200+ Biotechnology Research Topics: Let’s Shape the Future
In the dynamic landscape of scientific exploration, biotechnology stands at the forefront, revolutionizing the way we approach healthcare, agriculture, and environmental sustainability. This interdisciplinary field encompasses a vast array of research topics that hold the potential to reshape our world.
In this blog post, we will delve into the realm of biotechnology research topics, understanding their significance and exploring the diverse avenues that researchers are actively investigating.
Overview of Biotechnology Research
Table of Contents
Biotechnology, at its core, involves the application of biological systems, organisms, or derivatives to develop technologies and products for the benefit of humanity.
The scope of biotechnology research is broad, covering areas such as genetic engineering, biomedical engineering, environmental biotechnology, and industrial biotechnology. Its interdisciplinary nature makes it a melting pot of ideas and innovations, pushing the boundaries of what is possible.
Unlock your academic potential with expert . Our experienced professionals are here to guide you, ensuring top-notch quality and timely submissions. Don’t let academic stress hold you back – excel with confidence! |
How to Select The Best Biotechnology Research Topics?
- Identify Your Interests
Start by reflecting on your own interests within the broad field of biotechnology. What aspects of biotechnology excite you the most? Identifying your passion will make the research process more engaging.
- Stay Informed About Current Trends
Keep up with the latest developments and trends in biotechnology. Subscribe to scientific journals, attend conferences, and follow reputable websites to stay informed about cutting-edge research. This will help you identify gaps in knowledge or areas where advancements are needed.
- Consider Societal Impact
Evaluate the potential societal impact of your chosen research topic. How does it contribute to solving real-world problems? Biotechnology has applications in healthcare, agriculture, environmental conservation, and more. Choose a topic that aligns with the broader goal of improving quality of life or addressing global challenges.
- Assess Feasibility and Resources
Evaluate the feasibility of your research topic. Consider the availability of resources, including laboratory equipment, funding, and expertise. A well-defined and achievable research plan will increase the likelihood of successful outcomes.
- Explore Innovation Opportunities
Look for opportunities to contribute to innovation within the field. Consider topics that push the boundaries of current knowledge, introduce novel methodologies, or explore interdisciplinary approaches. Innovation often leads to groundbreaking discoveries.
- Consult with Mentors and Peers
Seek guidance from mentors, professors, or colleagues who have expertise in biotechnology. Discuss your research interests with them and gather insights. They can provide valuable advice on the feasibility and significance of your chosen topic.
- Balance Specificity and Breadth
Strike a balance between biotechnology research topics that are specific enough to address a particular aspect of biotechnology and broad enough to allow for meaningful research. A topic that is too narrow may limit your research scope, while one that is too broad may lack focus.
- Consider Ethical Implications
Be mindful of the ethical implications of your research. Biotechnology, especially areas like genetic engineering, can raise ethical concerns. Ensure that your chosen topic aligns with ethical standards and consider how your research may impact society.
- Evaluate Industry Relevance
Consider the relevance of your research topic to the biotechnology industry. Industry-relevant research has the potential for practical applications and may attract funding and collaboration opportunities.
- Stay Flexible and Open-Minded
Be open to refining or adjusting your research topic as you delve deeper into the literature and gather more information. Flexibility is key to adapting to new insights and developments in the field.
200+ Biotechnology Research Topics: Category-Wise
Genetic engineering.
- CRISPR-Cas9: Recent Advances and Applications
- Gene Editing for Therapeutic Purposes: Opportunities and Challenges
- Precision Medicine and Personalized Genomic Therapies
- Genome Sequencing Technologies: Current State and Future Prospects
- Synthetic Biology: Engineering New Life Forms
- Genetic Modification of Crops for Improved Yield and Resistance
- Ethical Considerations in Human Genetic Engineering
- Gene Therapy for Neurological Disorders
- Epigenetics: Understanding the Role of Gene Regulation
- CRISPR in Agriculture: Enhancing Crop Traits
Biomedical Engineering
- Tissue Engineering: Creating Organs in the Lab
- 3D Printing in Biomedical Applications
- Advances in Drug Delivery Systems
- Nanotechnology in Medicine: Theranostic Approaches
- Bioinformatics and Computational Biology in Biomedicine
- Wearable Biomedical Devices for Health Monitoring
- Stem Cell Research and Regenerative Medicine
- Precision Oncology: Tailoring Cancer Treatments
- Biomaterials for Biomedical Applications
- Biomechanics in Biomedical Engineering
Environmental Biotechnology
- Bioremediation of Polluted Environments
- Waste-to-Energy Technologies: Turning Trash into Power
- Sustainable Agriculture Practices Using Biotechnology
- Bioaugmentation in Wastewater Treatment
- Microbial Fuel Cells: Harnessing Microorganisms for Energy
- Biotechnology in Conservation Biology
- Phytoremediation: Plants as Environmental Cleanup Agents
- Aquaponics: Integration of Aquaculture and Hydroponics
- Biodiversity Monitoring Using DNA Barcoding
- Algal Biofuels: A Sustainable Energy Source
Industrial Biotechnology
- Enzyme Engineering for Industrial Applications
- Bioprocessing and Bio-manufacturing Innovations
- Industrial Applications of Microbial Biotechnology
- Bio-based Materials: Eco-friendly Alternatives
- Synthetic Biology for Industrial Processes
- Metabolic Engineering for Chemical Production
- Industrial Fermentation: Optimization and Scale-up
- Biocatalysis in Pharmaceutical Industry
- Advanced Bioprocess Monitoring and Control
- Green Chemistry: Sustainable Practices in Industry
Emerging Trends in Biotechnology
- CRISPR-Based Diagnostics: A New Era in Disease Detection
- Neurobiotechnology: Advancements in Brain-Computer Interfaces
- Advances in Nanotechnology for Healthcare
- Computational Biology: Modeling Biological Systems
- Organoids: Miniature Organs for Drug Testing
- Genome Editing in Non-Human Organisms
- Biotechnology and the Internet of Things (IoT)
- Exosome-based Therapeutics: Potential Applications
- Biohybrid Systems: Integrating Living and Artificial Components
- Metagenomics: Exploring Microbial Communities
Ethical and Social Implications
- Ethical Considerations in CRISPR-Based Gene Editing
- Privacy Concerns in Personal Genomic Data Sharing
- Biotechnology and Social Equity: Bridging the Gap
- Dual-Use Dilemmas in Biotechnological Research
- Informed Consent in Genetic Testing and Research
- Accessibility of Biotechnological Therapies: Global Perspectives
- Human Enhancement Technologies: Ethical Perspectives
- Biotechnology and Cultural Perspectives on Genetic Modification
- Social Impact Assessment of Biotechnological Interventions
- Intellectual Property Rights in Biotechnology
Computational Biology and Bioinformatics
- Machine Learning in Biomedical Data Analysis
- Network Biology: Understanding Biological Systems
- Structural Bioinformatics: Predicting Protein Structures
- Data Mining in Genomics and Proteomics
- Systems Biology Approaches in Biotechnology
- Comparative Genomics: Evolutionary Insights
- Bioinformatics Tools for Drug Discovery
- Cloud Computing in Biomedical Research
- Artificial Intelligence in Diagnostics and Treatment
- Computational Approaches to Vaccine Design
Health and Medicine
- Vaccines and Immunotherapy: Advancements in Disease Prevention
- CRISPR-Based Therapies for Genetic Disorders
- Infectious Disease Diagnostics Using Biotechnology
- Telemedicine and Biotechnology Integration
- Biotechnology in Rare Disease Research
- Gut Microbiome and Human Health
- Precision Nutrition: Personalized Diets Using Biotechnology
- Biotechnology Approaches to Combat Antibiotic Resistance
- Point-of-Care Diagnostics for Global Health
- Biotechnology in Aging Research and Longevity
Agricultural Biotechnology
- CRISPR and Gene Editing in Crop Improvement
- Precision Agriculture: Integrating Technology for Crop Management
- Biotechnology Solutions for Food Security
- RNA Interference in Pest Control
- Vertical Farming and Biotechnology
- Plant-Microbe Interactions for Sustainable Agriculture
- Biofortification: Enhancing Nutritional Content in Crops
- Smart Farming Technologies and Biotechnology
- Precision Livestock Farming Using Biotechnological Tools
- Drought-Tolerant Crops: Biotechnological Approaches
Biotechnology and Education
- Integrating Biotechnology into STEM Education
- Virtual Labs in Biotechnology Teaching
- Biotechnology Outreach Programs for Schools
- Online Courses in Biotechnology: Accessibility and Quality
- Hands-on Biotechnology Experiments for Students
- Bioethics Education in Biotechnology Programs
- Role of Internships in Biotechnology Education
- Collaborative Learning in Biotechnology Classrooms
- Biotechnology Education for Non-Science Majors
- Addressing Gender Disparities in Biotechnology Education
Funding and Policy
- Government Funding Initiatives for Biotechnology Research
- Private Sector Investment in Biotechnology Ventures
- Impact of Intellectual Property Policies on Biotechnology
- Ethical Guidelines for Biotechnological Research
- Public-Private Partnerships in Biotechnology
- Regulatory Frameworks for Gene Editing Technologies
- Biotechnology and Global Health Policy
- Biotechnology Diplomacy: International Collaboration
- Funding Challenges in Biotechnology Startups
- Role of Nonprofit Organizations in Biotechnological Research
Biotechnology and the Environment
- Biotechnology for Air Pollution Control
- Microbial Sensors for Environmental Monitoring
- Remote Sensing in Environmental Biotechnology
- Climate Change Mitigation Using Biotechnology
- Circular Economy and Biotechnological Innovations
- Marine Biotechnology for Ocean Conservation
- Bio-inspired Design for Environmental Solutions
- Ecological Restoration Using Biotechnological Approaches
- Impact of Biotechnology on Biodiversity
- Biotechnology and Sustainable Urban Development
Biosecurity and Biosafety
- Biosecurity Measures in Biotechnology Laboratories
- Dual-Use Research and Ethical Considerations
- Global Collaboration for Biosafety in Biotechnology
- Security Risks in Gene Editing Technologies
- Surveillance Technologies in Biotechnological Research
- Biosecurity Education for Biotechnology Professionals
- Risk Assessment in Biotechnology Research
- Bioethics in Biodefense Research
- Biotechnology and National Security
- Public Awareness and Biosecurity in Biotechnology
Industry Applications
- Biotechnology in the Pharmaceutical Industry
- Bioprocessing Innovations for Drug Production
- Industrial Enzymes and Their Applications
- Biotechnology in Food and Beverage Production
- Applications of Synthetic Biology in Industry
- Biotechnology in Textile Manufacturing
- Cosmetic and Personal Care Biotechnology
- Biotechnological Approaches in Renewable Energy
- Advanced Materials Production Using Biotechnology
- Biotechnology in the Automotive Industry
Miscellaneous Topics
- DNA Barcoding in Species Identification
- Bioart: The Intersection of Biology and Art
- Biotechnology in Forensic Science
- Using Biotechnology to Preserve Cultural Heritage
- Biohacking: DIY Biology and Citizen Science
- Microbiome Engineering for Human Health
- Environmental DNA (eDNA) for Biodiversity Monitoring
- Biotechnology and Astrobiology: Searching for Life Beyond Earth
- Biotechnology and Sports Science
- Biotechnology and the Future of Space Exploration
Challenges and Ethical Considerations in Biotechnology Research
As biotechnology continues to advance, it brings forth a set of challenges and ethical considerations. Biosecurity concerns, especially in the context of gene editing technologies, raise questions about the responsible use of powerful tools like CRISPR.
Ethical implications of genetic manipulation, such as the creation of designer babies, demand careful consideration and international collaboration to establish guidelines and regulations.
Moreover, the environmental and social impact of biotechnological interventions must be thoroughly assessed to ensure responsible and sustainable practices.
Funding and Resources for Biotechnology Research
The pursuit of biotechnology research topics requires substantial funding and resources. Government grants and funding agencies play a pivotal role in supporting research initiatives.
Simultaneously, the private sector, including biotechnology companies and venture capitalists, invest in promising projects. Collaboration and partnerships between academia, industry, and nonprofit organizations further amplify the impact of biotechnological research.
Future Prospects of Biotechnology Research
As we look to the future, the integration of biotechnology with other scientific disciplines holds immense potential. Collaborations with fields like artificial intelligence, materials science, and robotics may lead to unprecedented breakthroughs.
The development of innovative technologies and their application to global health and sustainability challenges will likely shape the future of biotechnology.
In conclusion, biotechnology research is a dynamic and transformative force with the potential to revolutionize multiple facets of our lives. The exploration of diverse biotechnology research topics, from genetic engineering to emerging trends like synthetic biology and nanobiotechnology, highlights the breadth of possibilities within this field.
However, researchers must navigate challenges and ethical considerations to ensure that biotechnological advancements are used responsibly for the betterment of society.
With continued funding, collaboration, and a commitment to ethical practices, the future of biotechnology research holds exciting promise, propelling us towards a more sustainable and technologically advanced world.
Related Posts
Step by Step Guide on The Best Way to Finance Car
The Best Way on How to Get Fund For Business to Grow it Efficiently
- Google Meet
- Mobile Dialer
Resent Search
Management Assignment Writing
Technical Assignment Writing
Finance Assignment Writing
Medical Nursing Writing
Resume Writing
Civil engineering writing
Mathematics and Statistics Projects
CV Writing Service
Essay Writing Service
Online Dissertation Help
Thesis Writing Help
RESEARCH PAPER WRITING SERVICE
Case Study Writing Service
Electrical Engineering Assignment Help
IT Assignment Help
Mechanical Engineering Assignment Help
Homework Writing Help
Science Assignment Writing
Arts Architecture Assignment Help
Chemical Engineering Assignment Help
Computer Network Assignment Help
Arts Assignment Help
Coursework Writing Help
Custom Paper Writing Services
Personal Statement Writing
Biotechnology Assignment Help
C Programming Assignment Help
English Essay Writing
MATLAB Assignment Help
Narrative Writing Help
Report Writing Help
Get Top Quality Assignment Assistance
Online Exam Help
Macroeconomics Homework Help
Change Management Assignment Help
Operation management Assignment Help
Strategy Assignment Help
Human Resource Management Assignment Help
Psychology Assignment Writing Help
Algebra Homework Help
Best Assignment Writing Tips
Statistics Homework Help
CDR Writing Services
TAFE Assignment Help
Auditing Assignment Help
Literature Essay Help
Online University Assignment Writing
Economics Assignment Help
Programming Language Assignment Help
Political Science Assignment Help
Marketing Assignment Help
Project Management Assignment Help
Geography Assignment Help
Do My Assignment For Me
Business Ethics Assignment Help
Pricing Strategy Assignment Help
The Best Taxation Assignment Help
Finance Planning Assignment Help
Solve My Accounting Paper Online
Market Analysis Assignment
4p Marketing Assignment Help
Corporate Strategy Assignment Help
Project Risk Management Assignment Help
Environmental Law Assignment Help
History Assignment Help
Geometry Assignment Help
Physics Assignment Help
Clinical Reasoning Cycle
Forex Assignment Help
Python Assignment Help
Behavioural Finance Assignment Help
PHP Assignment Help
Social Science Assignment Help
Capital Budgeting Assignment Help
Trigonometry Assignment Help
Java Programming Assignment Help
Corporate Finance Planning Help
Sports Science Assignment Help
Accounting For Financial Statements Assignment Help
Robotics Assignment Help
Cost Accounting Assignment Help
Business Accounting Assignment Help
Activity Based Accounting Assignment Help
Econometrics Assignment Help
Managerial Accounting Assignment Help
R Studio Assignment Help
Cookery Assignment Help
Solidworks assignment Help
UML Diagram Assignment Help
Data Flow Diagram Assignment Help
Employment Law Assignment Help
Calculus Assignment Help
Arithmetic Assignment Help
Write My Assignment
Business Intelligence Assignment Help
Database Assignment Help
Fluid Mechanics Assignment Help
Web Design Assignment Help
Student Assignment Help
Online CPM Homework Help
Chemistry Assignment Help
Biology Assignment Help
Corporate Governance Law Assignment Help
Auto CAD Assignment Help
Public Relations Assignment Help
Bioinformatics Assignment Help
Engineering Assignment Help
Computer Science Assignment Help
Aerospace Engineering Assignment Help
Finance Assignment Help
Conflict Management Assignment Help
Paleontology Assignment Help
Commercial Law Assignment Help
Criminal Law Assignment Help
Anthropology Assignment Help
Biochemistry Assignment Help
Get the best cheap assignment Help
Urgent Assignment Help
Paying For Assignment Help
HND Assignment Help
Legitimate Essay Writing Help
Best Online Proofreading Services
Need Help With Your Academic Assignment
Assignment Writing Help In Canada
Assignment Writing Help In UAE
Online Assignment Writing Help in the USA
Assignment Writing Help In Australia
Assignment Writing Help In the UK
Scholarship Essay Writing Help
University of Huddersfield Assignment Help
Ph.D. Assignment Writing Help
Law Assignment Writing Help
Website Design and Development Assignment Help
University of Greenwich Assignment Assistance in the UK
University of Warwick Assignment Writing Help
Academic Counselling Sessions
Academic Counselling and Sample Service
Professional Proofreading Services
Technical Assistance
Counseling Sample & Proofreading
Agroecology Assignment Help
MBA Assignment Help
Coventry University Assignment Writing Help
Online Pharmacology Assignment Help
C++ Programming Assignment Help
University of Nottingham Assignment Writing Help
Research Proposal Topics In Biotechnology
Biotechnology is a fascinating subject that blends biology and technology and provides a huge chance to develop new ideas. However, before pursuing a career in this field, a person needs to complete a number of studies and have a thorough knowledge of the matter. When we begin our career must we conduct study to discover some innovative innovations that could benefit people around the world. Biotechnology is one of a variety of sciences of life, including pharmacy. Students who are pursuing graduation, post-graduation or PhD must complete the research work and compose their thesis to earn the satisfaction in their education. When choosing a subject for biotechnology-related research it is important to choose one that is likely to inspire us. Based on our passion and personal preferences, the subject to study may differ.
