleptic Patient with a Family History of Narcolepsy
Case Study of a Narcoleptic Patient with a Family History of Narcolepsy Narcolepsy is characterized by excessive daytime sleepiness, and this is typically associated with cataplexy and other rapid eye movement (REM) sleep phenomena such as sleep paralysis and hypnagogic hallucinations. These narcoleptic symptoms have been occasionally misdia-
Case #2: 29-Year-Old Male With Type 2 Narcolepsy
EP: 6. Case #1: 18-Year-Old Female With Type 1 Narcolepsy. EP: 7. Case #2: 29-Year-Old Male With Type 2 Narcolepsy. EP: 8. Practice Pearls for Narcolepsy Management. Richard K. Bogan, MD, FCCP, FAASM: I'm going to throw another case at you. We've got a 29-year-old male project manager who presents with excessive sleepiness.
Living with Narcolepsy: Current Management Strategies, Future Prospects
Case studies indicate that cataplexy treatments may be effective in reducing orgasmolepsy for some patients, but rigorous studies in this area have not been pursued.107 A further consideration, which receives little mention in the literature, is the potential impact of other symptoms of narcolepsy and narcolepsy treatments on intimate ...
Case report of narcolepsy in a six-year-old child initially
Summary. This report describes a case of first-onset narcolepsy in a six-year-old female that was misdiagnosed as atypical epilepsy and other diagnoses at eight different hospitals over a period of 10 months before the correct diagnosis was made. The diagnosis of narcolepsy is more difficult in children because very few of them experience all ...
Awakened Hope for Narcolepsy
Published September 13, 2023. N Engl J Med 2023;389: e21. DOI: 10.1056/NEJMp2308308. VOL. 389 NO. 11. Audio Interview. Awakened Hope for Narcolepsy — ITT Episode 17 32m 35s Download. In this ...
Recent advances in treatment for narcolepsy
Other attempts to use such therapies in narcoleptic patients were since reported, but they are all uncontrolled case studies, with very small numbers of patients. We reported and summarized those studies and their results in a recent review. 22 A list of immune-based therapies that were tested in human narcolepsy is presented in Table 3. Those ...
Case study of a narcoleptic patient with a family history of narcolepsy
An ongoing study of the genetics of narcolepsy ascertains families through a case series of narcoleptic probands using diagnostic criteria consisting of 1) clinical history of excessive somnolence ...
A practical guide to the pharmacological and behavioral therapy of
In particular, it is possible to help narcoleptic patients to identify and improve dysfunctional cognitions, enhance treatment adherence, take medications at the appropriate times, maintain good sleep hygiene, and take scheduled naps to address the psychosocial needs of such patients. ... In any case, an actigraphic study with NT1 children and ...
Narcolepsy treatment: pharmacological and behavioral strategies in
Only a few studies [44,45,46] demonstrated significant differences in the ability of staying awake and active in narcoleptic patients compared with control subjects. Remarkable is the effect on sleepiness, evident within few days even at the lowest dosage (10 mg); however, a higher dose up to 60 can be used to reach a clinically meaningful ...
Case study of a narcoleptic patient with a family history of narcolepsy
Case study of a narcoleptic patient with a family history of narcolepsy. Yoon Kyung Shin, Seung Chul Hong, Youn Jung Cho, Jong Hyun Jeong, Jin Hee ... (REM) sleep phenomena such as sleep paralysis and hypnagogic hallucinations. These narcoleptic symptoms have been occasionally misdiagnosed as depression, seizure or even schizophrenia. The ...
Narcolepsy
N Engl J Med 2015;373: 2654 - 2662. DOI: 10.1056/NEJMra1500587. VOL. 373 NO. 27. Narcolepsy, one of the most common causes of chronic sleepiness, affects about 1 in 2000 people. Despite the ...
Effective treatment of narcolepsy-like symptoms with high ...
3 Discussion. To the best of our knowledge, this is the first case report that high-frequency rTMS over the left DLPFC is possibly effective for narcolepsy-like symptoms. In this case, the patient experienced 25 sessions of 10 Hz magnetic stimulation with its intensity at 80% resting motor threshold. Throughout the treatment, this young patient ...
Case Study of a Narcoleptic Patient with a Family History of Narcolepsy
The female patient introduced here had experienced excessive daytime sleepiness, severe cataplexy and sleep paralysis, however, she didn't know the cause of her symptoms in spite of having visited hospitals several times for five years. Narcolepsy is characterized by excessive daytime sleepiness, and this is typically associated with cataplexy and other rapid eye movement (REM) sleep ...
Narcolepsy
Narcolepsy is a sleep disorder that makes people very drowsy during the day. People with narcolepsy find it hard to stay awake for long periods of time. They fall asleep suddenly. This can cause serious problems in their daily routine. Sometimes narcolepsy also causes a sudden loss of muscle tone, known as cataplexy (KAT-uh-plek-see).
