phd thesis topics in oral medicine

•   TARA
• School of Dental Sciences
• Oral Medicine

Oral Medicine (Theses and Dissertations)

Titles Authors Date of Publication Subjects Sponsor

Search within this collection:

Recent Submissions

Oral leukoplakia - an investigation of its microbiome and of the association of clinical and microbial features with the degree of dysplasia 

Aspects of Dose Optimisation and Diagnostic Efficacy Relating to Dental Cone Beam Computed Tomography (CBCT) 

Functional analysis of the TLO gene family in Candida albicans and Candida dubliniensis 

Molecular epidemiological typing of emerging methicillin-resistant Staphylococcus aureus strains in the community, among livestock and in healthcare facilities in Ireland, 2001-2015 

The role of hyphae and hypha-associated genes in the pathogenesis of Candida dubliniensis 

A comparison of various methods of assessing salivary flow in normal and xerostomic subjects 

Comparative analysis of stress responses in C. albicans and C. dubliniensis 

Comparative growth analysis of Candida dubliniensis and Candida albicans in vitro and in selected infection models 

Comparative genetic analysis of nosocomial methicillin-resistant Staphylococcus aureus populations in Ireland 1971-2004 

Development of long-term practical solutions to the universal problem of biofilm contamination of dental unit waterlines 

Comprehensive molecular characterisation of endemic and sporadic methicillin resistant Staphylococcus aureus recovered in Irish hospitals 

An investigation into the relative adhesion of Candida dubliniensis and Candida albicans to human cells and extracellular matrix proteins 

A population structure analysis of Candida dubliniensis using multilocus sequence typing and an investigation of the molecular mechanism(s) of clade-specific resistance to 5-fluorocytosine 

Biocompatibility of non-precious dental casting alloys : development of novel testing mechanisms 

The strengthening of resin cemented dental ceramic materials 

The telomere-associated (TLO) genes of Candida dubliniensis 

Effects of montmorillonite clay addition on the compressive fracture strength and wear resistance of glass-ionomer restoratives 

Molecular typing of Methicillin-resistant and Methicillin-susceptible Staphylococcus aureus and Coagulase-negative staphylococci recovered in Irish hospitals and characterisation of SCCmec and SCCmec-containing composite islands 

Molecular characterisation of Staphylococcus aureus and Staphylococcus epidermidis populations from healthy and diseased oral implant and natural tooth sites in a cohort of patients with periimplantitis 

High-throughput DNA microarray characterisation and molecular analysis of resistance to mupirocin, fusidic acid and linezolid in Methicillin-Resistant Staphylococcus aureus : populations in Irish hospitals 1971-2010 

Eastman Dental Institute

Current PhD projects

There is a variety of research activity taking place at the Institute. Below is a list of research areas, each with details of project titles within that area suitable for study at MPhil/PhD level. To discuss any potential MPhil/PhD further, please do not contact potential supervisors directly. All enquiries should be directed to the Research Student Administrator at  [email protected] .

You can also browse PhD projects by supervisor .

Project titles:

Project titles

• Research departments
• Current students
• Student testimonies
• Recent papers
• Research at UCL
• Why research with us?

Student testimonial

Sign up to our newsletter

e-Publications@Marquette

Home > Dentistry > dissertations

School of Dentistry Dissertations and Theses

The School of Dentistry Dissertations and Theses Series is comprised of dissertations and theses authored by Marquette University's School of Dentistry doctoral and master's students.

Theses/Dissertations from 2024 2024

IN VITRO COMPARISON OF CELLULAR CYTOXICITY OF CONVENTIONAL VS. CAD/CAM DENTURE BASE MATERIALS , Zainab Hill Albasry

A COMPUTATIONAL FLUID DYNAMICS ANALYSIS COMPARING IRRIGATION WITHIN COMPLEX ROOT CANAL ANATOMY , Madeleinne Fern

Impact of Learning-Style-Based Education on Student Performance and Perception in Preclinical Endodontics: Part II , Rebecca Flaugher

PREEMPTIVE ANALGESIA AND PAIN AFTER PERIODONTAL AND IMPLANT- RELATED PROCEDURES: A SYSTEMATIC REVIEW AND META-ANALYSIS , Christos Gousias

Sleeveless guides are more accurate than sleeved guides: An in vitro study , Jenna Hang

RELIABILITY OF THE CVMS METHOD TO ASSESS THE CRANIOFACIAL GROWTH SPURT , Holly Ingersoll

Morphology of the Cranial Base of Untreated Class I and Class II Subjects , Ethan Just

Performance and Preference of Rotary Files by Pre-Doctoral Dental Students at Marquette School of Dentistry , Morgan Elizabeth McCall

Contribution of Dentoalveolar Heights on Facial Heights in Class I and Class II Untreated Subjects , Mira Bharat Suvagia

ORTHODONTIC LOAD QUANTIFICATION LEVELING A DEEP CURVE OF SPEE WITH DIFFERENT ARCHWIRE DESIGNS , Ahmed Youssef

Theses/Dissertations from 2023 2023

Effects of Thermocycling and Hydrolytic Aging on The Flexural Strength of Additively Manufactured Restorative Materials , Steven Mustafa Abu Al Tamn

LONG-TERM ASSESSMENT OF SKELETAL AND DENTAL ASYMMETRY AFTER CONVENTIONAL AND MINI-SCREW ASSISTED RAPID PALATAL EXPANSION , Brett Barton

Maxillary and Mandibular Incisor and Molar Dentoalveolar Heights in Untreated Subjects Presenting Class I and Class II Malocclusion , Samantha Zavada Cardinal