What is Biotechnology?
In its most basic sense, biotechnology is the science of biology that enables technology Biotechnology harnesses the power of the biomolecular and cellular processes to create products and technologies that enhance our lives and the wellbeing of the planet. Biotechnology has been utilizing microorganisms' biological processes for over six thousand years to create useful food items like cheese and bread as well as to keep dairy products in good condition.
Modern biotechnology has created breakthrough products and technology to treat rare and debilitating illnesses help reduce our footprint on the environment and feed hungry people, consume less energy and use less and provide safer, more clean and productive industrial production processes.
Introduction
Biotechnology is credited with groundbreaking advancements in technological development and development of products to create sustainable and cleaner world. This is in large part due to biotechnology that we've made progress toward the creation of more efficient industrial manufacturing bases. Additionally, it assists in the creation of greener energy, feeding more hungry people and not leaving a large environmental footprint, and helping humanity fight rare and fatal diseases.
Our writing services for assignments within the field of biotechnology covers all kinds of subjects that are designed to test and validate the skills of students prior to awarding their certificates. We assist students to successfully complete their course in all kinds of biotechnology-related courses. This includes biological sciences for medical use (red) and eco-biotechnology (green) marine biotechnology (blue) and industrial biotechnology (white).
What do we hope to gain from all these Initiatives?
Our primary goal in preparing this list of the top 100 biotechnology assignment subjects is to aid students in deciding on effective time management techniques. We've witnessed a large amount of cases where when looking for online help with assignments with the topic, examining sources of information, and citing the correct order of reference students find themselves stuck at various points. In the majority of cases, students have difficulty even to get through their dilemma of choosing a topic. This is why we contribute in our effort to help make the process easier for students in biotech quickly and efficiently. Our students are able to save time and energy in order to help them make use of the time they are given to write the assignment with the most appropriate topics.
Let's look at some of the newest areas of biotechnology research and the related areas.
- Renewable Energy Technology Management Promoting Village
- Molasses is a molasses-based ingredient that can be used to produce and the treatment of its effluent
- Different ways to evapotranspirate
- Scattering Parameters of Circulator Bio-Technology
- Renewable Energy Technology Management Promoting Village.
Structural Biology of Infectious Diseases
A variety of studies are being conducted into the techniques used by pathogens in order to infect humans and other species and for designing strategies for countering the disease. The main areas that are available to study by biotech researchers include:
- inlA from Listeria monocytogenes when combined with E-cadherin from humans.
- InlC in Listeria monocytogenes that are multipart with human Tuba.
- Phospholipase PatA of Legionella pnemophila.
- The inactivation process of mammalian TLR2 by inhibiting antibody.
- There are many proteins that come originate from Mycobacterium tuberculosis.
Plant Biotechnology
Another significant area for research in biotechnology for plants is to study the genetic causes of the plant's responses to scarcity and salinity, which have a significant impact on yields of the crop and food.
- Recognition and classification of genes that influence the responses of plants to drought and salinity.
- A component of small-signing molecules in plants' responses to salinity and drought.
- Genetic enhancement of plant sensitivity salinity and drought.
Pharmacogenetics
It's also a significant area for conducting research in biotechnology. One of the most important reasons for doing so could be the identification of various genetic factors that cause differences in drug effectiveness and susceptibility for adverse reactions. Some of the subjects which can be studied are,
- Pharmacogenomics of Drug Transporters
- Pharmacogenomics of Metformin's response to type II mellitus
- The pharmacogenomics behind anti-hypertensive medicines
- The Pharmacogenomics of anti-cancer drugs
Forensic DNA
A further area of research in biotechnology research is the study of the genetic diversity of humans for its applications in criminal justice. Some of the topics that could be studied include,
- Y-chromosome Forensic Kit, Development of commercial prototype.
- Genetic testing of Indels in African populations.
- The Y-chromosome genotyping process is used for African populations.
- Study of paternal and maternal ancestry of mixed communities in South Africa.
- The study of the local diversity in genetics using highly mutating Y-STRs and Indels.
- South African Innocence Project: The study of DNA extracted from historical crime scene.
- Nanotechnology is a new technology that can be applied to DNA genotyping.
- Nanotechnology methods to isolate DNA.
Food Biotechnology
It is possible to conduct research in order to create innovative methods and processes in the fields of food processing and water. The most fascinating topics include:
- A molecular-based technology that allows for the rapid identification and detection of foodborne pathogens in intricate food chains.
- The effects of conventional and modern processing techniques on the bacteria that are associated with Aspalathus lineriasis.
- DNA-based identification of species of animals that are present in meat products that are sold raw.
- The phage assay and PCR are used to detect and limit the spread of foodborne pathogens.
- Retention and elimination of pathogenic, heat-resistant and other microorganisms that are treated by UV-C.
- Analysis of an F1 generation of the cross Bon Rouge x Packham's Triumph by Simple Sequence Repeat (SSR/microsatellite).
- The identification of heavy metal tolerant and sensitive genotypes
- Identification of genes that are involved in tolerance to heavy metals
- The isolation of novel growth-promoting bacteria that can help crops cope with heavy metal stress . Identification of proteins that signal lipids to increase the tolerance of plants to stress from heavy metals
This topic includes high-resolution protein expression profiling for the investigation of proteome profiles. The following are a few of the most fascinating topics:
- The identification and profile of stress-responsive proteins that respond to abiotic stress in Arabidopsis Thalian and Sorghum bicolor.
- Analyzing sugar biosynthesis-related proteins in Sorghum bicolor, and study of their roles in drought stress tolerance
- Evaluation of the viability and long-term sustainability of Sweet Sorghum for bioethanol (and other by-products) production in South Africa
- In the direction of developing an environmentally sustainable, low-tech hypoallergenic latex Agroprocessing System designed specifically especially for South African small-holder farmers.
Bioinformatics
This is an additional aspect of biotechnology research. The current trend is to discover new methods to combat cancer. Bioinformatics may help identify proteins and genes as well as their role in the fight against cancer. Check out some of the areas that are suitable to study.
- Prediction of anticancer peptides with HIMMER and the the support vector machine.
- The identification and verification of innovative therapeutic antimicrobial peptides for Human Immunodeficiency Virus In the lab and molecular method.
- The identification of biomarkers that are associated with cancer of the ovary using an molecular and in-silico method.
- Biomarkers identified in breast cancer, as possible therapeutic and diagnostic agents with a combination of molecular and in-silico approaches.
- The identification of MiRNA's as biomarkers for screening of cancerous prostates in the early stages an in-silico and molecular method
- Identification of putatively identified the genes present in breast cancer tissues as biomarkers for early detection of lobular and ductal breast cancers.
- Examining the significance of Retinoblastoma Binding Protein 6 (RBBP6) in the regulation of the cancer-related protein Y-Box Binding Protein 1 (YB-1).
- Examining the role played by Retinoblastoma Binding Protein 6 (RBBP6) in the regulation of the cancer suppressor p53 through Mouse Double Minute 2 (MDM2).
- Structural analysis of the anti-oxidant properties of the 1-Cys peroxiredoxin Prx2 found in the plant that resurrects itself Xerophyta viscosa.
Nanotechnology
This is a fascinating aspect of biotechnology, which can be used to identify effective tools to address the most serious health issues.
- Evaluation of cancer-specific peptides to determine their applications for the detection of cancer.
- The development of a quantum dot-based detection systems for breast cancer.
- The creation of targeted Nano-constructs for in vivo imaging as well as the treatment of tumors.
- Novel quinone compounds are being tested as anti-cancer medicines.
- Embedelin is delivered to malignant cells in a specific manner.
- The anti-cancer activities of Tulbaghia Violacea extracts were studied biochemically .
- Novel organic compounds are screened for their anti-cancer potential.
- To treat HIV, nanotechnology-based therapeutic techniques are being developed.
Top 100 Biotechnology Research Proposal Topics to Consider in 2022
We've prepared a list of the top 100 most suggested dissertation topics, which were compiled by our experts in research. They've made sure to offer a an extensive list of topics that cover all aspects of the topic. We hope that this list will meet all of the requirements for assistance with your dissertation . Let us start with our list of subjects, one at a time each one
- Achieving effective control of renewable power technologies to help the village
- The production of ethanol through the aid of molasses and the treatment of its effluent
- Different approaches and aspects of Evapotranspiration
- Its scattering parameter is biotechnology circulator
- The inactivation of mammalian TLR2 via an inhibiting antibody
- The number of proteins produced by Mycobacterium tuberculosis
- Recognition and classification of genes that shape the responses of plants to drought and salinity.
- The small sign molecules that are involved in the response that plants have to the effects of salinity as well as drought
- Genetic improvement of the plant's sensitivity to drought and saltiness
- The pharmacogenomics of drug transporters
- The anti-cancer drugs' pharmacogenomics are based on pharmac
- The pharmacogenomics of antihypertensive medications
- Indels genotyping of African populations
- Genomics of the Y-chromosomes of African populations
- The profiling of DNA extracted from historical crime scenes Consider the implications of South African Innocence Project
- Nanotechnology-related methods for DNA isolation
- Nanotechnology applications in the context of DNA genotyping
- Recognizing the heavy metals that are tolerant with genotypes that are sensitive.
- Genetic characteristics that play a role within the procedure of gaining tolerance to metals
- The animal's DNA is authenticated by the species by the commercial production of raw meat products
- The use of molecular-based technology is in the sense of detection and identification of foodborne pathogens in complicated food systems
- Assessing the effectiveness of cancer-specific peptides that are suitable for efficient implementations in the area of diagnosis and treatment for cancer
- Quantum Dot-based detection system is being developed in relation to a positive breast cancer diagnosis
- It is targeted delivery of the embelin to cancerous cells
- Exploring the potential of novel quinone compounds as anti-cancer agents
- Treatment strategies for treating HIV in addition to the significance of nanotechnology the treatment of HIV.
- A review of the medicinal value the antioxidants found in nature.
- An in-depth examination of the structure of COVID spike proteins
- A review of the immune response to the stem therapy using cells
- CRISPR-Cas9 technology to aid in the process of editing the genome
- Tissue engineering and delivery of drugs through the application of Chitosan
- Evaluation of beneficial effects of cancer vaccines
- Use of PacBio sequencing in relation to genome assembly of model organisms
- Examining the connection between mRNA suppression and its effect on the growth of stem cells
- Biomimicry is a method of identifying of cancer cells
- The sub-classification and characterisation of the Yellow enzymes
- The process of producing food products that are hypoallergenic and fermented.
- The production of hypoallergenic milk
- The purification process for the thermostable phytase
- Bioconversion of the cellulose produce products that are significant for industry
- The investigation of the gut microbiota of the model organisms
- The use of fungal enzymes for the manufacture of chemical glue
- A look at those inhibitors to exocellulase as well as endocellulase
- Examine the value of microorganisms to aid in the recovery of gas from shale.
- Examine the thorough analysis of the method of natural decomposition
- Examine ways to recycle bio-wastes
- Improved bio-remediation in the case of oil spills
- The process of gold biosorption is accomplished with the aid of the cyanobacterium
- A healthy equilibrium between the biotic and the abiotic elements by using biotechnological devices
- The measurement of the mercury level in fish by means of markers
- Exploring the biotechnological capabilities from Jellyfish related microbiomes Jellyfish related microbiome
- What is the role of marine fungi to aid in attempts to break down plastics and polymers?
- Examine the biotechnological possibilities that can be extracted of dinoflagellates
- Removing endosulfan residues using the use of biotechnology the agriculture sector
- The creation of the ELISA method for the detection of crop virus
- Enhancing the quality of drinking water by the aid of the E.coli consortium
- The characterisation of E.coli is its isolation from the feces of Zoo animals
- Enhancing the resistance of crops to the attack of insects
- The reduction of the expenditure on agriculture by using efficient bio-tools
- Are there the most efficient ways to stop erosion of soils using the help of biotechnology-based tools?
- What can biotechnology do to assist in increasing the levels of vitamin content in GM food items?
- Enhancing the distribution of pesticides by using biotechnology
- Comparing the biofortification of folate in various types of corpses
- Examine the photovoltaic-based generation of ocean-based crop
- What is the best way to use nanotechnology will improve the efficiency of the agriculture sector?
- Analyzing the mechanisms that govern resistance to water stresses in models of plants
- Production and testing of human immune boosters within the test organisms
- Comparing genomic analysis to the usefulness of tools intended for bioinformatics
- The Arabinogalactan protein sequence and its value in the field of computational methods
- Analyzing and interpreting gut microbiota from model organisms
- Different methods of purification of proteins A comparative analysis
- The diagnosis of microbes and their function in micro-arrays of oligonucleotide oligonu
- The use of diverse techniques within the biomedical research field that includes micro-arrays technology
- The use of microbial community to produce the greenhouse effect
- Evaluation of the computational properties of various proteins that are derived from the marine microbiota
- E.coli gene mapping through the help of different tools for microbial research
- Intensifying the strains of Cyanobacterium the aid of gene sequencing
- Assessment and description by computation of crystallized proteins that are found in the natural world.
- MTERF protein and the use of it to end the process of transcription that occurs in mitochondrial DNA inside algae
- Reverse column chromatography in phase and its use in the separation of proteins
- The study of the various proteins that are found within Mycobacterium leprae.
- A review of the methods that are ideal to ensure the success of cloning RNA
- Examine the most common mistakes of biotechnology in conserving the ecology and natural environment.
- Is there a method to ensure that the medicinal plants are free of insects? Discuss
- What are the dangers caused by pest resistant animals on birds and human beings?
- What are the many areas of biotechnology that remain unexplored in terms research?
- What's the future of biotechnology in the medical field?
- Recombinant DNA technology to develop of new medical treatments
- What is the reason for the type of bacteria that is used to make vaccines with the aid of biotechnology?
- How can biotechnology aid in the development of new medicines that are resistant to the mutations of viruses and bacteria?
- Is there a long-term treatment for cancer that is available in the near term? Biotechnology could play an essential role in this?
- What is the reason it is so important that students remember the DNA codes in biotechnology?
- How can we create hybrid seeds with assistance of biotechnology?
- How can one create resistant plants to pests and what are the benefits of these seeds in final yields in agriculture?
- Examine bio-magnification and its effects on the ecology
- What are the causes to the reasons ecologists do not approve the use of pest-resistant seed, even though they are in application in agriculture?
- How has biotechnology influenced the lives of farmers in developing countries?
- Biotechnology can be used to boost the yield of plant species?
- Examine the role played by biotechnology to increase the production of the seasonal crops
- Are there any adverse side effects associated with pharmaceutical drugs when they are manufactured with biotechnological techniques? Let the issue with real-world examples
We attempted to cover the essential topics needed for research work. Other topics are available that could be picked based on our interests, the facilities available and resources available for the research, as well as resources and time limits.
We have reached the end of this list. We feel it was beneficial in satisfying the selection criteria. Furthermore, the inclusion of biotechnology-related assignment themes was done in such a manner that they may help us with the requirements of assignment writing kinds and forms. The themes listed above can meet our demands for topic selection linked to aid with case studies and essay assistance, research paper writing help , or thesis writing help .
Frequently asked questions
What are some biotechnology research proposal topics .
Some of biotechnology topics are:
What are the research areas in biotechnology ?
What is best topic for research in biotechnology , what are some examples of biotechnology , what is the scope of biotechnology , what is master in biotechnology , is biotechnology a high paying job , is biotechnology hard to study , is biotechnology a good career , which agecy is best for biotechnology assignment help , can a biotechnologist become a doctor , is biotechnology better than microbiology , is b tech biotechnology a good course .
Generic Conventions: Assignment Help Services
Research Paper Topics For Medical
Top 5 Resources for Writing Excellent Academic Assignments
How to Write a Literature Review for Academic Purposes
Tips for Writing a killer introduction to your assignment
How To Write A Compelling Conclusion For Your University Assignment
Research Papers Topics For Social Science
Best 150 New Research Paper Ideas For Students
7 Best Plagiarism Checkers for Students And Teachers in 2024
Research Topics for Marketing
Enquiry form.
Thank you for visiting nature.com. You are using a browser version with limited support for CSS. To obtain the best experience, we recommend you use a more up to date browser (or turn off compatibility mode in Internet Explorer). In the meantime, to ensure continued support, we are displaying the site without styles and JavaScript.
- View all journals
Plant biotechnology articles from across Nature Portfolio
Plant biotechnology can be defined as the introduction of desirable traits into plants through genetic modification.
Related Subjects
- Agricultural genetics
- Field trials
- Molecular engineering in plants
Latest Research and Reviews
Exploratory analysis of agro-morphological characteristics in Nigella sativa L. plant genotypes to determine mutagen colchicine ameliorative/ non-ameliorative impacts
- Shweta Verma
- Manisha Hariwal
- Sanjay Kumar
Intelligent agricultural robotic detection system for greenhouse tomato leaf diseases using soft computing techniques and deep learning
- Thi Thoa Mac
- Tien-Duc Nguyen
- Xuan-Thuan Nguyen
T2T genome assemblies of Fallopia multiflora (Heshouwu) and F. multiflora var. angulata
- Shaohua Zeng
- Changjuan Mo
Elucidation of Spartina dimethylsulfoniopropionate synthesis genes enables engineering of stress tolerant plants
Invasive Spartina grasses accumulate high levels of intracellular dimethylsulfoniopropionate (DMSP). Here, the authors report the isolation and characterization of the genes involved in DMSP biosynthesis and show that administration of DMSP by root uptake or overexpression of the DMSP biosynthesis genes results in salinity and drought tolerance in Arabidopsis.