Perioperative risks of narcolepsy in patients undergoing general
This study used a retrospective case-control design that assessed potential factors associated with morbidity and mortality and anesthetic complications in narcoleptic patients undergoing general anesthesia. The institutional medical database from January 1, 2011, through September 30, 2015, was electronically searched to identify patients with ...
A mutation in a case of early onset narcolepsy and a generalized
We included all patients with a family history or lacking HLA-DQB1 * 0602 from our database of more than 500 narcoleptic patients. Fourteen polymorphisms were found among 74 Caucasian patients and ...
Day case general anaesthesia in a patient with narcolepsy
We report a case of day surgery under general anaesthesia involving a narcoleptic patient, who was receiving modafinil treatment. Case report. A 28-year-old woman with an 11 year history of narcolepsy presented at the day surgery unit for an elective hysteroscopy and polypectomy under general anaesthesia.
Recognizing the Symptom Spectrum of Narcolepsy to Improve Timely
In young narcoleptic patients, SDB seems to be a rare condition and if present, very mild. Restless Legs Syndrome (RLS)62-64: RLS in narcolepsy type 1 shows a higher prevalence compared to the general population. However, the picture is often milder, and with a more equal sex distribution. ... a nationwide population-based case control study.
Listening to the Patient Voice in Narcolepsy: Diagnostic Delay, Disease
Diagnostic delay in narcolepsy is an important clinical problem because it can result in misdiagnosis, inappropriate medication exposure, and/or delayed treatment and can result in impaired productivity, poor academic performance, and safety concerns such as drowsy driving. 5 Furthermore, early diagnosis close to symptom onset may become ...
Schizophrenia and narcolepsy: A review with a case report
A case series shows that outcomes in these patients vary. 17,21 A study shows that long-term use of psychostimulants (methamphetamine), as occurs in the treatment of narcolepsy, can cause long-standing reduction of dopamine transporter density in the brain, even if psychostimulants use ceases. 22 This can be associated with the development of ...
Patient-Reported Measures of Narcolepsy: The Need for Better Assessment
An additional study again compared these three measures for prediction of narcolepsy in 80 patients with narcolepsy/cataplexy and 111 patients with EDS due to various non-narcoleptic sleep disorders. 48 This study reported sensitivity and specificity for the SNS (score less than zero) of 89% and 88%, whereas the UNS (score of 14 or higher) had ...
Case Study of a Narcoleptic Patient with a Family History of Narcolepsy
Case Study of a Narcoleptic Patient with a Family History of Narcolepsy. Abstract. Narcolepsy is characterized by excessive daytime sleepiness, and this is typically associated with cataplexy and other rapid eye movement (REM) sleep phenomena such as sleep paralysis and hypnagogic hallucinations. These narcoleptic symptoms have been ...
Long-Term Use of Oral Corticosteroids and Safety Outcomes for Patients
Findings In this nested case-control study including 1 025 270 patients with atopic dermatitis, use of oral corticosteroids for more than 90 days during 1 year was associated with a slightly increased risk of composite adverse outcomes. There was no increased risk with use of oral corticosteroids for more than 30 days.
relationship between person-centred care and well-being and
The main aim of this study was to assess the relationship between PCC and the physical and social well-being of patients living with obesity, as well as their satisfaction with care. This study is based on a cross-sectional, web-based survey administered among a representative panel of Dutch individuals living with obesity.
Narcolepsy-related nightmares: a distinct type of nightmares in need of
Dear Editor, Nightmares are a common yet overlooked symptom of narcolepsy. Although frequent nightmares (generally defined as occurring at least once per week) are experienced by an estimated 4%-5% of the adult population [1, 2], studies have demonstrated elevated rates in narcolepsy ranging from 29% to 41.5% [].In the largest study to date which included 419 individuals with narcolepsy (220 ...
Diversity in gut microbiota among colorectal cancer patients: findings
2.1 Study design. This was a case-control study, and participants were prospectively enrolled between March 23 and August 26, 2021.Fecal samples were collected from colorectal cancer patients and a control group in the gastroenterology department at Charles Nicolle Hospital of Tunis, then transported to the Microbiology laboratory where they were immediately aliquoted and frozen at −80 °C ...
Diagnosis of hepatic encephalopathy (HE) with a Case Study
The panel uses a case study to discuss identifying and diagnosing HE and some considerations of patient-specific characteristics. EP: 1 . Epidemiology and Trends in Hepatic Encephalopathy (HE) in ...
New case study shows patients who shop around could save thousands in
The study found a self-pay patient could save more than $150,000 and an insured patient could save more than $2,800 on total knee replacement surgery. "When hospitals provide easy-to-find prices, patients can make financially informed decisions about planned surgeries and treatments," said Patricia Kelmar, TexPIRG Education Fund's senior ...