Factors Associated with Extraction Versus Non-Extraction Treatment Among Orthodontic Patients at Marquette University , Kelley Dentino

Short and Long-Term Effects of Conventional and Miniscrew-Assisted Rapid Palatal Expansion on Hard Tissues Using Voxel-Based Superimposition of Serial CBCTs , Isaac R. Empson

The Effect of Endodontic Access Cavity Designs on Crack Propagation of Mandibular Molars , Colin Kodama

Alveolar Bone Remodeling In Response to Orthodontic Tooth Movement , Matthew Raymond McGrady

A Digital Assessment of Centric Relation Precision , Christine Roenitz

The Influence of the Digitization Method on the Assessment of Accuracy and Reliability of Implant Placements , Ajitesh Singh

Immediate Postoperative Dimensional Changes Following Implant Placement , Juan Felipe Valencia Rincon

The Influence of Peri-Cervical Dentin Conservation on the Propagation of Cracks in Mandibular Molars , Hassanain Zaheer

Theses/Dissertations from 2022 2022

Edge-Chipping and Translucency Comparison Among Lithium Silicate-Based Ceramics , Essa Abdullah Alghamdi

Associations Between the Movement of Hard and Soft Tissues After Orthodontic Proclination of Incisors , Scott Beard

Evaluation of Damon PSL and Conventional MBT Brackets in Leveling and Alignment Efficiency , Jacob Beckstrand

Activated Charcoal Versus a Chemical Whitening Agent: Effect on Human Enamel , Hien Thai Doan

Color Characterization of Color Changing Orthodontic Adhesives , Megan Fried

Influence of Free-End Distal Extension on the Accuracy of Guided Implant Placement: An In Vitro Study , Geoffrey Ganzman

Influence of Multiple Root-End Surgery or Root Amputation on Root Surface Stress Distribution , John Curtis Jurkas

Autoignition and Sooting Characteristics of Iso-Octane and Ethanol in an Optical Rapid Compression Machine , Richard John Kempf

The Effect of Tray Design and Impression Material Consistencies on Accuracy of Complete Arch Implant Supported Fixed Dental Prostheses Master Casts , lujain Kurdi

Immediate Postoperative Dimensional Changes Following Guided Bone Regeneration , Morvarid Monfaredzadeh

The Accuracy and Sensitivity of ABO Electronic Cast Radiographic Program ORTHOSHARE 360 Compared to Manual Measurements , Lisa Nguyen

Identifying Optimal Composite Resin Depth to Maximize Fracture Resistance when Restoring Immature Endodontically Treated Teeth , David Poe

Mechanism of Mechanical Vibration in Enhancing Orthodontic Retention- Analysis of Global Gene Expression , Shuwei Wang

Theses/Dissertations from 2021 2021

In Vitro Study to Analyze Reverse Torque Values of Prosthetic Screws with Multiple Loosening/Tightening Preload Cycles , Amira Alhameed

Effects of Cleaning Agents on the Properties of Two Different Thermoplastic Retainer Materials , Jennifer Brehove

Correction of Excessive Gingival Display: Lip Repositioning with/without Myotomy , Austin Michael Dodge

The Influence of the Operator Experience on the Accuracy of Implant Placement: An In Vitro Study , Jeffrey Garcia

Root-End Surgery or Nonsurgical Retreatment: Are There Differences in Long Term Outcome? , Enida Haxhia

Mechanism of Mechanical Vibration in Enhancing Orthodontic Retention , Brent A. Ito

The Incidence of Root Canal Therapy or Extraction after Orthodontic Treatment: A Ten-Year Retrospective Study , Thomas Korte

Outcomes of Nonsurgical Root Canal Therapy Completed in Children Aged 6-13 Years , Lauren M. Loney

Comparing Orthodontic Debonding Aerosol Production with Various High-Volume Evacuation Systems , Eric Moe

Bending and Phase Transformation Properties of a Force Gradient Nickel-Titanium Orthodontic Wire , Brinda Shah

Effects of Fluoride on Corrosion Properties of Orthodontic Retention Wires , John J. Simindinger

Shear Bond Strength Characteristics on Surface Treatment Modalities of CAD-CAM Resin Based Core Materials , Nikita Sinha

Theses/Dissertations from 2020 2020

Oral Health and Quality of Life: A Clinic-Based Sample , Kinan M. Al-Bitar

Peri-Implantitis Risk Prediction Using a Computer Based Periodontal Risk Calculator Tool: A Retrospective Study , Walaa AL Zaibak

Assessment of 3D Facial Scan Integration in 3D Digital Workflow Using Radiographic Markers and Iterative Closest Point Algorithm , Mohamed Elshewy

Outcomes of Primary Endodontic Therapy in Medicaid Enrollees , Timothy Gainey

Corrosion Properties of Various Orthodontic Fixed Retention Wires , Tara Lynn Groen

Anatomical Considerations for Miniplate-Anchored Maxillary Protraction in Children with Unilateral Cleft Lip and Palate , Jared Holloway

Efficacy of Invisalign: A Retrospective Case Series of Intrusion, Extrusion, and Rotation with Trend Analysis , Kirsten Karkow

The Effect of Mechanical Vibration on Alveolar Bone Following Experimental Periodontitis: A Time Course Study , Joshua Murphy

Accuracy of Merging Scans of Definitive Fixed Prosthodontic Impressions to Obtain Single, Accurate Digitized Master Casts , Ossama Raffa

Tensile Strength of Elastomeric Ligature Ties Stretched Over Large and Small Orthodontic Brackets , Golden Shiloh