- Rocky D. Payet
- Lorelei J. Bilham
- J. Benjamin Miller
Critical yield components for achieving high annual grain yield in ratoon rice
- Linqiong Song
- Qiyuan Tang
Multifaceted natural drought response mechanisms in three elite date palm cultivars uncovered by expressed sequence tags analysis
- Zafar Iqbal
- Muhammad Munir
News and Comment
The global patent landscape of functional food innovation
An analysis of patent documents reveals a trend of increasing interest in functional food innovations that may aid future decision-making in research, business and policymaking.
- Maima Matin
- Dalibor Hrg
- Atanas G. Atanasov
Printed electronics for cultivating plants in space
Plants are vital to future long-term space missions as a renewable food source and ecological system for producing essential substances. NASA has been developing special chambers to grow fresh vegetables in space, and printed electronics may be the key to monitoring the health and growth of these plants with minimal human effort, resources and energy.
- Siqing Wang
Smart gene, smart canopy
No transgene needed
- Guillaume Tena
Generation and analysis of the rice proteome reveals a role for m 6 A in posttranscriptional regulation
We present a comprehensive quantitative analysis of the proteome across 14 major rice tissues, which reveals that N 6 -methyladenosine (m 6 A) is negatively correlated with protein abundance. This finding provides insight into the longstanding discrepancy observed between RNA and protein levels in plants.
Synthetic moss
Technological advances have demonstrated the possibility of chemical synthesis of a multicellular plant genome. What does this mean for humans and how should we prepare for this breakthrough?
Quick links
- Explore articles by subject
- Guide to authors
- Editorial policies
MINI REVIEW article
Nanotechnology in plant science: to make a long story short.
- 1 Faculty of Engineering and the Environment, University of Southampton, Southampton, United Kingdom
- 2 Department of Pharmacy, University of Salerno, Fisciano, Italy
This mini-review aims at gaining knowledge on basic aspects of plant nanotechnology. While in recent years the enormous progress of nanotechnology in biomedical sciences has revolutionized therapeutic and diagnostic approaches, the comprehension of nanoparticle-plant interactions, including uptake, mobilization and accumulation, is still in its infancy. Deeper studies are needed to establish the impact of nanomaterials (NMs) on plant growth and agro-ecosystems and to develop smart nanotechnology applications in crop improvement. Herein we provide a short overview of NMs employed in plant science and concisely describe key NM-plant interactions in terms of uptake, mobilization mechanisms, and biological effects. The major current applications in plants are reviewed also discussing the potential use of polymeric soft NMs which may open new and safer opportunities for smart delivery of biomolecules and for new strategies in plant genetic engineering, with the final aim to enhance plant defense and/or stimulate plant growth and development and, ultimately, crop production. Finally, we envisage that multidisciplinary collaborative approaches will be central to fill the knowledge gap in plant nanotechnology and push toward the use of NMs in agriculture and, more in general, in plant science research.
Introduction
Nanomaterials have unique physicochemical properties and provide versatile scaffolds for functionalization with biomolecules. Moreover, certain NMs such as gold and magnetic nanoparticles as well as polymeric or hybrid NMs have shown to respond to external stimuli achieving a spatiotemporal controlled release of macromolecules. For these reasons, over the last two decades, engineered nanomaterials have been successfully tested and applied in medicine and pharmacology, especially for diagnostic or therapeutic purposes ( Bruchez et al., 1998 ; Tang et al., 2006 ; Perrault et al., 2009 ). More recently, the field of nanotechnology is gaining an increased interest in plant science, especially for the application of nanomaterials (NMs) as vehicles of agrochemicals or biomolecules in plants, and the great potential to enhance crop productivity ( Khan et al., 2017 ).
It is reasonable to argue that the potentiality and the benefits of the application of NMs in plant sciences and agriculture are still not fully exploited, due to some bottlenecks, which can be briefly summarized as follows: (i) the need to design and synthesis safe NMs which do not interfere negatively with plant growth and development ( Sabo-Attwood et al., 2012 ); (ii) the lack of knowledge on the exact mechanisms of NMs uptake and mobilization in plants ( Ranjan et al., 2017 ) and, (iii) the lack of multidisciplinary approaches, necessary for the design and the implementation of nanotechnology applications in plants.
Nanomaterials in Plant Science
According to ASTM standards, Nanomaterials (NMs) can be defined as natural or manufactured materials, typically ranging between 1 and100 nm ( Astm E2456 - 06 , 2012 ). NMs have a small size and a high surface-to-volume ratio, which confer to them remarkable chemical and physical properties in comparison to their bulk counterparts ( Roduner, 2006 ). NMs have unique and versatile physicochemical properties, which makes their use suitable in different fields, such as life science, electronics and chemical engineering ( Jeevanandam et al., 2018 ). Recently, nanotechnology is gaining interest also in plant science, due to the need to develop miniaturized efficient systems to improve seed germination, growth and plant protection to abiotic and biotic stresses ( Wang et al., 2016 ).
Metallic nanoparticles (NPs), such as gold (Au), and silver (Ag) NPs, have been widely introduced in plant science for different applications ( Figure 1A ). Their chemical synthesis is quite costly and requires the use of hazardous chemicals ( Viswanath and Kim, 2015 ; Rastogi et al., 2019 ). However, greener approaches based on the use of plant extract as well as ionizing radiation chemistry in aqueous solutions have been developed ( Abedini et al., 2013 ). Also oxidized NMs, such as MgO, CaO, ZnO, and TiO 2 NMs, have been widely proposed, thanks to their superior electrical, catalytic and light absorption properties ( Jahan et al., 2018 ). Over the recent years, the interest in polymeric nanomaterials is predominantly increasing due to their biocompatibility, low-cost synthesis and capability to response to external stimuli ( Baskar et al., 2018 ). Core/Shell NPs are also available and can be manufactured with a variety of combination of materials such as inorganic/inorganic, inorganic/organic, organic/inorganic, and organic/organic materials. The choice of the shell of the NPs strongly depends on the end application and use ( Ghosh Chaudhuri and Paria, 2012 ). For example, polymeric shells have been proposed to improve the biocompatibility of the NPs ( Nath et al., 2008 ). NPs with a nanostructured shell have been also synthesized, such as mesoporous silica nanoparticles (NPs) made from a mesoporous structure with a highly functionalizable surface area ( Torney et al., 2007 ).
Figure 1. (A) Illustration of NMs grouped into several categories: carbon-based NMs such as fullerenes and carbon nanotubes, including single-walled carbon nanotubes (SWCNTs) or multi-walled carbon nanotubes (MWCNTs); metallic NPs, including metals such as gold (Au), silver (Ag), aluminum (Al); metal oxides (ZnO, CuO, TiO 2 , Fe 2 O3, SiO 2 , etc.); quantum dots (QDs); dendrimers, which are three dimensional polymer network immensely branched with low polydispersity and liposomes and nanogels. With the development of new techniques for chemical synthesis, it is possible to synthesize NMs not only with a symmetrical (spherical) shape but also having a variety of different nanoforms, such as nanoclays (polypropylene nanoclay systems) and nanoemulsions (lipophilic nanoemulsions), tubes, rods, disks, bars, and sheets. (B) Schematization of different NP delivery methods and translocation in plants. Nanoparticle can be administered both at foliar and root system. Once penetrated the external layers, they move through the symplastic or apoplastic routes and reach different organs and tissues. (C) Currently, the main focus of the publications in plant science deals with the use of NPs as biosensors or biomolecules nanocarriers for crop production and protection under controlled conditions. New advances in DNA/miRNA/siRNA delivery have found limited application in plant so far, while new nanotechnology tools addressing technical concerns in genome editing strategies are strongly demanded.
Nanogels (NGs) are a new category of NM with a growing interest in the nanotechnology community. They have excellent physicochemical properties, colloidal stability, high encapsulation capacity of biomolecules (bioconjugation), and stimuli-responsiveness (pH, temperature, etc.). NGs are defined as nano-sized ionic and non-ionic hydrogels made of synthetic or natural polymeric chains, chemically or physically cross-linked ( Molina et al., 2015 ; Neamtu et al., 2017 ). NGs possess a high water content (70–90% of the entire structure), a high degree of porosity and high load capacity. The most common NGs are chitosan, alginate, poly(vinyl alcohol), poly(ethylene oxide), poly(ethyleneimine), poly (vinylpyrrolidone), poly(N-isopropylacrylamide). NGs with hybrid structures, made of polymeric or non-polymeric materials can be obtained ( Molina et al., 2015 ). Hybrid NGs have been classified in: (i) nanomaterial– nanogel, which are synthesized by incorporation of nanosized materials such as magnetic or carbonaceous nanoparticles, and (ii) polymer–nanogel composites, which include interpenetrated networks (IPNs), copolymer, and core-shell particles ( Molina et al., 2015 ). The main advantage of IPNs and copolymer NGs relies on their stimuli-responsiveness, whereas core-shell NGs are more promising for encapsulating biomolecules and drug delivery.
Nanoparticle Uptake, Translocation, and Biological Impact in Plants
Applications of nanotechnology strategies in plants need a preventive accurate evaluation of nanoparticle-plant interactions, including the comprehension of the mechanisms of their uptake, translocation and accumulation, together with the assessment of potential adverse effects on plant growth and development. Plant uptake of NPs is hardly predictable, depending on multiple factors related to the nanoparticle itself (size, chemical composition, net charge and surface functionalization), but also on the application routes, the interactions with environmental components (soil texture, water availability, microbiota), the constraint due to the presence of a cell wall, the physiology and the multifaceted anatomy of individual plant species. Most of the previous studies in plants deal with the uptake of small metal and metal oxide NPs, due to the wide use in industry and to the easy detection and tracking by microscopy techniques ( González-Melendi et al., 2008 ). However, compared to the great wealth of information available in metazoans, only a handful of integrated comparative analyses have been conceived to establish the contribution of the physicochemical features (e.g., size, charge, coatings, etc.) of NPs in plant-nanoparticle interaction ( Zhu et al., 2012 ; Song et al., 2013 ; Moon et al., 2016 ; Vidyalakshmi et al., 2017 ; García-Gómez et al., 2018 ).
Delivery Methods and Primary Interactions at the Plant Surface
Basically, engineered nanomaterials can be applied either to the roots or to the vegetative part of plants, preferentially to the leaves ( Figure 1B ). At the shooting surface, NPs can be taken up passively through natural plant openings with nano- or microscale exclusion size, such as stomata, hydathodes, stigma and bark texture ( Eichert et al., 2008 ; Kurepa et al., 2010 ). However, additional plant anatomical and physiological aspects need to be considered to better understand the dynamics of NP-plant interactions. For instance, shoot surfaces are generally covered by a cuticle made of biopolymers (e.g., cutin, cutan) and associated waxes, which function as a lipophilic barrier to protect above-ground plant primary organs, leaving access only through natural openings ( Figure 1B ). Dynamics of NPs at the cuticle level are poorly investigated, but at present, this barrier appears to be an almost impenetrable layer to nanoparticles, although nano-TiO2 has been shown to be able to produce holes in the cuticle ( Larue et al., 2014 ; Schwab et al., 2016 ). Trichomes on plant organs can affect dynamics at the plant surface by entrapping NP on the plant surface and thus increasing the permanence time of exogenous materials on tissues. Damages and wounds may also function as viable routes for NP internalization in plants in both aerial and hypogeal parts ( Al-Salim et al., 2011 ). Delivery methods also seem to influence NP uptake efficiency in plants. As recently reported, the aerosol application promotes higher internalization rates of different nanoparticles with respect to NP drop cast in watermelon ( Raliya et al., 2016 ). Also, leaf lamina infiltration strategies may force NM penetration in plant tissues as reported for single-walled carbon nanotubes ( Giraldo et al., 2014 ) and resulted to be functional for gene delivery ( Demirer et al., 2018 ). At the root level, rhizodermis lateral root junctions may provide easy access to NMs, especially near the root tip, while upper parts are impermeable due to the presence of suberin ( Chichiriccò and Poma, 2015 ). Generally, the dynamics of NP uptake appear to be more complex in the soil compared to the plant aerial part. Several factors, as the presence of mucilage and exudates, symbiotic organisms, and soil organic matter may influence NPs availability. For instance, root mucilage and exudates normally excreted into the rhizosphere play a dual role: they may promote NP adhesion to the root surface, which in turn may enhance NP internalization rate or, conversely, these gel-like substances may also trigger NP trapping and aggregation ( Avellan et al., 2017 ; Milewska-Hendel et al., 2017 ). Recent observations, by means of X-ray computed nanotomography and enhanced dark-field microscopy combined with hyperspectral imaging, have demonstrated that root border cells and associated mucilage tend to trap gold NPs irrespective of particle charge, while negatively charged NPs are not sequestered by the mucilage of Arabidopsis thaliana root cap and translocate directly into the root tissue ( Avellan et al., 2017 ).
The presence of symbiotic bacteria and fungi in the soil have been demonstrated to play controversial roles as well; in general, they enhance accumulation of different types of heavy metal NPs in true grasses, but reduce nano-Ag and nano-FeO uptake in legumes ( Whiteside et al., 2009 ; Feng et al., 2013 ; Guo and Chi, 2014 ).
Nanoparticle Mobilization in Plant
Once penetrated the plant outer protective layers and regardless of aerial or hypogeal exposure, NMs have two mobilization routes in the plant: apoplastic and symplastic paths ( Figure 1B ). Apoplastic transport occurs outside the plasma membrane through the cell wall and extracellular spaces, whereas symplastic movements involve the transport of water and solutes between the cytoplasm of adjacent cells connected by plasmodesmata and sieve plate pores.
Apoplastic transport has been demonstrated to promote radial movement of NMs, which may move NPs to the root central cylinder and the vascular tissues, and promoting their movement upwards the aerial part ( González-Melendi et al., 2008 ; Larue et al., 2014 ; Sun et al., 2014 ; Zhao et al., 2017 ). This manner of NP translocation is instrumental for applications requiring systemic NP delivery. However, the Casparian strip, a longitudinally oriented layer made of lignin-like structures, prevent the completion of this radial movement in the root endodermis ( Sun et al., 2014 ; Lv et al., 2015 ). To bypass this natural barrier, water and another solute switch from apoplastic to the simplastic path. Similar abilities to circumvent the block at Casparian strip have been documented for different kinds of NPs as reviewed in Schwab et al. (2016) . This may happen especially in those anatomical regions where the Casparian strip is not yet properly formed, such as root tips and root lateral junctions ( Lv et al., 2019 ).
The symplastic transport of NPs requires that at some point NPs penetrate inside the cells. The presence of a rigid plant cell wall creates a physical barrier to the cell entry and makes the intracellular delivery of NPs in plants much more difficult with respect to animal cells. Basically, the cell wall is a multi-layered framework of primarily cellulose/hemicellulose microfibrils and scaffold proteins, creating a porous milieu which acts as a narrow selective filter with a mean diameter <10 nm, with some exception up to 20 nm ( Carpita et al., 1979 ). Actually, this is a critical point and currently represents one of the main hurdles to the design and the implementation of bioengineering tools in plants ( Cunningham et al., 2018 ). However, different types of nanoparticles with a mean diameter between 3 and 50 nm and carbon nanotubes have been demonstrated to easily pass through the cell wall in many plant species ( Liu et al., 2009 ; Kurepa et al., 2010 ; Chang et al., 2013 ; Etxeberria et al., 2019 ).
Subsequent cell internalization may occur preferentially by endocytosis ( Valletta et al., 2014 ; Palocci et al., 2017 ), although alternative cell entry mechanisms, such as those based on pore formation, membrane translocation or carrier proteins already described in cells ( Nel et al., 2009 ; Lin et al., 2010 ; Wang et al., 2012 ) and in invertebrate models ( Marchesano et al., 2013 ) need to be further elucidated in plant cells. For instance, it has been demonstrated that Multi-Walled Carbon nanotubes (MWCNTs) may enter in Catharanthus roseus protoplasts by an endosome-escaping uptake mode ( Serag et al., 2011 ).
Once in the cytoplasm, cell to cell movements of NPs are facilitated by plasmodesmata, membrane-lined cytoplasmic bridges with a flexible diameter (20–50 nm), which ensure membrane and cytoplasmic continuity among cells throughout plant tissues. Transport of NPs with variable sizes through plasmodesmata has been described in Arabidopsis, rice, and poplar plant species ( Lin et al., 2009 ; Geisler-Lee et al., 2013 ; Zhai et al., 2014 ).
Through the symplastic and apoplastic pathways, small particles can reach the xylem and phloem vessels and translocate in the whole plant to different tissues and organs. Remarkably, organs like flowers, fruits and seeds normally have a strong capability to import fluids from the phloem (sink activity) and tend to accumulate NMs. Besides plant toxicity, NP accumulation in specialized organs raises another important issue related to their safe use in human and animal consumption ( Pérez-de-Luque, 2017 ).
Worth mentioning from an application perspective, studies in different crops, such as maize, spinach, cabbage, reported the ability of metal-NPs to penetrate seeds and translocate into the seedlings, without significant effects on seed viability, germination rate, and shoot development. These data suggest the possible use of functional NPs for seed priming and plant growth stimulation, also in limiting environmental conditions ( Zheng et al., 2005 ; Rǎcuciu and Creangǎ, 2009 ; Pokhrel and Dubey, 2013 ).