Long COVID symptoms and demographic associations: A retrospective case
The long-term effects of COVID-19 are still being studied, and the incidence rate of LC may change over time. In the UK, studies have explored LC symptoms and risk factors in non-hospitalised individuals using primary care records 4 and consolidated evidence on persistent symptoms and their associations in broader populations. 5 Additionally, there has been significant interest in Patient ...
Naloxone and Patient Outcomes in Out-of-Hospital Cardiac Arrests in
In this retrospective cohort study of adult patients with OHCA treated in 3 Northern California counties between 2015 and 2023, EMS administration of naloxone was associated with an 11.8-percentage point absolute increase in ROSC and a 3.9-percentage point absolute increase in patient survival to hospital discharge.
IMAGES
VIDEO
COMMENTS
Case Study of a Narcoleptic Patient with a Family History of Narcolepsy Narcolepsy is characterized by excessive daytime sleepiness, and this is typically associated with cataplexy and other rapid eye movement (REM) sleep phenomena such as sleep paralysis and hypnagogic hallucinations. These narcoleptic symptoms have been occasionally misdia-
EP: 6. Case #1: 18-Year-Old Female With Type 1 Narcolepsy. EP: 7. Case #2: 29-Year-Old Male With Type 2 Narcolepsy. EP: 8. Practice Pearls for Narcolepsy Management. Richard K. Bogan, MD, FCCP, FAASM: I'm going to throw another case at you. We've got a 29-year-old male project manager who presents with excessive sleepiness.
Case studies indicate that cataplexy treatments may be effective in reducing orgasmolepsy for some patients, but rigorous studies in this area have not been pursued.107 A further consideration, which receives little mention in the literature, is the potential impact of other symptoms of narcolepsy and narcolepsy treatments on intimate ...
Summary. This report describes a case of first-onset narcolepsy in a six-year-old female that was misdiagnosed as atypical epilepsy and other diagnoses at eight different hospitals over a period of 10 months before the correct diagnosis was made. The diagnosis of narcolepsy is more difficult in children because very few of them experience all ...
Published September 13, 2023. N Engl J Med 2023;389: e21. DOI: 10.1056/NEJMp2308308. VOL. 389 NO. 11. Audio Interview. Awakened Hope for Narcolepsy — ITT Episode 17 32m 35s Download. In this ...
Other attempts to use such therapies in narcoleptic patients were since reported, but they are all uncontrolled case studies, with very small numbers of patients. We reported and summarized those studies and their results in a recent review. 22 A list of immune-based therapies that were tested in human narcolepsy is presented in Table 3. Those ...
An ongoing study of the genetics of narcolepsy ascertains families through a case series of narcoleptic probands using diagnostic criteria consisting of 1) clinical history of excessive somnolence ...
In particular, it is possible to help narcoleptic patients to identify and improve dysfunctional cognitions, enhance treatment adherence, take medications at the appropriate times, maintain good sleep hygiene, and take scheduled naps to address the psychosocial needs of such patients. ... In any case, an actigraphic study with NT1 children and ...
Only a few studies [44,45,46] demonstrated significant differences in the ability of staying awake and active in narcoleptic patients compared with control subjects. Remarkable is the effect on sleepiness, evident within few days even at the lowest dosage (10 mg); however, a higher dose up to 60 can be used to reach a clinically meaningful ...
Case study of a narcoleptic patient with a family history of narcolepsy. Yoon Kyung Shin, Seung Chul Hong, Youn Jung Cho, Jong Hyun Jeong, Jin Hee ... (REM) sleep phenomena such as sleep paralysis and hypnagogic hallucinations. These narcoleptic symptoms have been occasionally misdiagnosed as depression, seizure or even schizophrenia. The ...
N Engl J Med 2015;373: 2654 - 2662. DOI: 10.1056/NEJMra1500587. VOL. 373 NO. 27. Narcolepsy, one of the most common causes of chronic sleepiness, affects about 1 in 2000 people. Despite the ...
3 Discussion. To the best of our knowledge, this is the first case report that high-frequency rTMS over the left DLPFC is possibly effective for narcolepsy-like symptoms. In this case, the patient experienced 25 sessions of 10 Hz magnetic stimulation with its intensity at 80% resting motor threshold. Throughout the treatment, this young patient ...
The female patient introduced here had experienced excessive daytime sleepiness, severe cataplexy and sleep paralysis, however, she didn't know the cause of her symptoms in spite of having visited hospitals several times for five years. Narcolepsy is characterized by excessive daytime sleepiness, and this is typically associated with cataplexy and other rapid eye movement (REM) sleep ...