Influence of Progressive vs. Minimal Canal Preparations on the Fracture Resistance of Mandibular Molars: A Finite Element Analysis , Michael Smoljan

Impact of Delayed Completion of Previously Initiated Therapy and Provider Type on Outcomes of Root Canal Treatment , Igor Sulim

Theses/Dissertations from 2019 2019

The Cytotoxicity Effect of Silver Solder Materials on Human Periodontal Ligament Fibroblast Cells , Joseph Jeffrey Curry

An in Vitro Study of Surface Alterations to PEEK and Titanium and Its Effect Upon Human Gingival Fibroblasts , Maryam Gheisarifar

Effect of Heat-Treatment Time on Bending Properties of Cobolt-Chromium Orthodontic Wires , Melanie Hammerbeck

The Design and Physical Properties of An Optimized Chitosan Hydrogel for Potential Use in Endodontics , Hunter Housley

Comparison of Power Versus Manual Toothbrush in Reducing Gingivitis , Keerthi Kamreddy

Efficacy of Invisalign Attachments: A Retrospective Study , Theresa Karras

Evaluation of Corrosion Mechanisms in Stainless Steel Orthodontic Retainer Wires , Jamie Martin

Injectable Gels with Potential Use in Endodontics , Maksim Montatskiy

Effect of Different Implant Abutment Materials on Optical Properties of Translucent Monolithic Zirconia Crowns , Nisha Patel

Evaluation of Accuracy of Static Computer-Guided Implant Placement Compared with Partially-Guided or Free-Hand Placement , Laxmi Sukhtankar

The Effect of Mechanical Vibration on Alveolar Bone Following Experimental Periodontitis - A Micro-CT Study , Andrei Dan Taut

The Influence of Full Coverage Restorations On Pulp Vitality: A Ten-Year Retrospective Study , Abby Yavorek

Theses/Dissertations from 2018 2018

Effect of Different Finish Line Designs on the Marginal and Internal Fit of Metal Copings Made by Selective Laser Melting Technology , Adel Al Maaz

Effect of Emergence Profile of a Single Implant Restoration on the Health of Peri-Implant Soft Tissue , Waleed Nasir Asiri

Application of Mechanical Vibration to Enhance the Stability After Orthodontic Treatment - A Micro - CT Study , Nicolas Branshaw

A Retrospective Analysis of Patient Medical and Dental Treatment Histories, and MRONJ-Related Events , Jon Irelan

Orthodontic Bond Strength Comparison Between Two Filled Resin Sealants , James Kolstad

Comparison of Immediate vs. Delayed Recall of Orthodontic Information Following an Electronic Reminder , Michael Lenz

Orthodontic Open-Coil Spring Deactivation Forces Differ with Varying Activation Levels , Ryan Lubinsky

Factors Effecting Survival of Teeth with Nonsurgical Root Canal Therapy Including a Multi-State Outcome Analysis , Alex Moore

Orthodontic Treatment Planning Using Direct Visual Approximation of Arch Length Discrepancy and Cephalometric Analyses , Kathleen Rouse Vaught

Comparison of Different Temperatures on Bending Properties of Six Niti Endodontic File Systems , Sukbum Yoo

Theses/Dissertations from 2017 2017

QMIX 2in1 and NaOCI Precipitate: Documentation, Identification, and Exothermic Reaction , Gordon L. Barkley III

Viability of Human Periodontal Ligament Fibroblasts After Time in Tooth Storage Media , Scott MacDonald

Effects of Palatal Expansion on Speech Production , Jason Milton Meinhardt

Reliability of Digital Dental Cast Measures as Compared to Cone-Beam Computed Tomography for Analyzing the Transverse Dimension , Brian Michel

Analysis of Flexural Strength and Monotonic Load to Failure Following Simulated Chairside Adjustments and Repair in a Lithium Disilicate Glass-Ceramic , Ali Ramadhan

The Effect of Heat Treatment on the Bending Properties of a Cobalt-Chromium Orthodontic Wire , Alex Schwab

Comparison of Anterior Denture Teeth Arrangements Made with the Tooth Mold Template and Definitive Computer-Aided Design & Computer-Aided Manufacturing Complete Removable Dental Prostheses , Jose Antonio Sierra

Thermal Properties of Commonly Used Clear Aligner Systems As-Received and After Clinical Use , Louis Wenger

Direct Visual Approximation of Arch Length Discrepancy and Cephalometric Measurements , Bradley J. Wurm

Survival Rates of Primary Endodontic Therapy Following Core/Post and Crown Placement , Kandace Yee

Theses/Dissertations from 2016 2016

Evaluation of Die Trim Morphology Made by CAD/CAM Technology , Pratiksha Agrawal

Outcomes of Primary Endodontic Therapy Provided by Endodontic Specialists Compared to Other Providers , Jacob Burry

The Effect of Mechanical Vibration on Human PDL Cell Differentiation and Response to Inflammation , Megan DesRoches

Color Change of Commercial Resin Composited with Different Photoinitiators , Feng Gao

The Effects of Mechanical Vibration on Human Chondrocytes In Vitro , Bradley J. Gauthier

Thermal Properties of Copper Nickel-Titanium Orthodontic Archwires , Joshua Gilbert

Torsion and Bending Properties of EdgeEndo Files , Chad Hansen

Mitigating Distortion of Light-Polymerized Composite Trial Bases , Jon Patrick Irelan

Viability of Human Periodontal Ligament Fibroblasts After Storage in Save-A-Tooth, EMT Toothsaver and Hank's Balanced Salt Solution , Wonhee Lee

Page 1 of 8

Advanced Search

• Notify me via email or RSS
• Collections
• Disciplines

Information about e-Pubs@MU

• General FAQ
• School of Dentistry

Home | About | FAQ | My Account | Accessibility Statement

Privacy Copyright

• Areas of Research

Research Projects

Research within the School of Dental Medicine encompasses a wide variety of fields within oral health care, helping to translate basic science discoveries into clinical therapies. Use the links below to learn more about current and past projects of faculty, staff, and students. 