Nanoparticle Phytotoxicity
The comprehension of NM toxicity in crop plants is still at dawn, but it is crucial for the implementation of innovative agro-nanotech tools and products ( Servin and White, 2016 ). Current NP studies in plants have investigated unrealistic scenarios, such as short-term and high dose exposure, often in model media and plant species, gathering contradictory results ( Miralles et al., 2012 ). Basically, most of the studies have demonstrated that in cultivated species (e.g., tomato, wheat, onion, and zucchini) excess of metal-based NPs trigger an oxidative burst by interfering with the electron transport chain as well as by impairing the reactive oxygen species (ROS) detoxifying machinery, with genotoxic implications ( Dimkpa et al., 2013 ; Faisal et al., 2013 ; Pakrashi et al., 2014 ; Pagano et al., 2016 ). As a consequence, plant secondary metabolism, hormonal balance and growth are often negatively affected. Interestingly, recent transcriptome analyses revealed that exposures to different types of NPs (e.g., zinc oxide, fullerene soot, or titanium dioxide) exposure represses a significant number of genes involved in phosphate-starvation, pathogen and stress responses, with possible negative effects on plant root development and defense mechanisms in A. thaliana . A recent systems biology approach, including omics data from tobacco, rice, rocket salad, wheat, and kidney beans, confirmed that metal NMs provoke a generalized stress response, with the prevalence of oxidative stress components ( Ruotolo et al., 2018 ). These data suggest that further studies based on high-throughput analysis of genetic and metabolic responses, triggered by NP exposure, are necessary to shed light on many aspects of NP phytotoxicity in crops, even in absence of overt toxicity at the phenotypic level ( Majumdar et al., 2015 ). In light of these evidence, it appears fair to exploit for future applications in plants engineered NMs for which a safe profile has been already established in animal systems, such as soft polymeric NPs.
Current Applications in Plant Science
As mentioned above, while nanotechnology innovation is running fast in many fields of life science, smart applications in plant and agricultural science still lag behind ( Wang et al., 2016 ). In this section, we review the most significant current approaches (schematized in Figure 1C ), in particular, those inherent to biosensing, delivery of agrochemicals and genetic engineering. Representative applications for different types of NPs are also listed in Table 1 together with a brief description of their positive effects and drawbacks in plant species.
Table 1 . Major applications of different nanomaterials in plant and respective positive/negative impact.
NMs have been applied to develop biosensors or they have been used as “sensing materials” in the fields of crop biotechnology, agriculture, and food industry ( Duhan et al., 2017 ; Chaudhry et al., 2018 ). Different categories of nanosensor types have been tested in plants, including plasmonic nanosensors, fluorescence resonance energy transfer (FRET)-based nanosensors, carbon-based electrochemical nanosensors, nanowire nanosensors and antibody nanosensors. Although the use of nanosensors in plants is at an initial stage ( Rai et al., 2012 ), interesting reports have proposed the use of NMs as tools for detection and quantification of plant metabolic flux, residual of pesticides in food and bacteria, viral and fungal pathogens. Recently, it has been reported the fabrication of a fluorometric optical onion membrane-based sensor for detection of sucrose based on the synthesis of invertase-nanogold clusters embedded in plant membranes ( Bagal-Kestwal et al., 2015 ). In addition, single-walled carbon nanotubes (SWNTs) have been exploited for near-infrared fluorescence monitoring of nitric oxide in A. thaliana ( Giraldo et al., 2014 ). FRET probes conjugated to polystyrene NPs have been also designed to quantify and recognize the phytoalexins ( Dumbrepatil et al., 2010 ).
As above mentioned, NMs-based biosensors are very promising as they allow rapid detection and precise quantification of fungi, bacteria and viruses in plants ( Duhan et al., 2017 ). For example, fluorescent silica NPs combined with antibody was designed for diagnosing Xanthomonas axonopodis pv. vesicatoria , which causes bacterial spot disease in Solanaceae plants ( Yao et al., 2009 ). Recently, Au NPs have been proposed from Lau et al. as DNA biochemical labels to detect Pseudomonas syringae in A. thaliana by differential pulse voltammetry (DPV) on disposable screen-printed carbon electrodes ( Lau et al., 2017 ). Similarly, fluorescently labeled-DNA oligonucleotide conjugated to Au NPs were employed in the diagnosis of the phytoplasma associated with the flavescence dorée disease of grapevine ( Firrao et al., 2005 ). Finally, smart nanosensors are also available for mycotoxin detection; for instance, the 4mycosensor is a competitive antibody-based assay successfully introduced in the market to test the presence of ZEA, T-2/HT-2, DON, and FB1/FB2 mycotoxin residues in corn, wheat, oat and barley ( Lattanzio and Nivarlet, 2017 ).
Controlled Release of Agrochemicals and Nutrients
NMs can be applied to the soil as nanostructured fertilizers (nanofertilizers, as for Fe, Mn, Zn, Cu, Mo NPs) or can be used as enhanced delivery systems to improve the uptake and the performance of conventional fertilizers (nutrients and phosphates) ( Liu and Lal, 2015 ). Even though nanofertilizers and NM-enhanced fertilizers are very promising for agriculture, the use of nanotechnology in fertilizer supply is very scanty ( DeRosa et al., 2010 ).
Hydroxyapatite nanoparticles, used as phosphorous nanofertilizers, enhance the soybean growth rate and seed yield by 33 and 20%, compared to a regular P fertilizer ( Liu and Lal, 2015 ). In addition, nanofertilizers can be released at slower rates which may contribute to maintain the soil fertility by reducing the transport of these nutrients into a runoff or ground water and decreasing the risks of environmental pollution and toxic effects due to their over-application ( Liu and Lal, 2015 ).
Metallic nanoparticles based on Iron oxide, ZnO, TiO 2 , and copper have been directly applied as nanofertilizers in soil by irrigation or via foliar applications in different plants, such as mung bean plant, cucumber and rape ( Gao et al., 2006 ; Tarafdar et al., 2014 ; Saharan et al., 2016 ; Verma et al., 2018 ). Similarly, MWNTs used as soil supplements increased twice the number of flowers and fruits in tomato plants likely through the activation of genes/proteins essential for plant growth and development ( Khodakovskaya et al., 2013 ). Despite these intriguing evidence, the use of nanofertilizers is still debatable. Accumulation in treated soils may pose a threat to soil microbial communities such as small invertebrates, bacteria and fungi ( Frenk et al., 2013 ; Waalewijn-Kool et al., 2013 ; Shen et al., 2015 ; Simonin et al., 2016 ; Goncalves et al., 2017 ). This impact on the agro-ecosystem reasonably discourages the use of metallic nanoparticles in agriculture.
Only recently, a natural polymer, such as chitosan NPs, have been used for controlled release of nitrogen, phosphorus and potassium in wheat by foliar uptake ( Abdel-Aziz et al., 2016 ). The use of organic NPs is more acceptable in terms of environmental pollution. However, their effective advantages for nutrient supply over traditional fertilization methods need more robust evidence ( Liu and Lal, 2015 ).
On the other hand, pesticides delivered by nanomaterials generally have increased stability and solubility and enable slow release and effective targeted delivery in pest management ( Duhan et al., 2017 ). Organic and polymeric NPs in the form of nanospheres or nanocapsules have been used as nanocarriers for herbicide distribution ( Tanaka et al., 2012 ). In particular, polymeric NPs, such as Poly(epsilon-caprolactone), present good properties of biocompatibility and have been repeatedly used for the encapsulation of atrazine herbicide ( Tanaka et al., 2012 ). In another study, chitosan nanoparticles loaded with three triazine herbicides have shown reduced environmental impact and low genotoxic effects in Allium cepa ( Grillo et al., 2015 ).
Nanomaterials for Plant Genetic Engineering
As stated above, the cell wall represents a barrier to the delivery of exogenous biomolecules in plant cells. To overcome this barrier and achieve plant genetic transformation, different strategies based on Agrobacterium transformation or biolistic methods are worldwide used for DNA delivery in plant cells. Limitations to these approaches rely on narrow host range and plant extensive damages, which often inhibit plant development.
Most of the pioneering studies for nanomaterial-based plant genetic engineering have been conducted in plant cell cultures. For example, Silicon Carbide-Mediated Transformation has been reported as a successful approach to deliver DNA in different calli (tobacco, maize, rice, soybean and cotton) ( Armstrong and Green, 1985 ; Wang et al., 1995 ; Serik et al., 1996 ; Asad and Arsh, 2012 ; Lau et al., 2017 ).
Although lagged behind the advancements achieved in animal systems, results reported recently in plants are proving that NMs may overcome the barrier of the cell wall in adult plants and reduce the drawbacks associated with current transgene delivery systems.
One seminal study proved that dsRNA of different plant viruses can be loaded on non-toxic, degradable, layered double hydroxide (LDH) clay nanosheets or BioClay. The dsRNAs and/or their RNA breakdown products provide protection against the Cauliflower Mosaic Virus (CMV) in sprayed tobacco leaves, but they also confer systemic protection to newly emerged, unsprayed leaves on viral challenge 20 days after a single spray treatment in tobacco ( Mitter et al., 2017 ). More in general, this is a proof of concept for species-independent and passive delivery of genetic material, without transgene integration, into plant cells for different biotechnology applications in plants.
A successful stable genetic transformation has been achieved in cotton plants via magnetic nanoparticles (MNPs). β-glucuronidase (GUS) reporter gene- MNP complex were infiltrated into cotton pollen grains by magnetic force, without compromising pollen viability. Through pollination with magnetofected pollen, cotton transgenic plants were successfully generated and exogenous DNA was successfully integrated into the genome, effectively expressed, and stably inherited in the offspring obtained by selfing ( Zhao et al., 2017 ).
In another recent paper, carbon nanotubes scaffolds applied to external plant tissue by infusion were used to deliver linear and plasmid DNA, as well as siRNA, in Nicotiana benthamiana, Eruca sativa, Triticum aestivum , and Gossypium hirsutum leaves and in E. sativa protoplasts, resulting in a strong transient Green Fluorescent Protein (GFP) expression. Moreover, the same authors reported that small interfering RNA (siRNA) was delivered to N . benthamiana plants constitutively expressing GFP, causing a 95% silencing of this gene ( Demirer et al., 2018 ).
The first and promising approach of genome editing mediated by mesoporous silica nanoparticles (MSNs) has been recently proposed. MSNs have used as carriers to deliver Cre recombinase in Zea mays immature embryos, carrying loxP sites integrated into chromosomal DNA. After the biolistic introduction of engineered MSNs in plant tissues, the loxP was correctly recombined establishing a successful genome editing ( Valenstein et al., 2013 ).
Conclusions and Future Perspectives
Herein, we have discussed various facets of using NMs in plant sciences. In the last years, it has been demonstrated that nanotechnology has made huge progress in the synthesis of NMs and their application in medicine for diagnosis and therapy. On the other side, the application of NMs for plants is still poor. Recent outcomes and current applications suggest that more studies are necessary for this direction to optimize the synthesis and biofunctionalization of NMs for plant applications, but also to elucidate deeper the mechanisms of plant uptake and improving the sustainability for agro-ecosystems and human health. Interestingly, applications need to be extended to address uncovered important aspects of plant physiology. For instance, nanobiosensors for detecting secondary metabolites or phytoregulators in real time may provide advances in monitoring plant development and interactions with the environment, especially in limiting growth conditions.
Despite the huge progress in plant genetics, the delivery of exogenous DNA and/or enzymes for genome editing remain a big challenge. New strategies based on nanoparticle-mediated clustered regularly interspersed palindromic repeats—CRISPR associated proteins (CRISPR-Cas9) technology, as those tested in other biological systems ( Lee et al., 2017 ; Glass et al., 2018 ), would provide ground-breaking innovation in plant genetics.
On the base of consolidated evidence reported in cell and animal models, soft materials, like nanogels, and polymeric nanostructures should be further exploited as favorable candidates to develop new strategies for controlled release of biomolecules and plant genome editing. Owing to their safe profile, high loading capacity and excellent cargo protection from degradation polymeric and hydrogel-based NPs have shown undeniable advantages in drug delivery. Moreover, this kind of NMs has been elegantly employed to achieve a controlled (spatial and temporal) release of cargos triggered by external stimuli (e.g., UV, NIR, acoustic waves etc.) ( Ma et al., 2013 ; Ambrosone et al., 2016 ; Linsley and Wu, 2017 ) in cell and animal models. These outstanding results suggest that the huge potential of soft nanomaterials remains almost unexplored in plants. Besides a few successful attempts for agrochemicals delivery above-mentioned and listed in Table 1 , more efforts are needed to design strategies and smart tools based on polymeric or hybrid materials for applications in plants. Of course, a careful analysis of manufacturing scalability and cost-effectiveness needs to be undertaken before the extensive use of polymeric nanomaterials in agriculture.
As a final remark, the delay in plant nanotechnology might be overcome by encouraging the activation of multidisciplinary approaches for the design and the synthesis of smart nanomaterials. To this aim, joint collaborative initiatives, merging complementary professional competencies such those of plant biologists, geneticists, chemists, biochemists, and engineers, may disclose new horizons in phytonanotechnology.
Author Contributions
IS and AA conceived the idea and organized this mini review. All authors wrote the manuscript and approved the contents for publication.
Conflict of Interest Statement
The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest.