Narcolepsy is a sleep disorder that makes people very drowsy during the day. People with narcolepsy find it hard to stay awake for long periods of time. They fall asleep suddenly. This can cause serious problems in their daily routine. Sometimes narcolepsy also causes a sudden loss of muscle tone, known as cataplexy (KAT-uh-plek-see).
This study used a retrospective case-control design that assessed potential factors associated with morbidity and mortality and anesthetic complications in narcoleptic patients undergoing general anesthesia. The institutional medical database from January 1, 2011, through September 30, 2015, was electronically searched to identify patients with ...
We included all patients with a family history or lacking HLA-DQB1 * 0602 from our database of more than 500 narcoleptic patients. Fourteen polymorphisms were found among 74 Caucasian patients and ...
We report a case of day surgery under general anaesthesia involving a narcoleptic patient, who was receiving modafinil treatment. Case report. A 28-year-old woman with an 11 year history of narcolepsy presented at the day surgery unit for an elective hysteroscopy and polypectomy under general anaesthesia.
In young narcoleptic patients, SDB seems to be a rare condition and if present, very mild. Restless Legs Syndrome (RLS)62-64: RLS in narcolepsy type 1 shows a higher prevalence compared to the general population. However, the picture is often milder, and with a more equal sex distribution. ... a nationwide population-based case control study.
Diagnostic delay in narcolepsy is an important clinical problem because it can result in misdiagnosis, inappropriate medication exposure, and/or delayed treatment and can result in impaired productivity, poor academic performance, and safety concerns such as drowsy driving. 5 Furthermore, early diagnosis close to symptom onset may become ...
A case series shows that outcomes in these patients vary. 17,21 A study shows that long-term use of psychostimulants (methamphetamine), as occurs in the treatment of narcolepsy, can cause long-standing reduction of dopamine transporter density in the brain, even if psychostimulants use ceases. 22 This can be associated with the development of ...
An additional study again compared these three measures for prediction of narcolepsy in 80 patients with narcolepsy/cataplexy and 111 patients with EDS due to various non-narcoleptic sleep disorders. 48 This study reported sensitivity and specificity for the SNS (score less than zero) of 89% and 88%, whereas the UNS (score of 14 or higher) had ...
Case Study of a Narcoleptic Patient with a Family History of Narcolepsy. Abstract. Narcolepsy is characterized by excessive daytime sleepiness, and this is typically associated with cataplexy and other rapid eye movement (REM) sleep phenomena such as sleep paralysis and hypnagogic hallucinations. These narcoleptic symptoms have been ...
Findings In this nested case-control study including 1 025 270 patients with atopic dermatitis, use of oral corticosteroids for more than 90 days during 1 year was associated with a slightly increased risk of composite adverse outcomes. There was no increased risk with use of oral corticosteroids for more than 30 days.
The main aim of this study was to assess the relationship between PCC and the physical and social well-being of patients living with obesity, as well as their satisfaction with care. This study is based on a cross-sectional, web-based survey administered among a representative panel of Dutch individuals living with obesity.
Dear Editor, Nightmares are a common yet overlooked symptom of narcolepsy. Although frequent nightmares (generally defined as occurring at least once per week) are experienced by an estimated 4%-5% of the adult population [1, 2], studies have demonstrated elevated rates in narcolepsy ranging from 29% to 41.5% [].In the largest study to date which included 419 individuals with narcolepsy (220 ...
2.1 Study design. This was a case-control study, and participants were prospectively enrolled between March 23 and August 26, 2021.Fecal samples were collected from colorectal cancer patients and a control group in the gastroenterology department at Charles Nicolle Hospital of Tunis, then transported to the Microbiology laboratory where they were immediately aliquoted and frozen at −80 °C ...
The panel uses a case study to discuss identifying and diagnosing HE and some considerations of patient-specific characteristics. EP: 1 . Epidemiology and Trends in Hepatic Encephalopathy (HE) in ...
The study found a self-pay patient could save more than $150,000 and an insured patient could save more than $2,800 on total knee replacement surgery. "When hospitals provide easy-to-find prices, patients can make financially informed decisions about planned surgeries and treatments," said Patricia Kelmar, TexPIRG Education Fund's senior ...
The long-term effects of COVID-19 are still being studied, and the incidence rate of LC may change over time. In the UK, studies have explored LC symptoms and risk factors in non-hospitalised individuals using primary care records 4 and consolidated evidence on persistent symptoms and their associations in broader populations. 5 Additionally, there has been significant interest in Patient ...
In this retrospective cohort study of adult patients with OHCA treated in 3 Northern California counties between 2015 and 2023, EMS administration of naloxone was associated with an 11.8-percentage point absolute increase in ROSC and a 3.9-percentage point absolute increase in patient survival to hospital discharge.