Search by Department

Search individual research projects and faculty areas of research interest by School of Dental Medicine Departments

Biological Sciences

Biological Sciences research focuses on how the body, particularly the mouth, fights diseases through innate immune responses. 

**We are currently updating these pages to refresh information. While we work, please visit the Biological Sciences Research and Sponsored Projects page to review our active projects.

Ge Jin, PhD

• Beta-defensins in Immunological Responses and Immunotherapy in Oncogenesis
• Innate Immunity and Oral Carcinogenesis

Pushpa Pandiyan, PhD

• Mechanism of Immunomodulation during Oropharyngeal Candidiasis
• Modulation of Tumor Necrosis-α during Oropharyngeal Candidiasis

Aaron Weinberg, DMD, PhD

• Oral Cancer and the Discovery of a Novel Biomarker
• Oral Cancer and the Discovery of a Novel Biomarker - Taiwan
• Fusobacterial-Associated Beta Defensin Inducer (FADI)
• Center for Excellence in Immunology

Fengchun Ye, PhD

• Role of Angiopoietin-2 in KSHV Induction of Angiogenesis, Inflammation, and Cutaneous KS Lesions
• Epigenetic Regulation of Viral Infection and Replication by Periodontal Bacteria

Chad Zender, MD, FACS

• Comprehensive Head and Neck Database 

Community Dentistry

Community Dentistry research focuses on the protection and improvement of oral health in patients and community at-large. 

**We are currently updating these pages to refresh information. While we work, please visit the Community Dentistry Research and Sponsored Projects page to review our active projects.

Catherine Demko

• MEDTAPP Healthcare Access Initiative
• Sisters of Charity of Canton Evaluation Project

James Lalumandier, DDS, MPH

• Geriatric Dentistry Mobile Unit Program
• Healthy Smiles Sealant Program

Sena Narendran, PhD

• Post-doctoral Training in General, Pediatric, and Public Health Dentistry and Dental Hygiene
• Pre-doctoral Training in General, Pediatric, and Public Health Dentistry and Dental Hygiene

Suchitra Nelson, PhD

• Family Intervention with Caregivers of Children with Urgent Dental Needs
• Longitudinal Studies of Dental Caries in Very Low Birthweight Children

Mary Beth Slusar, PhD

• Caregiver Illness Perception and Child's Early Childhood Caries Status

Kristin Victoroff

• Collaborative Home for Oral Health, Medical Review, and Health Promotion (CHOMP)

Kristin Williams

Comprehensive Care

• Correlation of Primary Implant Stability with Cone Beam Computed Tomography Analysis in a Bovine Mandibular Bone Model
• Image Guided New Biomaterials for Dental Restorations
• Optimization of Insertion Torque for Primary Dental Implant Stability

Endodontics

Anita Aminoshariae, DDS, MS

• Association of Endodontic Conditions with Systemic Medical Disease
• Effect of Time Factor in Crown Placement on Survival of Primary Endodontically Treated: A Retrospective Cohort Study

Thomas Montagnese, DDS

• Efficacy of Buprenorphine on Post-operative Endodontic Analgesia 

Oral and Maxillofacial Medicine + Diagnostic Sciences

Oral Medicine research focuses on orofacial pain, oral premalignant disorders, interprofessional education outcomes, and markers for response to treatment of mucosal disorders.

Andres Pinto, DMD, MPH

• Osteonecrosis of the Jaw (ONJ) Case Registry
• Reliability of a Modified Brief Pain Inventory-Facial

Oral and Maxillofacial Surgery

Dale Baur, DDS

• Patient-Centered Quality of Live (QOL) Measures after Temporomandibular Total Joint Replacement Surgery 
• Removal of Unerupted Third Molars at the Time of Mandibular Sagittal Split Osteotomy: Case Series 
• Treatment Outcomes of Keratocystic Odontogenic Tumor

Orthodontics

**We are currently updating these pages to refresh information. While we work, please visit the Orthodontics Research and Sponsored Projects page to review our active projects.

Mark Hans, DDS, MSD

• Craniofacial Initiatives in the School of Dental Medicine

J. Martin Palomo, DDS, MSD

Manish Valiathan, DDS, MSD

• Craniofacial Growth Prediction in Different Facial Types

Pediatric Dentistry

Pediatric Dentistry research focuses on improving the care and treatment of pediatric oral health, including pediatric oral health disparities, craniofacial anomalies, and oral health behavior.