Abdel-Aziz, H. M. M., Hasaneen, M. N. A., and Omer, A. M. (2016). Nano chitosan-NPK fertilizer enhances the growth and productivity of wheat plants grown in sandy soil. Spanish J. Agric. Res. 14, 1–9. doi: 10.5424/sjar/2016141-8205
CrossRef Full Text | Google Scholar
Abedini, A., Daud, A. R., Hamid, M. A. A., Othman, N. K., and Saion, E. (2013). A review on radiation-induced nucleation and growth of colloidal metallic nanoparticles. Nanoscale Res. Lett. 8, 1–10. doi: 10.1186/1556-276X-8-474
PubMed Abstract | CrossRef Full Text | Google Scholar
Alawadhi, H., Ramamoorthy, K., Mosa, K. A., Elnaggar, A., Ibrahim, E., El-Naggar, M., et al. (2018). Copper nanoparticles induced genotoxicty, oxidative stress, and changes in Superoxide Dismutase (SOD) gene expression in cucumber ( Cucumis sativus ) plants. Front. Plant Sci. 9:872. doi: 10.3389/fpls.2018.00872
Almutairi, Z. M., and Alharbi, A. (2015). Effect of silver nanoparticles on seed germination of crop plants. Int. J. Biol. Biomol. Agric. Food Biotechnol. Eng. 9, 572–576. doi: 10.24297/jaa.v4i1.4295
Al-Salim, N., Barraclough, E., Burgess, E., Clothier, B., Deurer, M., Green, S., et al. (2011). Quantum dot transport in soil, plants, and insects. Sci. Total Environ. 409:3237–3248.doi: 10.1016/j.scitotenv.2011.05.017
Ambrosone, A., Marchesano, V., Carregal-Romero, S., Intartaglia, D., Parak, W. J., and Tortiglione, C. (2016). Control of Wnt/β-catenin signaling pathway in vivo via light responsive capsules. ACS Nano 10, 4828–4834. doi: 10.1021/acsnano.5b07817
Armstrong, C. L., and Green, C. E. (1985). Establishment and maintenance of friable, embryogenic maize callus and the involvement of L-proline. Planta 164:207–214. doi: 10.1007/BF00396083
Asad, S., and Arsh, M. (2012). “Silicon carbide whisker-mediated plant transformation,” in Properties and Applications of Silicon Carbide , ed R. Gerhardt (Rijeka: BoD-Books on Deman), 1–16. doi: 10.5772/15721
Astm E2456 - 06 (2012). (2006)Standard Terminol. Relat. to Nanotechnol. 06, 5–6. doi: 10.1520/E2456-06R12
Avellan, A., Schwab, F., Masion, A., Chaurand, P., Borschneck, D., Vidal, V., et al. (2017). Nanoparticle uptake in plants: gold nanomaterial localized in roots of Arabidopsis thaliana by X-ray computed nanotomography and hyperspectral imaging. Environ. Sci. Technol. 51, 8682–8691. doi: 10.1021/acs.est.7b01133
Bagal-Kestwal, D., Kestwal, R. M., and Chiang, B. H. (2015). Invertase-nanogold clusters decorated plant membranes for fluorescence-based sucrose sensor. J. Nanobiotechnology 13:30. doi: 10.1186/s12951-015-0089-1
Baskar, V., Meeran, S., Shabeer, S. T. K, and Subramani Sruthi, Ali, J. (2018). Historic review on modern herbal nanogel formulation and delivery methods. Int. J. Pharm. Pharm. Sci. 10, 1–10. doi: 10.22159/ijpps.2018v10i10.23071
Bruchez, M., Moronne, M., Gin, P., Weiss, S., and Alivisatos, A. P. (1998). Semiconductor nanocrystals as fluorescent biological labels. Science 281, 2013–2016. doi: 10.1126/science.281.5385.2013
Carpita, N., Sabularse, D., Montezinos, D., and Delmer, D. P. (1979). Determination of the pore size of cell walls of living plant cells. Science 205, 1144–1147. doi: 10.1126/science.205.4411.1144
Chang, F. P., Kuang, L. Y., Huang, C. A., Jane, W. N., Hung, Y., Hsing, Y. I. C., et al. (2013). A simple plant gene delivery system using mesoporous silica nanoparticles as carriers. J. Mater. Chem. B 1, 5279–5287. doi: 10.1039/c3tb20529k
Chaudhry, N., Dwivedi, S., Chaudhry, V., Singh, A., Saquib, Q., Azam, A., et al. (2018). Bio-inspired nanomaterials in agriculture and food: current status, foreseen applications and challenges. Microb. Pathog. 123, 196–200. doi: 10.1016/j.micpath.2018.07.013
Chichiriccò, G., and Poma, A. (2015). Penetration and toxicity of nanomaterials in higher plants. Nanomaterials 5, 851–873. doi: 10.3390/nano5020851
Cunningham, F. J., Goh, N. S., Demirer, G. S., Matos, J. L., and Landry, M. P. (2018). Nanoparticle-mediated delivery towards advancing plant genetic engineering. Trends Biotechnol. 36, 882–897. doi: 10.1016/j.tibtech.2018.03.009
Dan, Y., Zhang, W., Xue, R., Ma, X., Stephan, C., and Shi, H. (2015). Characterization of gold nanoparticle uptake by tomato plants using enzymatic extraction followed by single-particle inductively coupled plasma-mass spectrometry analysis. Environ. Sci. Technol. 49, 3007–3014. doi: 10.1021/es506179e
Dasgupta, A., Chakraborty, N., Panda, K., Chandra, S., Acharya, K., and Sarkar, J. (2015). Chitosan nanoparticles: a positive modulator of innate immune responses in plants. Sci. Rep. 5:15195. doi: 10.1038/srep15195
De La Torre-Roche, R., Hawthorne, J., Deng, Y., Xing, B., Cai, W., Newman, L. A., et al. (2013). Multiwalled carbon nanotubes and C60 fullerenes differentially impact the accumulation of weathered pesticides in four agricultural plants. Environ. Sci. Technol. 47, 12539–12547. doi: 10.1021/es4034809
Demirer, G. S., Zhang, H., Matos, J., Goh, N., Cunningham, F. J., Sung, Y., et al. (2018). High aspect ratio nanomaterials enable delivery of functional genetic material without DNA integration in mature plants. bioRxiv 10, 1–32. doi: 10.1101/179549
DeRosa, M. C., Monreal, C., Schnitzer, M., Walsh, R., and Sultan, Y. (2010). Nanotechnology in fertilizers. Nat. Nanotechnol. 5, 91–91. doi: 10.1038/nnano.2010.2
Dimkpa, C. O., McLean, J. E., Martineau, N., Britt, D. W., Haverkamp, R., and Anderson, A. J. (2013). Silver nanoparticles disrupt wheat ( Triticum aestivum L.) growth in a sand matrix. Environ. Sci. Technol. 47, 1082–1090. doi: 10.1021/es302973y
Duhan, J. S., Kumar, R., Kumar, N., Kaur, P., Nehra, K., and Duhan, S. (2017). Nanotechnology: the new perspective in precision agriculture. Biotechnol. Rep. 15, 11–23. doi: 10.1016/j.btre.2017.03.002
Dumbrepatil, A. B., Lee, S. G., Chung, S. J., Lee, M. G., Park, B. C., Kim, T. J., et al. (2010). Development of a nanoparticle-based FRET sensor for ultrasensitive detection of phytoestrogen compounds. Analyst 135, 2879–2886. doi: 10.1039/c0an00385a
Eichert, T., Kurtz, A., Steiner, U., and Goldbach, H. E. (2008). Size exclusion limits and lateral heterogeneity of the stomatal foliar uptake pathway for aqueous solutes and water-suspended nanoparticles. Physiol. Plant. 134, 151–160. doi: 10.1111/j.1399-3054.2008.01135.x
Etxeberria, E., Gonzalez, P., Bhattacharya, P., Sharma, P., and Ke, P. C. (2019). Determining the size exclusion for nanoparticles in citrus leaves. Hort Sci. 51, 732–737. doi: 10.21273/HORTSCI.51.6.732
Faisal, M., Saquib, Q., Alatar, A. A., Al-Khedhairy, A. A., Hegazy, A. K., and Musarrat, J. (2013). Phytotoxic hazards of NiO-nanoparticles in tomato: a study on mechanism of cell death. J. Hazard. Mater. 250–251, 318–332. doi: 10.1016/j.jhazmat.2013.01.063
Fathi, A., Zahedi, M., Torabian, S., and Khoshgoftar, A. (2017). Response of wheat genotypes to foliar spray of ZnO and Fe2O3 nanoparticles under salt stress. J. Plant Nutr. 40, 1376–1385. doi: 10.1080/01904167.2016.1262418
Feng, Y., Cui, X., He, S., Dong, G., Chen, M., Wang, J., et al. (2013). The role of metal nanoparticles in influencing arbuscular mycorrhizal fungi effects on plant growth. Environ. Sci. Technol. 47, 9496–9504. doi: 10.1021/es402109n
Firrao, G., Moretti, M., Ruiz Rosquete, M., Gobbi, E., and Locci, R. (2005). Nanobiotransducer for detecting flavescence dorée phytoplasma. J. Plant Pathol. 87, 101–107. doi: 10.4454/jpp.v87i2.903
Frenk, S., Ben-Moshe, T., Dror, I., Berkowitz, B., and Minz, D. (2013). Effect of metal oxide nanoparticles on microbial community structure and function in two different soil types. PLoS ONE 8:e84441. doi: 10.1371/journal.pone.0084441
Gao, F., Hong, F., Liu, C., Zheng, L., Su, M., Wu, X., et al. (2006). Mechanism of nano-anatase TiO2 on promoting photosynthetic carbon reaction of spinach: inducing complex of Rubisco-Rubisco activase. Biol. Trace Elem. Res. 111, 239–253. doi: 10.1385/BTER:111:1:239
Gao, F., Liu, C., Qu, C., Zheng, L., Yang, F., Su, M., et al. (2008). Was improvement of spinach growth by nano-TiO2 treatment related to the changes of Rubisco activase? BioMetals 21, 211–217. doi: 10.1007/s10534-007-9110-y
García-Gómez, C., Obrador, A., González, D., Babín, M., and Fernández, M. D. (2018). Comparative study of the phytotoxicity of ZnO nanoparticles and Zn accumulation in nine crops grown in a calcareous soil and an acidic soil. Sci. Total Environ. 644, 770–780. doi: 10.1016/j.scitotenv.2018.06.356
Geisler-Lee, J., Wang, Q., Yao, Y., Zhang, W., Geisler, M., Li, K., et al. (2013). Phytotoxicity, accumulation and transport of silver nanoparticles by Arabidopsis thaliana . Nanotoxicology 7, 323–337. doi: 10.3109/17435390.2012.658094
Ghosh Chaudhuri, R., and Paria, S. (2012). Core/shell nanoparticles: classes, properties, synthesis mechanisms, characterization, and applications. Chem. Rev. 112, 2373–2433. doi: 10.1021/cr100449n
Giraldo, J. P., Landry, M. P., Faltermeier, S. M., McNicholas, T. P., Iverson, N. M., Boghossian, A. A., et al. (2014). Plant nanobionics approach to augment photosynthesis and biochemical sensing. Nat. Mater. 13, 400–408. doi: 10.1038/nmat3890
Glass, Z., Lee, M., Li, Y., and Xu, Q. (2018). Engineering the delivery system for CRISPR-based genome editing. Trends Biotechnol. 36, 173–185. doi: 10.1016/j.tibtech.2017.11.006
Goncalves, M. F. M., Gomes, S. I. L., Scott-Fordsmand, J. J., and Amorim, M. J. B. (2017). Shorter lifetime of a soil invertebrate species when exposed to copper oxide nanoparticles in a full lifespan exposure test. Sci. Rep. 7:1355. doi: 10.1038/s41598-017-01507-8
González-Melendi, P., Fernández-Pacheco, R., Coronado, M. J., Corredor, E., Testillano, P. S., Risueño, M. C., et al. (2008). Nanoparticles as smart treatment-delivery systems in plants: assessment of different techniques of microscopy for their visualization in plant tissues. Ann. Bot. 101, 187–195. doi: 10.1093/aob/mcm283
Gopinath, K., Gowri, S., Karthika, V., and Arumugam, A. (2014). Green synthesis of gold nanoparticles from fruit extract of Terminalia arjuna , for the enhanced seed germination activity of Gloriosa superba . J. Nanostructure Chem. 4:115. doi: 10.1007/s40097-014-0115-0
Grillo, R., Clemente, Z., Oliveira, J. L., de Campos, E. V. R., Chalupe, V. C., Jonsson, C. M., et al. (2015). Chitosan nanoparticles loaded the herbicide paraquat: the influence of the aquatic humic substances on the colloidal stability and toxicity. J. Hazard. Mater. 286, 562–572. doi: 10.1016/j.jhazmat.2014.12.021
Guo, J., and Chi, J. (2014). Effect of Cd-tolerant plant growth-promoting rhizobium on plant growth and Cd uptake by Lolium multiflorum Lam. and Glycine max (L.) Merr. in Cd-contaminated soil. Plant Soil 375, 205–214. doi: 10.1007/s11104-013-1952-1
Islam, P., Water, J. J., Bohr, A., and Rantanen, J. (2017). Chitosan-based nano-embedded microparticles: impact of Nanogel composition on physicochemical properties. Pharmaceutics 9, 1–12. doi: 10.3390/pharmaceutics9010001
Ivanov, I., Khodakovskaya, M., Dervishi, E., Lahiani, M. H., and Chen, J. (2016). Comparative study of plant responses to carbon-based nanomaterials with different morphologies. Nanotechnology 27:265102. doi: 10.1088/0957-4484/27/26/265102
Jahan, S., Alias, Y. B., Bakar, A. F. B. A., and Yusoff, I. B. (2018). Toxicity evaluation of ZnO and TiO2 nanomaterials in hydroponic red bean ( Vigna angularis ) plant: physiology, biochemistry and kinetic transport. J. Environ. Sci. 72, 140–152. doi: 10.1016/j.jes.2017.12.022
Jeevanandam, J., Barhoum, A., Chan, Y. S., Dufresne, A., and Danquah, M. K. (2018). Review on nanoparticles and nanostructured materials: history, sources, toxicity and regulations. Beilstein J. Nanotechnol. 9, 1050–1074. doi: 10.3762/bjnano.9.98
Karny, A., Zinger, A., Kajal, A., Shainsky-Roitman, J., and Schroeder, A. (2018). Therapeutic nanoparticles penetrate leaves and deliver nutrients to agricultural crops. Sci. Rep. 8:7589. doi: 10.1038/s41598-018-25197-y
Khan, M. N., Mobin, M., Abbas, Z. K., AlMutairi, K. A., and Siddiqui, Z. H. (2017). Role of nanomaterials in plants under challenging environments. Plant Physiol. Biochem. 110, 194–209. doi: 10.1016/j.plaphy.2016.05.038
Khodakovskaya, M. V., Kim, B. S., Kim, J. N., Alimohammadi, M., Dervishi, E., Mustafa, T., et al. (2013). Carbon nanotubes as plant growth regulators: effects on tomato growth, reproductive system, and soil microbial community. Small 9, 115–123. doi: 10.1002/smll.201201225
Kole, C., Kole, P., Randunu, K. M., Choudhary, P., Podila, R., Ke, P. C., et al. (2013). Nanobiotechnology can boost crop production and quality: first evidence from increased plant biomass, fruit yield and phytomedicine content in bitter melon ( Momordica charantia ). BMC Biotechnol. 13:37. doi: 10.1186/1472-6750-13-37
Koo, Y., Wang, J., Zhang, Q., Zhu, H., Chehab, E. W., Colvin, V. L., et al. (2015). Fluorescence reports intact quantum dot uptake into roots and translocation to leaves of arabidopsis thaliana and subsequent ingestion by insect herbivores. Environ. Sci. Technol. 49, 626–632. doi: 10.1021/es5050562
Kretzmann, J. A., Ho, D., Evans, C. W., Plani-Lam, J. H. C., Garcia-Bloj, B., Mohamed, A. E., et al. (2017). Synthetically controlling dendrimer flexibility improves delivery of large plasmid DNA. Chem. Sci. 8, 2923–2930. doi: 10.1039/C7SC00097A
Kurepa, J., Paunesku, T., Vogt, S., Arora, H., Rabatic, B. M., Lu, J., et al. (2010). Uptake and distribution of ultrasmall anatase TiO2 alizarin red s nanoconjugates in arabidopsis thaliana. Nano Lett. 10, 2296–2302. doi: 10.1021/nl903518f
Larue, C., Castillo-Michel, H., Sobanska, S., Cécillon, L., Bureau, S., Barthès, V., et al. (2014). Foliar exposure of the crop Lactuca sativa to silver nanoparticles: evidence for internalization and changes in Ag speciation. J. Hazard. Mater. 264, 98–106. doi: 10.1016/j.jhazmat.2013.10.053
Lattanzio, V. M. T., and Nivarlet, N. (2017). Multiplex dipstick immunoassay for semiquantitative determination of fusarium mycotoxins in oat in Methods Mol Biol. 1536, 137–142. doi: 10.1007/978-1-4939-6682-0_10
Lau, H. Y., Wu, H., Wee, E. J. H., Trau, M., Wang, Y., and Botella, J. R. (2017). Specific and sensitive isothermal electrochemical biosensor for plant pathogen DNA detection with colloidal gold nanoparticles as probes. Sci. Rep. 7:38896. doi: 10.1038/srep38896
Laware, S. L., and Raskar, S. (2014). Influence of zinc oxide nanoparticles on growth, flowering and seed productivity in onion. Int. J. Curr. Microbiol. App. Sci. 3, 874–881.