*We are currently updating these pages to refresh information. While we work, please visit the Pediatric Dentistry Research and Sponsored Projects page to review our active projects.Orthodontics

Gerald Ferretti, DDS, MS, MPH

Research Interests:

• Reducing children's oral health disparities
• Craniofacial anomalies
• Pediatric sedation

Masahiro Heima, DDS, PhD

• Dental care-related fear and anxiety
• Oral health care behavior

Lance Vernon, DMD, MPH

• Oral hygiene behavior
• Oral health care in HIV population
• Development of a Provider-Observed Tool to Assess Oral Hygiene Skills in HIV+ Adults
• Holistic, Prevention-Focused Assessment and Coaching of Targeted/Tailored Oral Hygiene Behaviors
• Immune and Inflammatory Consequences of Intensive Periodontal Disease Treatment in HIV+ Adults
• Oral Link to Vascular Disease in an HIV-1 Cohort

Periodontics

Nabil Bissada

• Gingival Dimension Around Natural Teeth and Dental Implants in Health and Disease
• Role of Nonsurgical Periodontal Treatment on the Level of Rheumatoid Factor in Patients Diagnosed with Rheumatoid Arthritis

Andre Paes, DDS, PhD, MS

• Examination of Proton Pump Inhibitor Use and Colonization with Trichomonas tenax and Entamoeba gingivalis

Leena Palomo, DMD, MSD

• Analysis of Postmenopausal Women Using Bisphosphonate Therapy
• Periodontitis in Postmenopausal Women

Information

• Author Services

Initiatives

You are accessing a machine-readable page. In order to be human-readable, please install an RSS reader.

All articles published by MDPI are made immediately available worldwide under an open access license. No special permission is required to reuse all or part of the article published by MDPI, including figures and tables. For articles published under an open access Creative Common CC BY license, any part of the article may be reused without permission provided that the original article is clearly cited. For more information, please refer to https://www.mdpi.com/openaccess .

Feature papers represent the most advanced research with significant potential for high impact in the field. A Feature Paper should be a substantial original Article that involves several techniques or approaches, provides an outlook for future research directions and describes possible research applications.

Feature papers are submitted upon individual invitation or recommendation by the scientific editors and must receive positive feedback from the reviewers.

Editor’s Choice articles are based on recommendations by the scientific editors of MDPI journals from around the world. Editors select a small number of articles recently published in the journal that they believe will be particularly interesting to readers, or important in the respective research area. The aim is to provide a snapshot of some of the most exciting work published in the various research areas of the journal.

Original Submission Date Received: .

• Active Journals
• Find a Journal
• Proceedings Series
• For Authors
• For Reviewers
• For Editors
• For Librarians
• For Publishers
• For Societies
• For Conference Organizers
• Open Access Policy
• Institutional Open Access Program
• Special Issues Guidelines
• Editorial Process
• Research and Publication Ethics
• Article Processing Charges
• Testimonials
• Preprints.org
• SciProfiles
• Encyclopedia

Journal Menu

• Applied Sciences Home
• Aims & Scope
• Editorial Board
• Reviewer Board
• Topical Advisory Panel
• Instructions for Authors
• Special Issues
• Sections & Collections
• Article Processing Charge
• Indexing & Archiving
• Editor’s Choice Articles
• Most Cited & Viewed
• Journal Statistics
• Journal History
• Journal Awards
• Society Collaborations
• Conferences
• Editorial Office

Journal Browser

• arrow_forward_ios Forthcoming issue arrow_forward_ios Current issue
• Vol. 14 (2024)
• Vol. 13 (2023)
• Vol. 12 (2022)
• Vol. 11 (2021)
• Vol. 10 (2020)
• Vol. 9 (2019)
• Vol. 8 (2018)
• Vol. 7 (2017)
• Vol. 6 (2016)
• Vol. 5 (2015)
• Vol. 4 (2014)
• Vol. 3 (2013)
• Vol. 2 (2012)
• Vol. 1 (2011)

Find support for a specific problem in the support section of our website.

Please let us know what you think of our products and services.

Visit our dedicated information section to learn more about MDPI.

Latest Research and Advances in Oral Medicine and Oral Pathology

• Print Special Issue Flyer

Special Issue Editors

Special issue information, benefits of publishing in a special issue.

• Published Papers

A special issue of Applied Sciences (ISSN 2076-3417). This special issue belongs to the section " Applied Dentistry and Oral Sciences ".

Deadline for manuscript submissions: closed (29 February 2024) | Viewed by 5056

Share This Special Issue

Dear Colleagues,

In recent years, research has focused on new diagnostic and therapeutic approaches in the management of oral diseases. Oral medicine is increasingly oriented towards prevention and early diagnosis, mainly due to the continuous development of minimally invasive and personalised diagnostic techniques.

This Special Issue aims to provide an update on the latest research and advances in oral medicine that can help improve clinical decision-making and impact the quality of life of our patients.

Topics of interest include:

• Oral cancer and oral potentially malignant disorders: diagnosis and management;
• Medication-related osteonecrosis of the jaws: diagnosis and management;
• Diagnosis and management of oral diseases (benign, infectious, and autoimmune diseases);
• Management of Special Needs Patients and medically compromised patients;
• Oral diseases in patients with systemic problems;
• New technologies in oral medicine;
• Oral prevention projects that improve oral health awareness and knowledge.

All original articles, clinical studies, case reports, case series, and review articles are welcome for submission.

We encourage the presentation of interdisciplinary works and collaborative research between more countries.

Dr. Gianluca Tenore Dr. Federica Rocchetti Dr. Ahmed Mohsen Guest Editors

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website . Once you are registered, click here to go to the submission form . Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Applied Sciences is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2400 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

• oral pathology
• oral medicine
• oral surgery
• oral cancer
• biopsy and liquid biopsy
• head and neck chemotherapy and/or radiotherapy
• oral potentially malignant disorders
• orofacial pain
• osteonecrosis of the jaws
• Ease of navigation: Grouping papers by topic helps scholars navigate broad scope journals more efficiently.
• Greater discoverability: Special Issues support the reach and impact of scientific research. Articles in Special Issues are more discoverable and cited more frequently.
• Expansion of research network: Special Issues facilitate connections among authors, fostering scientific collaborations.
• External promotion: Articles in Special Issues are often promoted through the journal's social media, increasing their visibility.
• e-Book format: Special Issues with more than 10 articles can be published as dedicated e-books, ensuring wide and rapid dissemination.

Further information on MDPI's Special Issue polices can be found here .

Published Papers (2 papers)

Further Information

Mdpi initiatives, follow mdpi.

Subscribe to receive issue release notifications and newsletters from MDPI journals

• Mission, Vision and Core Values
• Diversity, Equity and Inclusion
• Strategic Plan
• Licensing Disclosures
• Office of Education
• Academic Calendars
• Courses and Curriculum
• Tuition, Fees and Financial Aid
• Policies and Procedures
• Student Affairs
• Counseling Center
• Transcript Requests
• Helpful Links
• Patient Care Information
• Make a Payment
• Patient Portal for Current Patients
• Maps and Directions
• General Dentistry
• Oral and Maxillofacial Surgery
• Oral Biology and Pathology
• Orthodontics and Pediatric Dentistry
• Division of Endodontics
• Prosthodontics and Digital Technology
• Faculty Directory
• CBase Links
• Continuing Education
• Stony Brook Medicine Email
• Faculty Resources
• Doctor of Dental Surgery
• MS/PhD in Oral Biology and Pathology
• Advanced Dental Education Program in General Practice Residency
• Advanced Dental Education Program in Dental Anesthesiology
• Advanced Dental Education Program in Endodontics
• Advanced Dental Education Program in Oral and Maxillofacial Radiology
• Advanced Dental Education Program in Orthodontics and Dentofacial Orthopedics
• Advanced Dental Education Program in Pediatric Dentistry
• Advanced Dental Education Program in Periodontics
• Advanced Dental Education Program in Prosthodontics
• Discover Dental School
• Special Needs Dental Care Fellowship
• On The Cusp magazine
• First Thursday
• Dean's Updates
• About Giving

Master's/PhD Program

Introduction

Oral Biology and Pathology is part of the School of Dental Medicine within the Health Sciences Center. The mission of the Graduate Program in Oral Biology and Pathology is to foster academic and creative research excellence in the field of biomedical science. Our programs provide advanced training in the understanding of human oral and systemic health and disease which will provide the basis for graduate students to become academic and research leaders in educational, industrial and research and development arenas. Major areas of study include microbiology, biochemistry, immunology, developmental biology and genetics, functional morphology and biomechanics, neurobiology, bioengineering, biomaterials, stem cell biology and dental public health. 

The Graduate Program in Oral Biology and Pathology includes training by faculty from most departments within the school. We are committed to the education of non-dentists as well as dentists and dental hygienists, who seek advanced research training and careers in oral health sciences — a field closely aligned with the dental and craniofacial sciences.

The  Department of Oral Biology and Pathology  offers two graduate degrees, which are granted through the  Graduate School  at Stony Brook University. The department offers a PhD in Oral Biology and Pathology and a Master of Science (MS) in Biomedical Sciences (Track in Oral Biology and Pathology). These degrees can also be obtained as part of a combined DDS/PhD program or a combined DDS/MS program. The MS in Biomedical Sciences (Track in Oral Biology and Pathology) may also be obtained as part of a combined degree program leading to an Advanced Certificate in Endodontics/MS, Advanced Certificate in Orthodontics/MS, or an Advanced Certificate in Periodontics/MS.

The main function of these advanced degree programs is to train educators and researchers to staff dental and medical schools, dental and medical research institutes, dental and medical industrial laboratories, and to provide relevant basic science training for dentists and physicians taking postdoctoral specialty training. In addition, the graduate programs offered in the Department of Oral Biology and Pathology are of particular interest to industry-based scientists seeking additional training and advanced degrees.

The course work consists of an in-depth exposure to knowledge, directly and indirectly related to oral biology and its related sciences, and is coupled with appropriate individual research, tutorial and thesis/dissertation programs.

While the department is interested in all aspects of oral biology, active programs of research presently being conducted include the following:

• development, metabolism and control of the oral microflora on the teeth and various epithelial surfaces;
• interrelationship between systemic and oral diseases;
• ultrastructure and metabolism of healthy and diseased periodontal tissues with an emphasis on remodeling and matrix metalloproteinases;
• salivary gland function in normal and diseased states/secretory mechanisms, etiology, monitoring of and therapy for oral dryness (xerostomia)
• biology of epithelial growth and differentiation; epithelial gene therapy; mechanisms of epidermal and oral carcinogenesis;
• Oral and dental stem cells
• biology of skin and mucosal grafting; wound repair;
• acquired and innate immunity; inflammation and fibrosis

Besides a commitment to basic oral and medically related science, the department is committed to technology transfer and its relation to clinical care. It is a leader in translational research and continues to develop products for the oral and medically related health market. The department has brought more than 12 million dollars in royalty income to the university. Clinical trials are carried out to assess the safety and efficacy of various products developed by the Department in conjunction with many US and foreign industrial companies. Research grants are primarily from New York State, the National Institute of Dental and Cranial Research (NIDCR), National Institute of Arthritis, Musculoskeletal and Skin Diseases (NIAMS) and industrial companies.

  Further details may be obtained from Dr. Stephen Walker, director, Graduate Program, at [email protected] .

Students with a baccalaureate degree in the biological sciences are eligible to apply for the MS in Biomedical Sciences with a track in Oral Biology, which is focused on basic and translational oral and related sciences. The MS degree offers the non-dental student the foundation for a more advanced degree or additional training to individuals such as laboratory technicians and research scientists who may benefit from increased scientific knowledge. The MS curriculum is also uniquely suited to provide Pre-med and Pre-dental students interested in acquiring advanced didactic and research training to strengthen their application to dental or medical school. The core class requirements of this program are held in conjunction with the first and second year basic science courses offered to the dental students. The MS curriculum is credit driven and can be completed in as little as one year but traditionally is completed after two years.