Google Scholar
Lee, K., Conboy, M., Park, H. M., Jiang, F., Kim, H. J., Dewitt, M. A., et al. (2017). Nanoparticle delivery of Cas9 ribonucleoprotein and donor DNA in vivo induces homology-directed DNA repair. Nat. Biomed. Eng. 1, 889–901. doi: 10.1038/s41551-017-0137-2
Lee, W. M., An, Y.-J., Yoon, H., and Kweon, H.-S. (2008). Toxicity and bioavailability of copper nanoparticles to the terrestrial plants mung bean ( Phaseolus radiatus ) and wheat. Environ. Toxicol. Chem. 27, 1915–1921. doi: 10.1897/07-481.1
Lin, D., and Xing, B. (2007). Phytotoxicity of nanoparticles: Inhibition of seed germination and root growth. Environ. Pollut. 150, 243–250. doi: 10.1016/j.envpol.2007.01.016
Lin, J., Zhang, H., Chen, Z., and Zheng, Y. (2010). Penetration of lipid membranes by gold nanoparticles: insights into cellular uptake, cytotoxicity, and their relationship. ACS Nano 4, 5421–5429. doi: 10.1021/nn1010792
Lin, S., Reppert, J., Hu, Q., Hudson, J. S., Reid, M. L., Ratnikova, T. A., et al. (2009). Uptake, translocation, and transmission of carbon nanomaterials in rice plants. Small 5, 1128–1132. doi: 10.1002/smll.200801556
Linsley, C. S., and Wu, B. M. (2017). Recent advances in light-responsive on-demand drug-delivery systems. Ther. Deliv. 8, 89–107. doi: 10.4155/tde-2016-0060
Liu, J., Williams, P. C., Goodson, B. M., Geisler-Lee, J., Fakharifar, M., and Gemeinhardt, M. E. (2019). TiO2nanoparticles in irrigation water mitigate impacts of aged Agnanoparticles on soil microorganisms, Arabidopsis thalianaplants , and Eisenia fetida earthworms. Environ. Res. 172, 202–215. doi: 10.1016/j.envres.2019.02.010
Liu, Q., Chen, B., Wang, Q., Shi, X., Xiao, Z., Lin, J., et al. (2009). Carbon nanotubes as molecular transporters for walled plant cells. Nano Lett. 9, 1007–1010. doi: 10.1021/nl803083u
Liu, R., and Lal, R. (2015). Potentials of engineered nanoparticles as fertilizers for increasing agronomic productions. Sci. Total Environ. 514, 131–139. doi: 10.1016/j.scitotenv.2015.01.104
Lv, J., Christie, P., and Zhang, S. (2019). Uptake, translocation, and transformation of metal-based nanoparticles in plants: recent advances and methodological challenges. Environ. Sci. Nano 6, 41–59. doi: 10.1039/C8EN00645H
Lv, J., Zhang, S., Luo, L., Zhang, J., Yang, K., and Christied, P. (2015). Accumulation, speciation and uptake pathway of ZnO nanoparticles in maize. Environ. Sci. Nano 2, 68–77. doi: 10.1039/C.4E.N.00064A
Ma, J., Du, L. F., Chen, M., Wang, H. H., Xing, L. X., Jing, L. F., et al. (2013). Drug-loaded nano-microcapsules delivery system mediated by ultrasound-targeted microbubble destruction: a promising therapy method. Biomed. Rep. 1, 506–510. doi: 10.3892/br.2013.110
Ma, X., and Wang, C. (2010). Fullerene nanoparticles affect the fate and uptake of trichloroethylene in phytoremediation systems. Environ. Eng. Sci. 27, 989–992. doi: 10.1089/ees.2010.0141
Majumdar, S., Almeida, I. C., Arigi, E. A., Choi, H., VerBerkmoes, N. C., Trujillo-Reyes, J., et al. (2015). Environmental effects of nanoceria on seed production of common bean ( Phaseolus vulgaris ): a proteomic analysis. Environ. Sci. Technol. 49, 13283–13293. doi: 10.1021/acs.est.5b03452
Malerba, M., and Cerana, R. (2018). Recent advances of chitosan applications in plants. Polymers. 10, 1–10. doi: 10.3390/polym10020118
Marchesano, V., Hernandez, Y., Salvenmoser, W., Ambrosone, A., Tino, A., Hobmayer, B., et al. (2013). Imaging inward and outward trafficking of gold nanoparticles in whole animals. ACS Nano 7, 2431–2442. doi: 10.1021/nn305747e
Milewska-Hendel, A., Zubko, M., Karcz, J., Stróz, D., and Kurczynska, E. (2017). Fate of neutral-charged gold nanoparticles in the roots of the Hordeum vulgare L. cultivar Karat. Sci. Rep. 7:3014. doi: 10.1038/s41598-017-02965-w
Miralles, P., Church, T. L., and Harris, A. T. (2012). Toxicity, uptake, and translocation of engineered nanomaterials in vascular plants. Environ. Sci. Technol. 46, 9224–9239. doi: 10.1021/es202995d
Mitter, N., Worrall, E. A., Robinson, K. E., Li, P., Jain, R. G., Taochy, C., et al. (2017). Clay nanosheets for topical delivery of RNAi for sustained protection against plant viruses. Nat. Plants 3:16207. doi: 10.1038/nplants.2016.207
Modlitbová, P., Porízka, P., Novotný, K., Drbohlavová, J., Chamradová, I., Farka, Z., et al. (2018). Short-term assessment of cadmium toxicity and uptake from different types of Cd-based quantum dots in the model plant Allium cepa L. Ecotoxicol. Environ. Saf. 153, 23–31. doi: 10.1016/j.ecoenv.2018.01.044
Molina, M., Asadian-Birjand, M., Balach, J., Bergueiro, J., Miceli, E., and Calderón, M. (2015). Stimuli-responsive nanogel composites and their application in nanomedicine. Chem. Soc. Rev. 44, 6161–6186. doi: 10.1039/C5CS00199D
Moon, J. W., Phelps, T. J., Fitzgerald, C. L., Lind, R. F., Elkins, J. G., Jang, G. G., et al. (2016). Manufacturing demonstration of microbially mediated zinc sulfide nanoparticles in pilot-plant scale reactors. Appl. Microbiol. Biotechnol. 100, 7921–7931. doi: 10.1007/s00253-016-7556-y
Nath, S., Kaittanis, C., Tinkham, A., and Perez, J. M. (2008). Dextran-coated gold nanoparticles for the assessment of antimicrobial susceptibility. Anal. Chem. 80, 1033–1038. doi: 10.1021/ac701969u
Neamtu, I., Rusu, A. G., Diaconu, A., Nita, L. E., and Chiriac, A. P. (2017). Basic concepts and recent advances in nanogels as carriers for medical applications. Drug Deliv. 24, 539–557. doi: 10.1080/10717544.2016.1276232
Nel, A. E., Mädler, L., Velegol, D., Xia, T., Hoek, E. M. V., Somasundaran, P., et al. (2009). Understanding biophysicochemical interactions at the nano-bio interface. Nat. Mater. 8, 543–557. doi: 10.1038/nmat2442
Pagano, L., Servin, A. D., De La Torre-Roche, R., Mukherjee, A., Majumdar, S., Hawthorne, J., et al. (2016). Molecular response of crop plants to engineered nanomaterials. Environ. Sci. Technol. 50, 7198–7207. doi: 10.1021/acs.est.6b01816
Pakrashi, S., Jain, N., Dalai, S., Jayakumar, J., Chandrasekaran, P. T., Raichur, A. M., et al. (2014). In vivo genotoxicity assessment of titanium dioxide nanoparticles by Allium cepa root tip assay at high exposure concentrations. PLoS ONE 9:e98828. doi: 10.1371/journal.pone.0087789
Palocci, C., Valletta, A., Chronopoulou, L., Donati, L., Bramosanti, M., Brasili, E., et al. (2017). Endocytic pathways involved in PLGA nanoparticle uptake by grapevine cells and role of cell wall and membrane in size selection. Plant Cell Rep. 36, 1917–1928. doi: 10.1007/s00299-017-2206-0
Pasupathy, K., Lin, S., Hu, Q., Luo, H., and Ke, P. C. (2008). Direct plant gene delivery with a poly(amidoamine) dendrimer. Biotechnol. J. 3, 1078–1082. doi: 10.1002/biot.200800021
Pérez-de-Luque, A. (2017). Interaction of nanomaterials with plants: what do we need for real applications in agriculture? Front. Environ. Sci. 5:12. doi: 10.3389/fenvs.2017.00012
Perrault, S. D., Walkey, C., Jennings, T., Fischer, H. C., and Chan, W. C. W. (2009). Mediating tumor targeting efficiency of nanoparticles through design - nano letters. Nano Lett. 9, 1909–1915. doi: 10.1021/nl900031y
Pokhrel, L. R., and Dubey, B. (2013). Evaluation of developmental responses of two crop plants exposed to silver and zinc oxide nanoparticles. Sci. Total Environ. 452–453, 321–332. doi: 10.1016/j.scitotenv.2013.02.059
Racuciu, M. (2012). Iron oxide nanoparticles coated with β-cyclodextrin polluted of Zea mays plantlets. Nanotechnol. Dev. 2:6. doi: 10.4081/nd.2012.e6
Rǎcuciu, M., and Creangǎ, D. E. (2009). Cytogenetical changes induced by β-cyclodextrin coated nanoparticles in plant seeds. Rom. Reports Phys. 54, 125–131.
Rad, F., Mohsenifar, A., Tabatabaei, M., Safarnejad, M. R., Shahryari, F., Safarpour, H., et al. (2012). Detection of Candidatus phytoplasma aurantifolia with a quantum dots fret-based biosensor. J. Plant Pathol. 94, 525–534. doi: 10.4454/JPP.FA.2012.054
Rai, V., Acharya, S., and Dey, N. (2012). Implications of nanobiosensors in agriculture. J. Biomater. Nanobiotechnol. 03, 315–324. doi: 10.4236/jbnb.2012.322039
Raliya, R., Franke, C., Chavalmane, S., Nair, R., Reed, N., and Biswas, P. (2016). Quantitative understanding of nanoparticle uptake in watermelon plants. Front. Plant Sci. 7:1288. doi: 10.3389/fpls.2016.01288
Ranjan, S., Dasgupta, N., and Lichtfouse, E. (2017). Nanoscience in Food and Agriculture 5 . Springer International Publishing. doi: 10.1007/978-3-319-58496-6
Rastogi, A., Tripathi, D. K., Yadav, S., Chauhan, D. K., Živčák, M., Ghorbanpour, M., et al. (2019). Application of silicon nanoparticles in agriculture. 3 Biotech 9:90. doi: 10.1007/s13205-019-1626-7
Roduner, E. (2006). Size matters: why nanomaterials are different. Chem. Soc. Rev. 35, 583–592. doi: 10.1039/b502142c
Ruotolo, R., Maestri, E., Pagano, L., Marmiroli, M., White, J. C., and Marmiroli, N. (2018). Plant response to metal-containing engineered nanomaterials: an omics-based perspective. Environ. Sci. Technol. 52, 2451–2467. doi: 10.1021/acs.est.7b04121
Sabo-Attwood, T., Unrine, J. M., Stone, J. W., Murphy, C. J., Ghoshroy, S., Blom, D., et al. (2012). Uptake, distribution and toxicity of gold nanoparticles in tobacco (Nicotiana xanthi) seedlings. Nanotoxicology 6, 353–360. doi: 10.3109/17435390.2011.579631
Saharan, V., Kumaraswamy, R. V., Choudhary, R. C., Kumari, S., Pal, A., Raliya, R., et al. (2016). Cu-chitosan nanoparticle mediated sustainable approach to enhance seedling growth in maize by mobilizing reserved food. J. Agric. Food Chem. 64, 6148–6155. doi: 10.1021/acs.jafc.6b02239
Santos, A. R., Miguel, A. S., Tomaz, L., Malh,ó, R., Maycock, C., Vaz Patto, M. C., et al. (2010). The impact of CdSe/ZnS quantum dots in cells of Medicago sativa in suspension culture. J. Nanobiotechnol. 8:24. doi: 10.1186/1477-3155-8-24
Schwab, F., Zhai, G., Kern, M., Turner, A., Schnoor, J. L., and Wiesner, M. R. (2016). Barriers, pathways and processes for uptake, translocation and accumulation of nanomaterials in plants - Critical review. Nanotoxicology 10, 257–278. doi: 10.3109/17435390.2015.1048326
Serag, M. F., Kaji, N., Gaillard, C., Okamoto, Y., Terasaka, K., Jabasini, M., et al. (2011). Trafficking and subcellular localization of multiwalled carbon nanotubes in plant cells. ACS Nano 5, 493–499. doi: 10.1021/nn102344t
Serag, M. F., Kaji, N., Habuchi, S., Bianco, A., and Baba, Y. (2013). Nanobiotechnology meets plant cell biology: carbon nanotubes as organelle targeting nanocarriers. RSC Adv. 3, 4856–4862. doi: 10.1039/c2ra22766e
Serik, O., Ainur, I., Murat, K., Tetsuo, M., and Masaki, I. (1996). Silicon carbide fiber-mediated DNA delivery into cells of wheat ( Triticum aestivum L.) mature embryos. Plant Cell Rep. 16:133–136 doi: 10.1007/BF01890853
Servin, A. D., and White, J. C. (2016). Nanotechnology in agriculture: next steps for understanding engineered nanoparticle exposure and risk. Nano Impact 1, 9–12. doi: 10.1016/j.impact.2015.12.002
Sharma, P., Bhatt, D., Zaidi, M. G. H., Saradhi, P. P., Khanna, P. K., and Arora, S. (2012). Silver nanoparticle-mediated enhancement in growth and Antioxidant status of Brassica juncea . Appl. Biochem. Biotechnol. 167, 2225–2233. doi: 10.1007/s12010-012-9759-8
Shen, C. X., Zhang, Q. F., Li, J., Bi, F. C., and Yao, N. (2010). Induction of programmed cell death in Arabidopsis and rice by single-wall carbon nanotubes. Am. J. Bot. 97, 1602–1609. doi: 10.3732/ajb.1000073
Shen, Z., Chen, Z., Hou, Z., Li, T., and Lu, X. (2015). Ecotoxicological effect of zinc oxide nanoparticles on soil microorganisms. Front. Environ. Sci. Eng. 9, 912–918. doi: 10.1007/s11783-015-0789-7
Shi, J., Yang, Y., Hu, T., Yuan, X., Peng, C., Chen, Y., et al. (2013). Phytotoxicity and accumulation of copper oxide nanoparticles to the Cu-tolerant plant Elsholtzia Splendens. Nanotoxicology 8, 179–188. doi: 10.3109/17435390.2013.766768
Simonin, M., Richaume, A., Guyonnet, J. P., Dubost, A., Martins, J. M. F., and Pommier, T. (2016). Titanium dioxide nanoparticles strongly impact soil microbial function by affecting archaeal nitrifiers. Sci. Rep. 6:33643. doi: 10.1038/srep33643
Song, U., Jun, H., Waldman, B., Roh, J., Kim, Y., Yi, J., et al. (2013). Functional analyses of nanoparticle toxicity: a comparative study of the effects of TiO2 and Ag on tomatoes ( Lycopersicon esculentum ). Ecotoxicol. Environ. Saf. 93, 60–67. doi: 10.1016/j.ecoenv.2013.03.033
Sun, D., Hussain, H. I., Yi, Z., Siegele, R., Cresswell, T., Kong, L., et al. (2014). Uptake and cellular distribution, in four plant species, of fluorescently labeled mesoporous silica nanoparticles. Plant Cell Rep. 33:1389–1402. doi: 10.1007/s00299-014-1624-5
Tanaka, Y., Kimura, T., Hikino, K., Goto, S., Nishimura, M., Mano, S., et al. (2012). “Gateway vectors for plant genetic engineering: overview of plant vectors, application for Bimolecular Fluorescence Complementation (BiFC) and multigene construction,” in Genetic Engineering - Basics, New Applications and Responsibilities , ed H. Barrera-Saldaña (Mexico: Universidad Autónoma de Nuevo León), 64. doi: 10.5772/32009
Tang, B. Z., Wang, Y., Podsiadlo, P., and Kotov, N. A. (2006). Biomedical applications of layer-by-layer assembly : from biomimetics to tissue engineering. Adv. Mater. 2136, 3203–3224. doi: 10.1002/adma.200600113
Tarafdar, J. C., Raliya, R., Mahawar, H., and Rathore, I. (2014). Development of zinc nanofertilizer to enhance crop production in pearl millet ( Pennisetum americanum ). Agric. Res. 3, 257–262. doi: 10.1007/s40003-014-0113-y
Torney, F., Trewyn, B. G., Lin, V. S. Y., and Wang, K. (2007). Mesoporous silica nanoparticles deliver DNA and chemicals into plants. Nat. Nanotechnol. 2, 295–300. doi: 10.1038/nnano.2007.108
Valenstein, J. S., Lin, V. S.-Y., Lyznik, L. A., Martin-Ortigosa, S., Wang, K., Peterson, D. J., et al. (2013). Mesoporous silica nanoparticle-mediated intracellular cre protein delivery for maize genome editing via loxP site excision. PLANT Physiol. 164, 537–547. doi: 10.1104/pp.113.233650
Valletta, A., Chronopoulou, L., Palocci, C., Baldan, B., Donati, L., and Pasqua, G. (2014). Poly(lactic-co-glycolic) acid nanoparticles uptake by Vitis vinifera and grapevine-pathogenic fungi. J. Nanoparticle Res. 16, 1917–1928. doi: 10.1007/s11051-014-2744-0
Verma, S. K., Das, A. K., Patel, M. K., Shah, A., Kumar, V., and Gantait, S. (2018). Engineered nanomaterials for plant growth and development: a perspective analysis. Sci. Total Environ. 630, 1413–1435. doi: 10.1016/j.scitotenv.2018.02.313
Vidyalakshmi, N., Thomas, R., Aswani, R., Gayatri, G. P., Radhakrishnan, E. K., and Remakanthan, A. (2017). Comparative analysis of the effect of silver nanoparticle and silver nitrate on morphological and anatomical parameters of banana under in vitro conditions. Inorg. Nano Metal Chem. 47, 1530–1536. doi: 10.1080/24701556.2017.1357605
Viswanath, B., and Kim, S. (2015). Influence of nanotoxicity on human health and environment: the alternative strategies. Rev. Environ. Contam. Toxicol. 240, 77. doi: 10.1007/398
Waalewijn-Kool, P. L., Ortiz, M. D., Lofts, S., and van Gestel, C. A. (2013). The effect of ph on the toxicity of zinc oxide nanoparticles to folsomia candida in amended field soil. Environ. Toxicol. Chem. 32, 2349–2355. doi: 10.1002/etc.2302
Wang, K., Drayton, P., Frame, B., Dunwell, J., and Thompson, J. (1995). Whisker-mediated plant transformation: an alternative technology. Vitr. Cell. Dev. Biol. Plant 31, 101–104. doi: 10.1007/BF02632245
Wang, P., Lombi, E., Zhao, F. J., and Kopittke, P. M. (2016). Nanotechnology: a new opportunity in plant sciences. Trends Plant Sci. 21:699–712. doi: 10.1016/j.tplants.2016.04.005
Wang, T., Bai, J., Jiang, X., and Nienhaus, G. U. (2012). Cellular uptake of nanoparticles by membrane penetration: a study combining confocal microscopy with FTIR spectroelectrochemistry. ACS Nano . 6:1251–1259. doi: 10.1021/nn203892h
Wang, Z., Xu, L., Zhao, J., Wang, X., White, J. C., and Xing, B. (2016). CuO nanoparticle interaction with arabidopsis thaliana: toxicity, parent-progeny transfer, and gene expression. Environ. Sci. Technol. 50, 6008–6016. doi: 10.1021/acs.est.6b01017
Whiteside, M. D., Treseder, K. K., and Atsatt, P. R. (2009). The brighter side of soils: Quantum dots track organic nitrogen through fungi and plants. Ecology 90, 100–108. doi: 10.1890/07-2115.1
Yao, K. S., Li, S. J., Tzeng, K. C., Cheng, T. C., Chang, C. Y., Chiu, C. Y., et al. (2009). Fluorescence silica nanoprobe as a biomarker for rapid detection of plant pathogens. Adv. Mater. Res. 79–82, 513–516. doi: 10.4028/www.scientific.net/AMR.79-82.513
Zhai, G., Walters, K. S., Peate, D. W., Alvarez, P. J. J., and Schnoor, J. L. (2014). Transport of gold nanoparticles through plasmodesmata and precipitation of gold ions in woody poplar. Environ. Sci. Technol. Lett. 1, 146–151. doi: 10.1021/ez400202b
Zhao, X., Meng, Z., Wang, Y., Chen, W., Sun, C., Cui, B., et al. (2017). Pollen magnetofection for genetic modification with magnetic nanoparticles as gene carriers. Nat. Plants 3, 956–964. doi: 10.1038/s41477-017-0063-z
Zheng, L., Hong, F., Lu, S., and Liu, C. (2005). Effect of Nano-TiO2 on strength of naturally aged seeds and growth of spinach. Biol. Trace Elem. Res. 104, 083–092. doi: 10.1385/BTER:104:1:083
Zhu, Z. J., Wang, H., Yan, B., Zheng, H., Jiang, Y., Miranda, O. R., et al. (2012). Effect of surface charge on the uptake and distribution of gold nanoparticles in four plant species. Environ. Sci. Technol. 46, 12391–12398. doi: 10.1021/es301977w
Keywords: nanomaterials, nanogels, plant nanobiotechnology, plant protection, nanosensors, advanced genetic engineering
Citation: Sanzari I, Leone A and Ambrosone A (2019) Nanotechnology in Plant Science: To Make a Long Story Short. Front. Bioeng. Biotechnol. 7:120. doi: 10.3389/fbioe.2019.00120
Received: 31 January 2019; Accepted: 07 May 2019; Published: 29 May 2019.