This program is designed to ensure that graduates will develop the skills to initiate independent research in oral biology. The dissertation research comprises a significant part of the student’s course of study, which is at the leading edge of basic and translational biomedical sciences related to craniofacial development, oral health, disease processes and clinical therapies. The main function of this program is to train oral biology educators and researchers to staff dental and medical schools, dental research institutes, dental and medical industrial laboratories, and to provide relevant basic science training for dentists and physicians taking postdoctoral specialty training. In addition, this program has been of particular interest to industrial based scientists seeking additional training and advanced degrees as demonstrated by our alumni.

Combined DDS/PhD Degree:

Revolutionary discoveries and developments in fields such as molecular biology, biotechnology, biomaterials, tissue engineering, and regeneration therapy will radically alter how oral health care providers will diagnose and treat patients. In addition, there is a critical shortage of dental school faculty across the country, a scenario that is getting worse each year. To address these and many other projected changes in the profession, there is a need to develop a significant number of clinically trained scientists and scientifically trained clinicians. The DDS/PhD program seeks to do this by integrating the DDS program with the PhD in Oral Biology and Pathology.

All applicants must fulfill all prerequisite dental school requirements for admittance to the DDS Program and apply through  AADSAS . The AADSAS application deadline is December 1st.

Applicants are also required to complete the Graduate School Application . 

The combined PhD/DDS Program is approximately seven years in length.

The DAT may be substituted for the GRE Examination.

For more specific information, please contact the program director:

Dr. Stephen Walker [email protected]

Combined DDS/MS Degree

The DDS/MS program is designed to prepare outstanding clinical scientists thoroughly versed in clinical research capable of addressing significant issues in oral health. The master's degree may add an additional year so that students graduate with both degrees in five years. The DDS/MS degree provides considerable depth to the clinical degree, including a broad understanding of modern biomedical research. Having the MS degree strengthens any subsequent application to clinical specialty programs or academic positions.

Applicants interested in the combined DDS/MS Program must first be admitted to the DDS program at Stony Brook University. Outstanding applicants will be invited to submit a second application after matriculation in the graduate school, submitted at any time during the first two years of study. For the combined DDS/MS, applicants must apply separately to both the DDS program and the MS program.

Combined MS Degree with Advanced Certificate (AC) Programs

The combined MS with an Advanced Certificate in (Endodontics, Orthodontic, or Periodontics) is available to residents in these Advanced Specialty Education Programs. Entry into the combined MS in Biomedical Sciences (Oral Biology and Pathology Track) requires a separate application to the MS program and the AC program. We encourage students to apply to the MS program prior to or during their first year in the AC programs.

Students should confer with the directors of their Advanced Certificate Program:

Hechang Huang, DDS, MS, MSD, PhD Director, Advanced Certificate Program in Orthodontics and Dentofacial Orthopedics Director, Predoctoral Orthodontics

Thomas W. Manders, DDS Director, Division of Endodontics, Department of Periodontics and Endodontics Director, Advanced Certificate Program in Endodontics

Sri Myneni, BDS, MS, PhD Director, Advanced Certificate Program in Periodontics

For admissions to all of the graduate programs offered in the Department of Oral Biology and Pathology, in addition to the minimum Graduate School requirements, the following are required:

• A bachelor's degree and grade point average of 3.3 in the sciences and 3.0 overall are required for admission into either the Master of Science in Biomedical Sciences or PhD program in Oral Biology and Pathology.
• In addition to their transcripts, applicants are required to submit three letters of recommendation and proof of satisfactory performance on the General Aptitude and Advanced parts of the Graduate Record Examination (GRE). Satisfactory performance on the Dental Admission Test (DAT) can substitute for the GRE at the discretion of the graduate program director.
• All applicants are screened by the credentials committee of the Department. Interviews and discussions are arranged with faculty members and graduate students where possible.
• Formal approval for acceptance into the program is given by the Graduate School.

To obtain applications and for more information, please access the Graduate School website

Degree Requirements:

The Graduate Program in Oral Biology and Pathology follows the guidelines, requirements and milestones set by the Graduate School . The program also has requirements that are specific to the Oral Biology and Pathology program. The program recognizes that students from different backgrounds enter our program. Therefore, while following specific guidelines, the program also has incorporated a degree of flexibility. 

PhD PROGRAM: DEGREE REQUIREMENTS AND MILESTONES

The PhD degree is on average completed between 5 – 6 years. The requirements for the PhD include both didactic and research courses. A passing grade is considered a “B” or better. There are five elements

1.  Core Courses : Each student must complete and pass the Oral Biology and Pathology systems courses (HDO 560, HDO 561, and HDO 562).

2.  Seminar : Every semester each student must participate in and pass the Oral Biology and Pathology Seminar (HDO 690). 

3.  Elective Courses : Each student must pass at least four graduate level basic science course in related disciplines within and/or outside the department. The elective courses are chosen by the student in consultation with their dissertation advisor and Graduate Program Director. These courses should expand the student’s knowledge in fields related to their dissertation research. Visit our website for the complete list of courses.

4.  Research Design and Laboratory Techniques in Biomedical Research: This course aims to introduce theoretical principles and experimental techniques used for laboratory investigation in biomedical research. Students will familiarize themselves with the instrumentation and techniques used to investigate different molecular and cell biological problems through a combination of lectures and demonstrations. Various topics will be covered such as tissue culture and isolation and characterization of DNA, RNA and proteins using various techniques. Students will be introduced to recombinant DNA technology including cloning in various non-viral and viral vectors that allow modulation of gene expression. Transgenic mice technology and Cre-lox system and gene editing technologies will be introduced. In addition, the use of mass spectrometry, microarray and DNA deep sequencing to understand biological processes will be discussed.