Reviewed by:
Copyright © 2019 Sanzari, Leone and Ambrosone. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY) . The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
*Correspondence: Alfredo Ambrosone, aambrosone@unisa.it
Disclaimer: All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers. Any product that may be evaluated in this article or claim that may be made by its manufacturer is not guaranteed or endorsed by the publisher.
Research Topics & Ideas
I f you’re just starting out exploring biotechnology-related topics for your dissertation, thesis or research project, you’ve come to the right place. In this post, we’ll help kickstart your research topic ideation process by providing a hearty list of research topics and ideas , including examples from recent studies.
PS – This is just the start…
We know it’s exciting to run through a list of research topics, but please keep in mind that this list is just a starting point . To develop a suitable research topic, you’ll need to identify a clear and convincing research gap , and a viable plan to fill that gap.
If this sounds foreign to you, check out our free research topic webinar that explores how to find and refine a high-quality research topic, from scratch. Alternatively, if you’d like hands-on help, consider our 1-on-1 coaching service .
Biotechnology Research Topic Ideas
Below you’ll find a list of biotech and genetic engineering-related research topics ideas. These are intentionally broad and generic , so keep in mind that you will need to refine them a little. Nevertheless, they should inspire some ideas for your project.
- Developing CRISPR-Cas9 gene editing techniques for treating inherited blood disorders.
- The use of biotechnology in developing drought-resistant crop varieties.
- The role of genetic engineering in enhancing biofuel production efficiency.
- Investigating the potential of stem cell therapy in regenerative medicine for spinal cord injuries.
- Developing gene therapy approaches for the treatment of rare genetic diseases.
- The application of biotechnology in creating biodegradable plastics from plant materials.
- The use of gene editing to enhance nutritional content in staple crops.
- Investigating the potential of microbiome engineering in treating gastrointestinal diseases.
- The role of genetic engineering in vaccine development, with a focus on mRNA vaccines.
- Biotechnological approaches to combat antibiotic-resistant bacteria.
- Developing genetically engineered organisms for bioremediation of polluted environments.
- The use of gene editing to create hypoallergenic food products.
- Investigating the role of epigenetics in cancer development and therapy.
- The application of biotechnology in developing rapid diagnostic tools for infectious diseases.
- Genetic engineering for the production of synthetic spider silk for industrial use.
- Biotechnological strategies for improving animal health and productivity in agriculture.
- The use of gene editing in creating organ donor animals compatible with human transplantation.
- Developing algae-based bioreactors for carbon capture and biofuel production.
- The role of biotechnology in enhancing the shelf life and quality of fresh produce.
- Investigating the ethics and social implications of human gene editing technologies.
- The use of CRISPR technology in creating models for neurodegenerative diseases.
- Biotechnological approaches for the production of high-value pharmaceutical compounds.
- The application of genetic engineering in developing pest-resistant crops.
- Investigating the potential of gene therapy in treating autoimmune diseases.
- Developing biotechnological methods for producing environmentally friendly dyes.
Biotech & GE Research Topic Ideas (Continued)
- The use of genetic engineering in enhancing the efficiency of photosynthesis in plants.
- Biotechnological innovations in creating sustainable aquaculture practices.
- The role of biotechnology in developing non-invasive prenatal genetic testing methods.
- Genetic engineering for the development of novel enzymes for industrial applications.
- Investigating the potential of xenotransplantation in addressing organ donor shortages.
- The use of biotechnology in creating personalised cancer vaccines.
- Developing gene editing tools for combating invasive species in ecosystems.
- Biotechnological strategies for improving the nutritional quality of plant-based proteins.
- The application of genetic engineering in enhancing the production of renewable energy sources.
- Investigating the role of biotechnology in creating advanced wound care materials.
- The use of CRISPR for targeted gene activation in regenerative medicine.
- Biotechnological approaches to enhancing the sensory qualities of plant-based meat alternatives.
- Genetic engineering for improving the efficiency of water use in agriculture.
- The role of biotechnology in developing treatments for rare metabolic disorders.
- Investigating the use of gene therapy in age-related macular degeneration.
- The application of genetic engineering in developing allergen-free nuts.
- Biotechnological innovations in the production of sustainable and eco-friendly textiles.
- The use of gene editing in studying and treating sleep disorders.
- Developing biotechnological solutions for the management of plastic waste.
- The role of genetic engineering in enhancing the production of essential vitamins in crops.
- Biotechnological approaches to the treatment of chronic pain conditions.
- The use of gene therapy in treating muscular dystrophy.
- Investigating the potential of biotechnology in reversing environmental degradation.
- The application of genetic engineering in improving the shelf life of vaccines.
- Biotechnological strategies for enhancing the efficiency of mineral extraction in mining.
Recent Biotech & GE-Related Studies
While the ideas we’ve presented above are a decent starting point for finding a research topic in biotech, they are fairly generic and non-specific. So, it helps to look at actual studies in the biotech space to see how this all comes together in practice.
Below, we’ve included a selection of recent studies to help refine your thinking. These are actual studies, so they can provide some useful insight as to what a research topic looks like in practice.
- Genetic modifications associated with sustainability aspects for sustainable developments (Sharma et al., 2022)
- Review On: Impact of Genetic Engineering in Biotic Stresses Resistance Crop Breeding (Abebe & Tafa, 2022)
- Biorisk assessment of genetic engineering — lessons learned from teaching interdisciplinary courses on responsible conduct in the life sciences (Himmel et al., 2022)
- Genetic Engineering Technologies for Improving Crop Yield and Quality (Ye et al., 2022)
- Legal Aspects of Genetically Modified Food Product Safety for Health in Indonesia (Khamdi, 2022)
- Innovative Teaching Practice and Exploration of Genetic Engineering Experiment (Jebur, 2022)
- Efficient Bacterial Genome Engineering throughout the Central Dogma Using the Dual-Selection Marker tetAOPT (Bayer et al., 2022)
- Gene engineering: its positive and negative effects (Makrushina & Klitsenko, 2022)
- Advances of genetic engineering in streptococci and enterococci (Kurushima & Tomita, 2022)
- Genetic Engineering of Immune Evasive Stem Cell-Derived Islets (Sackett et al., 2022)
- Establishment of High-Efficiency Screening System for Gene Deletion in Fusarium venenatum TB01 (Tong et al., 2022)
- Prospects of chloroplast metabolic engineering for developing nutrient-dense food crops (Tanwar et al., 2022)
- Genetic research: legal and ethical aspects (Rustambekov et al., 2023). Non-transgenic Gene Modulation via Spray Delivery of Nucleic Acid/Peptide Complexes into Plant Nuclei and Chloroplasts (Thagun et al., 2022)
- The role of genetic breeding in food security: A review (Sam et al., 2022). Biotechnology: use of available carbon sources on the planet to generate alternatives energy (Junior et al., 2022)
- Biotechnology and biodiversity for the sustainable development of our society (Jaime, 2023) Role Of Biotechnology in Agriculture (Shringarpure, 2022)
- Plants That Can be Used as Plant-Based Edible Vaccines; Current Situation and Recent Developments (İsmail, 2022)
As you can see, these research topics are a lot more focused than the generic topic ideas we presented earlier. So, in order for you to develop a high-quality research topic, you’ll need to get specific and laser-focused on a specific context with specific variables of interest. In the video below, we explore some other important things you’ll need to consider when crafting your research topic.
Get 1-On-1 Help
If you’re still unsure about how to find a quality research topic, check out our Research Topic Kickstarter service, which is the perfect starting point for developing a unique, well-justified research topic.
Find The Perfect Research Topic
How To Choose A Research Topic: 5 Key Criteria
How To Choose A Research Topic Step-By-Step Tutorial With Examples + Free Topic...
Research Topics & Ideas: Automation & Robotics
A comprehensive list of automation and robotics-related research topics. Includes free access to a webinar and research topic evaluator.
Research Topics & Ideas: Sociology
A comprehensive list of sociology-related research topics. Includes free access to a webinar and research topic evaluator.
Research Topics & Ideas: Public Health & Epidemiology
A comprehensive list of public health-related research topics. Includes free access to a webinar and research topic evaluator.
Research Topics & Ideas: Neuroscience
Research Topics & Ideas: Neuroscience 50 Topic Ideas To Kickstart Your Research...
📄 FREE TEMPLATES
Research Topic Ideation
Proposal Writing
Literature Review
Methodology & Analysis
Academic Writing
Referencing & Citing
Apps, Tools & Tricks
The Grad Coach Podcast
i want to write a research concept for my scholarship now i don’t know how to write it. my study area of interest is Master of Science in molecular biology. my proposed research topics are
1. use of genetic engineering in developing climate change resilient crops. 2. biotechnology in farming; improving drought resistance, pest and disease control
Hi, I am just seeing your comment and I am in the same boat. Did you end up choosing a research proposal? If yes, can you recommend some sites to use for research papers.
Submit a Comment Cancel reply
Your email address will not be published. Required fields are marked *
Save my name, email, and website in this browser for the next time I comment.
Submit Comment
- Print Friendly
Exploring the Role of Plant Biotechnology and Microbiology in Breeding for Climate-Resilient Crops: a focus on Rice, Wheat, Sorghum and Millets
Edited by: Shakeel Ahmad, PhD, Seed Center and Plant Genetic Resources Bank, Ministry of Environment, Water and Agriculture, Saudi Arabia Beatriz Andreo Jimenez , PhD, Wageningen University & Research, the Netherlands
Submission Status: Open | Submission Deadline: 20 March 2025
Meet the Guest Editors
About the collection.
- Collection Articles
Submission Guidelines
Shakeel Ahmad, PhD, Seed Center and Plant Genetic Resources Bank, Ministry of Environment, Water and Agriculture, Saudi Arabia
Articles will undergo the journal’s standard peer-review process and are subject to all the journal’s standard policies . Articles will be added to the Collection as they are published.
The Editors have no competing interests with the submissions which they handle through the peer-review process. The peer-review of any submissions for which the Editors have competing interests is handled by another Editorial Board Member who has no competing interests.
- Criminal Law Assignment Help
- Taxation Law Assignment Help
- Business Law Assignment Help
- Contract Law Assignment Help
- Civil Law Assignment Help
- Land Law Assignment Help
- Tort Law Assignment Help
- Company Law Assignment Help
- Employment Law Assignment Help
- Environmental Law Assignment Help
- Commercial Law Assignment Help
- Criminology Assignment Help
- Corporate Governance Law Assignment Help
- Constitutional Law Assignment Help
- Operations Assignment Help
- HRM Assignment Help
- Marketing Management Assignment Help
- 4 Ps Of Marketing Assignment Help
- Strategic Marketing Assignment Help
- Project Management Assignment Help
- Strategic Management Assignment Help
- Risk Management Assignment Help
- Organisational Behaviour Assignment Help
- Business Development Assignment Help
- Change Management Assignment Help
- Consumer Behavior Assignment Help
- Operations Management Assignment Help
- Public Relations Assignment Help
- Supply Chain Management Assignment Help
- Conflict Management Assignment Help
- Environmental Assignment Help
- Public Policy Assignment Help
- Childcare Assignment Help
- Business Report Writing Help
- Pricing Strategy Assignment Help
- Corporate Strategy Assignment Help
- Managerial Accounting Assignment Help
- Capital Budgeting Assignment Help
- Accounting Assignment Help
- Cost Accounting Assignment Help
- Financial Accounting Assignment Help
- Corporate Finance Assignment Help
- Behavioural Finance Assignment Help
- Financial Ethics Assignment Help
- Financial Management Assignment Help
- Financial Reporting Assignment Help
- Forensic Accounting Assignment Help
- International Finance Assignment Help
- Cost-Benefit Analysis Assignment Help
- Financial Engineering Assignment Help
- Financial Markets Assignment Help
- Private Equity and Venture Capital Assignment Help
- Psychology Assignment Help
- Sociology Assignment Help
- English Assignment Help
- Political Science Assignment Help
- Arts Assignment Help
- Civil Engineering Assignment Help
- Computer Science And Engineering Assignment Help
- Economics Assignment Help
- Climate Change Economics Assignment Help
- Java Assignment Help
- MATLAB Assignment Help
- Database Assignment Help
- PHP Assignment Help
- UML Diagram Assignment Help
- Web Designing Assignment Help
- Networking Assignment Help
- Chemistry Assignment Help
- Biology Assignment Help
- Nursing Assignment Help
- Biotechnology Assignment Help
- Mathematics Assignment Help
- Assignment Assistance
- Assignment Help Online
- Cheap Assignment Help
- Assignment Paper Help
- Solve My Assignment
- Do My Assignment
- Get Assignment Help
- Urgent Assignment Help
- Write My Assignment
- Assignment Provider
- Quality Assignment Help
- Make My Assignment
- Online Assignment Writers
- Paid Assignment Help
- Top Assignment Help
- Writing Assignment For University
- Buy Assignment Online
- All Assignment Help
- Academic Assignment Help
- Assignment Help Tutors
- Student Assignment Help
- Custom Assignment Writing Service
- English Essay Help
- Law Essay Help
- Management Essay Help
- MBA Essay Help
- History Essay Help
- Literature Essay Help
- Online Essay Help
- Plagiarism Free Essay
- Write My Essay
- Admission Essay Help
- TOK Essay Help
- Best Essay Writing Service
- Essay Assignment Help
- Essay Writers Online
- Professional Essay Writers
- Academic Writing
- Homework Help
- Dissertation Help
- University Assignment Help
- College Assignment Help
- Research Paper Writing Help
- Case Study Help
- Coursework Help
- Thesis Help
- PowerPoint Presentation Service
- Job Openings
Top 100 Biotechnology Dissertation Topics for the Year 2021
- September 14, 2021 September 14, 2021
Biotechnology is one of the major streams of science where students request for our reliable and time-tested assignment help from prestigious universities, colleges, and institutes around the globe. The subject helps us understand how we can effectively utilise biological systems, living organisms, or their parts to develop or create different types of products.
GET HELP INSTANTLY Place your order to get best assignment help
(since 2006)
Apart from genetics, bioengineering and research, the subject offers decent career options in industrial sectors like textiles, food, agriculture, pharmaceutical and animal husbandry.
Introduction
Modern biotechnology has been credited with breakthrough innovations in the field of product development and technologies to help us develop a cleaner and more sustainable world. It is primarily because of biotechnology; we have progressed towards the development of more efficient industrial manufacturing base. Besides, it is helping in the production of cleaner energy, feed more hungry people without leaving much of our environmental footprint, and help mankind combat rare and debilitating diseases.
Our assignment writing services in the field of biotechnology cover all types of subject topics that test and vindicate the skill sets of the students before awarding them with their respective degrees. We help students successfully pass their syllabus in all forms of biotechnology courses. These include medical biotechnology (red), environmental biotechnology (green), marine biotechnology (blue) and industrial biotechnology (white).
What are We Expecting to Gain from All these Efforts?
Our sole objective of preparing this marathon list of top 100 biotechnology assignment topics is to help students decide upon effective time management skills. We have seen an immense numbers of cases where while exploring online assignment help related to topic selection, exploration of information sources, and citing them in correct reference order, students get stuck at different stages. Amongst them, most of the students find it difficult even to pass their topic selection dilemma. That is where we contribute to our efforts to make things easy for the biotech students right in one go. We help our students save time and energy, so that they can prudently use the assigned time to prepare the content of their assignment around the best topics.
Are you keen to master your dissertation writing skills in just a couple of weeks? Read the below amazing article and do not miss the golden opportunity to learn from the experts absolutely for free!
Must read: wish to master dissertation skills in 2 weeks learn from the experts here, top 100 biotechnology dissertation topics trending in the year 2021.
We have prepared the list of top 100 most recommended dissertation topics prepared by our research experts. They have ensured to provide a comprehensive list of topics that are covering all the dimensions of the subject. We fully hope that the list would cover all your dissertation help requirements. So, let us begin with the prepared list of topics one by one –
- Effective management of renewable energy technology to promote a village
- The production of ethanol with the help of molasses as well as its effluent treatment
- Different methods and aspects of evapotranspiration
- The scattering parameters of the circulator biotechnology
- The inactivation of the mammalian TLR2 through an inhibiting antibody
- Number of proteins through Mycobacterium tuberculosis
- The recognition and classification of the genes shaping the plant responses to salinity and drought
- The segment of small signing molecules in the responses of plants to salinity and drought
- Genetic improvement of the plant lenience to salinity and drought
- Pharmacogenomics of the drug transporters
- Pharmacogenomics of the anti-cancer drugs
- Pharmacogenomics of the anti-hypertensive drugs
- Indels genotyping of the African populations
- Y-chromosome genotyping of the African populations
- Profiling of the DNA isolated from the historical crime scenes: Discuss in terms of South African Innocence Project
- Nanotechnology methods in terms of DNA isolation
- Nanotechnology applications in terms of DNA genotyping
- Recognizing heavy metal tolerant along with sensitive genotypes
- Features of genes that participate in the process of heavy metal tolerance
- DNA authentication of the animal species through raw meat products reared commercially
- Molecular based technology in terms of rapid identification and detection of the food borne pathogens with respect to complex food systems
- Making an assessment of cancer specific peptides for successful implementations in the field of cancer diagnosis
- Quantum dot-based detection system development with respect to successful breast cancer diagnosis
- Targeted delivery of the embelin to the cancer cells
- Accessing the role of novel quinone compounds to perform as anti-cancer agents
- Therapeutic approaches to the treatment of HIV and the role of nanotechnology in it
- An assessment of the medicinal value of the natural antioxidants
- An indepth study of the structure of the COVID spike proteins
- An assessment of the immune response of the stem cell therapy
- The use of CRISPR-Cas9 technology for the purpose of genome editing
- Tissue engineering and the drug delivery with the application of Chitosan
- An assessment of therapeutic effects of the cancer vaccines
- Utilization of PacBio sequencing with respect to genome assembly of the model organisms
- Studying the relationship between the mRNA suppression and its impact on the expansion of the stem cell
- Utilizing biomimicry for the identification of the tumor cells
- The sub-classification and characterization of the Yellow enzymes
- The production of the hypoallergenic fermented foods
- The production of the hypoallergenic milk
- The purification process of the thermostable phytase
- Bioconversion of the cellulose to successfully yield the products that are industrially significant
- The examination of the gut microbiota in the model organisms
- The utilization of the fungal enzymes in the production of chemical glue
- An examination of the inhibitors of exocellulase and endocellulase
- Discuss the utility of microorganisms in the recovery of shale gas
- Discuss the in-depth study of the procedure of natural decomposition
- Discuss the process of recycling the bio-wastes
- Enhanced bio-remediation for the cases of oil spills
- The process of gold biosorption with the help of cyanobacterium
- Maintaining a healthy balance between the biotic and the abiotic factors with the help of biotechnological tools
- Labeling the level of mercury in fish with the help of markers
- Exploring out the biotechnological potential of the Jellyfish related microbiome
- What is the potential of marine fungi in the efforts to degrade polymers and plastics?
- Discuss the biotechnological potential that one can fetch out of dinoflagellates
- Tracing out endosulfan residues with the application of biotechnology in the field of agricultural products
- The development of the ELISA technique for the identification of crop viruses
- Boosting the quality of drinking water with the help of E.coli consortium
- The characterization of E.coli isolation from the feces of the zoo animals
- Improving the resistance of the crops against the invasion of the insects
- Reducing the spending on agriculture with the help of effective bio-tools
- What are the most effective steps to reduce soil erosion with the utility of tools derived from biotechnology?
- How biotechnology can help in the improvement the levels of vitamin in GM foods?
- Improving the delivery of pesticide with the help of biotechnology
- Comparing folate biofortification in different kinds of corps
- Discuss the photovoltaic-based production of the ocean crops
- How the application of nanotechnology to improve the activities of the agricultural sector?
- Examining the mechanisms of water stress tolerance in the model plants
- Testing and production of the human immune boosters in the experimental organisms
- Comparing genomic analysis with the utility of tools meant for bioinformatics
- Arabinogalactan protein sequencing and its utility in computational methods
- Evaluating and interpreting gut microbiota in the model organisms
- Different techniques of protein purification: A comparative analysis
- Diagnosing microbes and their role in o ligonucleotide micro-arrays
- The application of different techniques in the field of biomedical research comprising micro-arrays technology
- The application of microbial consortium in producing the greenhouse effect
- Computational assessment of various proteins accessed from marine microbiota
- E.coli gene mapping with the application of various microbial tools
- Enhancing the strains of cyanobacterium with the help of gene sequencing
- Computational assessment and description of the crystallized proteins present in nature
- mTERF protein and its application to terminate the transcription of mitochondrial DNA in algae
- Reverse phase column chromatography and its application in separating proteins
- The study of various proteins present within Mycobacterium leprae
- An assessment of the strategies that are ideally suitable for successful cloning of RNA
- Discuss the common failures of biotechnology in saving the ecology and the environment
- Is there a way to make the medicinal plants free of pests? Discuss
- What are the harms imposed by pest resistant corps on humans and birds?
- What are the diverse fields of biotechnology that still remain unexplored in terms of research?
- What is the future of biotechnology in the field of medicine?
- The application of recombinant DNA technology in the invention of new forms of medicine
- Why is the strain of bacteria used to create vaccine with the help of biotechnology?
- How biotechnology can help in the creation of medicines that are more resistant towards the mutating forms of viruses and bacteria?
- Can there be a permanent cure for cancer in the future? How biotechnology can play a decisive role in it?
- Why it is critical for the students to effectively remember the DNA coding in the field of biotechnology?
- How one can make hybrid seeds with the help from biotechnology?
- How one can generate pest resistant seeds and what are their benefits in the end yielding in agriculture?
- Discuss bio-magnification and its impact on ecology
- What are the reasons due to which the ecologists disapprove the usage of pest resistant seeds, despite their usage in the field of agriculture?
- How biotechnology positively influenced the lives of farmers in the developing economies?
- How biotechnology functions to increase in yield of the crop plants?
- Discuss the role of biotechnology in boosting the output of seasonal crops
- Are there adverse effects of medicines in pharmacology when manufactured with biotechnological principles? Throw some light on the question with real-life cases
Now with that, we have reached the end of this list and fully hope that it would have served the purpose of topic selection requirements. Besides, the inclusion of biotechnology assignment topics has been done in such a manner that it can help us out with our needs related to different other assignment writing formats as well. For instance, all our topic selection requirements related to case study help , essay help , research paper writing help or thesis help can also be met with the topics in the above-mentioned list.
Are you facing the heat of topic selection dilemma in your biology assignment homework? Check the below link to rely upon the topic list that the most respected experts recommend.
Must read: top 100 biology dissertation topics for the year 2021.
Biotechnology is a subject that is meant to offer a plethora of research prospects. A successful completion of course in one or more streams of biotechnology will ensure job placement opportunities in different research and development companies dedicated to the field. The objective of recommending this list is to help you make the right topic selection in less amount of time and dedicate more time to assignment research, and adequate content writing. After all, going an extra mile in terms of efforts will ensure that the final submission is good enough to help you earn the grades that can help you beat the competition.
If you have liked our recommended list of 100 biotechnology topics, then we invite you to reach our paid assignment help to unburden all the biotech assignment worries onto the shoulders of the most trusted professional assignment writers. Reach biotechnology assignment help to learn how the most trusted online homework help agency has helped thousands of biotechnology students to skyrocket to better career opportunities in the last 15 years. It is the time to step-in and reap the benefits from what the best in business has to offer!
We have 48 Latest Plant Biology PhD Research Projects
Biological Sciences
All locations
Institution
All Institutions
PhD Research Projects
All Funding
Latest Plant Biology PhD Research Projects
Root dynamics and ecosystem function, phd research project.
PhD Research Projects are advertised opportunities to examine a pre-defined topic or answer a stated research question. Some projects may also provide scope for you to propose your own ideas and approaches.
Funded PhD Project (European/UK Students Only)
This project has funding attached for UK and EU students, though the amount may depend on your nationality. Non-EU students may still be able to apply for the project provided they can find separate funding. You should check the project and department details for more information.
Priming of long-term defence against insect pests in forest tree
Competition funded phd project (students worldwide).
This project is in competition for funding with other projects. Usually the project which receives the best applicant will be successful. Unsuccessful projects may still go ahead as self-funded opportunities. Applications for the project are welcome from all suitably qualified candidates, but potential funding may be restricted to a limited set of nationalities. You should check the project and department details for more information.
Structural and functional basis of LPS transport
Engineering physiological responses in plants to enhance flood tolerance, understanding oceanic photosynthesis, a new green revolution: regulation of wheat growth in response to heat and drought, breaking rhododendron: understanding the drivers of rhododendron success, disparities in divergence: the genomics of large vs small genera, characterising the 3d distribution of canopy chlorophyll content using dual-wavelength laser scanning to better quantify vegetation health, crossed wires: examining the influence of nutrient colimitation on phytoplankton ecophysiology, taking control - can phytoplankton increase nutrient uptake by manipulating their microenvironment, impacts of floral nutritional loss on pollinator community interactions, understanding how production of dimethylsulfoniopropionate by plants affects global sulfur cycling (miller_ubio25aries), the role of zinc in the adaptation of diatoms to conditions of polar oceans (mock_uenv25aries), how do plants balance the pros and cons of staying connected to their neighbours, funded phd project (students worldwide).
This project has funding attached, subject to eligibility criteria. Applications for the project are welcome from all suitably qualified candidates, but its funding may be restricted to a limited set of nationalities. You should check the project and department details for more information.
FindAPhD. Copyright 2005-2024 All rights reserved.
Unknown ( change )
Have you got time to answer some quick questions about PhD study?
Select your nearest city
You haven’t completed your profile yet. To get the most out of FindAPhD, finish your profile and receive these benefits:
- Monthly chance to win one of ten £10 Amazon vouchers ; winners will be notified every month.*
- The latest PhD projects delivered straight to your inbox
- Access to our £6,000 scholarship competition
- Weekly newsletter with funding opportunities, research proposal tips and much more
- Early access to our physical and virtual postgraduate study fairs
Or begin browsing FindAPhD.com
or begin browsing FindAPhD.com
*Offer only available for the duration of your active subscription, and subject to change. You MUST claim your prize within 72 hours, if not we will redraw.
Create your account
Looking to list your PhD opportunities? Log in here .
Filtering Results
- Search Choose the search context Search Search for: Start search Staff and BOKUweb content Staff only
- DE / EN Wechseln zu Deutsch
- Master Thesis
- Department of Agrobiotechnology, IFA-Tulln
- Institute of Biotechnology in Plant Production
This page is available under these URLs:
- https://boku.ac.at/en/ifa-tulln/institut-fuer-biotechnologie-in-der-pflanzenproduktion/masterarbeiten
- https://short.boku.ac.at/59w394
Master thesis options | plant breeding
.... in the the BOKU thesis database !
We offer master thesis connected to our current research projects Master thesis topics are available in the areas: plant breeding, plant-pathogen-interaction, genetics of disease resistance, plant-biotechnology, and related fields. Thesis topics could be of interest to students in agricultural science (e.g. plant sciences, agricultural biology, phytomedicine) and biotechnology (plant biotechnology).
Do you have a passion for plants? Do you like working outdoors? Then contact us: we continuously have topics in plant breeding for master thesis available.
- Evaluation of experimental populations (bread wheat, durum wheat) for resistance to Fusarium head blight in field trials.
- Validation of candidate disease resistance genes in a TILLING population of wheat.
- Genomic Prediction of performance, quality and resistance traits in winter wheat.
- Genetic analysis and breeding for common bunt ( Tilletia caries ) resistance in winter wheat for organic farming.
Interested?
Please contact one of the workgroup leaders:
- Prof. Hermann Bürstmayr (01 47654 97102)
- Prof. Marc Lemmens (01 47654 97158)
- Dr. Barbara Steiner (01 47654 97105)
- Dr. Sebastian Michel (01 47654 97105)
- Bibliography
- More Referencing guides Blog Automated transliteration Relevant bibliographies by topics
- Automated transliteration
- Relevant bibliographies by topics
- Referencing guides
Top 50 Research Topics in Biotechnology
Table of Contents
Biotechnology
Research in biotechnology can helps in bringing massive changes in humankind and lead to a better life. In the last few years, there have been so many leaps, and paces of innovations as scientists worldwide worked to develop and produce novel mRNA vaccinations and brought some significant developments in biotechnology. During this period, they also faced many challenges. Disturbances in the supply chain and the pandemic significantly impacted biotech labs and researchers, forcing lab managers to become ingenious in buying lab supplies, planning experiments, and using technology for maintaining research schedules.
The Biotech Research Technique is changing
How research is being done is changing, as also how scientists are conducting it. Affected by both B2C eCommerce and growing independence in remote and cloud-dependent working, most of the biotechnology labs are going through some digital transformations. This implies more software, automation, and AI in the biotech lab, along with some latest digital procurement plans and integrated systems for various lab operations.
Look at some of the top trends in biotech research and recent Biotechnology Topics that are bringing massive changes in this vast world of science, resulting in some innovation in life sciences and biotechnology ideas .
We share different job or exam notices on Labmonk Notice Board . You can search “ Labmonk Notice Board ” on google search to check out latest jobs of your field.
IMAGES
VIDEO
COMMENTS
Expression of Animal Proteins in Plants. Neil E. Hoffman. Gijs A Kleter. Kathleen L Hefferon. 8,906 views. 5 articles. This section explores all branches of plant biotechnology, addressing the attempts of modern technologies to satisfy increasing demands for crop production.
Biotechnology, at its core, involves the application of biological systems, organisms, or derivatives to develop technologies and products for the benefit of humanity. The scope of biotechnology research is broad, covering areas such as genetic engineering, biomedical engineering, environmental biotechnology, and industrial biotechnology.
Abstract. Biotechnology explores the metabolic properties of living organisms for the production of valuable products of a very different structural and organizational level. Plant serves as an important source of primary and secondary metabolites used in pharmacy, biotechnology, and food technology. Plant biotechnology has gained importance in ...
Not just in terms of prospects, but also in terms of wage packages for biotechnology experts. Top 150 Research Proposal Topics and more about Biotechnology for 2022 from the best academic expert dissertation writers of AHECounselling. Plant, Pharmacogenetics, Forensic DNA, Food, Proteomics Biotechnology.
endangered world. Marc Van Montagu 1. 1 VIB-International Plant Biotechnology Outreach, Ghent University, Ghent, Belgium. Abstract. This paper draws on the importance of science-based agriculture ...
Plant Biotechnology Journal presents research at the forefront of applied plant science and molecular plant sciences. Published in partnership with the Society for Experimental Biology (SEB) and the Association of Applied Biology (AAB) it is dedicated to showcasing original research and insightful reviews by renowned researchers in the field of plant biotechnology.
3.2.4 Other Topics in Population and Quantitative Genetics 55 3.2.5 The Value of a Plant Variety Depends on Many Traits 56 3.2.6 Varieties Must Be Adapted to Environments 56 3.2.7 Plant Breeding Is a Numbers Game 57 3.2.8 Plant Breeding Is an Iterative and Collaborative Process 57 3.2.9 Diversity, Adaptation, and Ideotypes 58
An analysis of patent documents reveals a trend of increasing interest in functional food innovations that may aid future decision-making in research, business and policymaking. Maima Matin ...
NGs are defined as nano-sized ionic and non-ionic hydrogels made of synthetic or natural polymeric chains, chemically or physically cross-linked (Molina et al., 2015; Neamtu et al., 2017). NGs possess a high water content (70-90% of the entire structure), a high degree of porosity and high load capacity.
If you're just starting out exploring biotechnology-related topics for your dissertation, thesis or research project, you've come to the right place. In this post, we'll help kickstart your research topic ideation process by providing a hearty list of research topics and ideas, including examples from recent studies.. PS - This is just the start…
Edited by: Shakeel Ahmad, PhD, Seed Center and Plant Genetic Resources Bank, Ministry of Environment, Water and Agriculture, Saudi Arabia Beatriz Andreo Jimenez, PhD, Wageningen University & Research, the Netherlands. Submission Status: Open | Submission Deadline: 20 March 2025. Rice is calling for submissions to our Collection on Exploring the Role of Plant Biotechnology and Microbiology in ...
18. Fees. aprox. €540 per year View detail of the PhD's fees. Languages in which the thesis may be written. English, Catalan, Spanish. Organising universities and institutions. Universitat Autònoma de Barcelona. Associated departments or institutes. Department of Animal Biology, Plant Biology and Ecology.
Genetic improvement of the plant lenience to salinity and drought. Pharmacogenomics of the drug transporters. Pharmacogenomics of the anti-cancer drugs. Pharmacogenomics of the anti-hypertensive drugs. Indels genotyping of the African populations. Y-chromosome genotyping of the African populations.
Monash University Malaysia School of Science. Over 100+ Scholarships Available. Scholarships include the Graduate Research Excellence Scholarships, Tuition Waiver Scholarships, Global Excellence and Mobility Scholarships. Read more. Funded PhD Programme (Students Worldwide) International PhD Programme. More Details.
3 Plant Biotechnology; 2 Agriculture Dairy and Animal Science. next > Year Completed. 406 2020 - 2024; 39 2012 - 2019; Language. 458 English; Departments in this University. 05Horticulture [20] 06Genetics and Plant Breeding [37] 06 Sericulture [11] 07 Seed Science and Technology [22] ...
University of Edinburgh School of Biological Sciences. The final form (or shape) of a plant is a key determinant of fitness, and in our crops this translates to yield and quality. Read more. Supervisor: Dr A Richardson. 25 November 2024 PhD Research Project Funded PhD Project (Students Worldwide) More Details.
We offer master thesis connected to our current research projects Master thesis topics are available in the areas: plant breeding, plant-pathogen-interaction, genetics of disease resistance, plant-biotechnology, and related fields. Thesis topics could be of interest to students in agricultural science (e.g. plant sciences, agricultural biology, phytomedicine) and biotechnology (plant ...
List of dissertations / theses on the topic 'Plant biotechnology'. Scholarly publications with full text pdf download. Related research topic ideas.
Look at some of the top trends in biotech research and recent Biotechnology Topics that are bringing massive changes in this vast world of science, resulting in some innovation in life sciences and biotechnology ideas. Development of vaccine: Development of mRNA has been done since 1989 but has accelerated to combat the pandemic. As per many ...
Research Topic For Biotechnology 2023. Sr. No. Research Topic. Check Thesis. 1. Identification of genetic locus associated with resistance to brown planthopper. Download. 2. Identifying genes expressed during water stress in rice cv Nootripathu roots.