5. Advancement to Candidacy Exam: Students should have already formed their Dissertation Advisory Committee (DAC) prior to scheduling their Advancement to Candidacy Exam. A student may be advanced to candidacy in a doctoral program once he/she has completed all Graduate School and departmental requirements other than the dissertation or its equivalent. Students will prepare a written dissertation proposal in consultation with their Research Advisor/Co-advisor. The proposal will be in the format of a research grant application in accordance with current NIH guidelines with page limitations to not exceed 10 pages. The written proposal MUST be shared with the Dissertation Advisory Committee (DAC) at least ONE week in advance of the examination, otherwise the exam will be rescheduled. Four basic criteria will be used to assess the student performance in the exam. [1] Scientific Premise: Is the student able to put their proposal within the context of previous work in the discipline? [2] Innovation: Is the proposal new and original? [3] Significance: Does the proposed research represent a significant advancement in the discipline? [4] Study Design: Has the student chosen methods appropriate to the question? and [5] Feasibility: Can the proposed study be completed within a reasonable time limit to complete degree requirement? Upon passing the exam and completion of all required coursework with the exception of HDO 690: Seminar, which is required of all students each semester, the Graduate Program Director (GPD) will submit a request to the Graduate School for the student’s Advancement to Candidacy.

6. Dissertation : A major part of the PhD is research and the development of a dissertation  on the findings. Each student must carry out original research that culminates in a written dissertation that is presented publicly and successfully defended. Areas of research are listed above but others may also be possible.

MS PROGRAMS: DEGREE REQUIREMENTS AND MILESTONES

The MS curriculum is approximately two years in duration and provides basic and translational oral and related biological science training. The requirements for the MS degree include both didactic and research courses. There are four elements:

1.  Core Courses : Each student must complete and pass the Oral Biology and Pathology systems courses (HDO 560, HDO 561 and HDO 562).

2.  Seminar : Every semester, each student must participate in and pass the Oral Biology and Pathology seminar (HDO 690). 

3.  Elective Courses : Each student must pass at least two graduate level basic science courses in related disciplines within and/or outside the department. The elective courses are chosen by the student in consultation with their thesis advisor, Program Advisory Committee, Thesis Committee and/or GPD. These courses should expand the student’s knowledge in fields related to their thesis research. Course listings in various programs can be found at: https://www.stonybrook.edu/sb/graduatebulletin/current/index.pdf

4.  Research Design and Laboratory Techniques in Biomedical Research:  This course aims to introduce theoretical principles and experimental techniques used for laboratory investigation in biomedical research. Students will familiarize themselves with the instrumentation and techniques used to investigate different molecular and cell biological problems through a combination of lectures and demonstrations. Various topics will be covered such as tissue culture and isolation and characterization of DNA, RNA and proteins using various techniques. Students will be introduced to recombinant DNA technology including cloning in various non-viral and viral vectors that allow modulation of gene expression. Transgenic mice technology and Cre-lox system and gene editing technologies will be introduced. In addition, the use of mass spectrometry, microarray and DNA deep sequencing to understand biological processes will be discussed.

5.  Thesis Research : An original research thesis is required for completion of the MS degree. Each student must carry out research (HDO599) culminating in a written thesis, which is defended before the student’s Thesis Committee. For the M.S. degree, the student defends the thesis only to the student’s dissertation committee. If the thesis is recommended for approval, the determination is submitted to the Graduate School for final decisions to award the degree

The Combined Degree Programs: DDS/PhD PROGRAM; DDS/MS; Advanced Certificate/MS: DEGREE REQUIREMENTS AND MILESTONES

The requirements for the PhD/DDS program and the DDS/MS program are similar as those for students in the stand alone PhD program or MS program with the following exceptions: Students who obtain a passing grade in HDO 501 will not be required to take HDO 560 and students who obtain a passing grade in HDO 601 will not be required to take HDO 561 and HDO 562. These students are also exempt from the required seminar course (HDO 690). Students may also opt to use Med500b (Molecular Foundations of Medicine) as an elective in lieu of MCB 656-Cell Biology.

The requirements for the Advanced Certificate/MS are similar as those in the stand alone MS program. Because students in these programs have a DDS from a US or Canadian institution, they participate in a more advanced oral biology and pathology course consisting of: HDO 531-Normal and reparative tissue development in the oral cavity; HDO 532-Host-parasite interactions; and HDO 533-Regional anatomy, orofacial neuroscience and pain conditions. In addition, students in these programs are required to participate in multiple seminar courses in which they present the current basic science literature in their field.These students are not required to take the oral biology journal club (HDO 690).

Courses: HDO 500 Biology of the Oral Mineralized Tissues This course deals with the basic chemistry, crystallography, ultrastructure, and metabolism of the calcium phosphates involved in the formation and physiological and pathological resorption of the various mineralized tissues found in or associated with the oral cavity (enamel, dentin, cementum, bone). Ectopic calculus formation will be examined. Prerequisites: HDO 560, 561, 562 and 563 or their equivalent. Fall and Spring Prerequisite: Admission to Graduate Health Sciences Program 3 credits, Letter graded (A, A-, B+, etc.)

HDO 510 Salivary Metabolism and Secretion

Consideration is given to the normal and abnormal structure and function of the glandular systems found in the oral cavity. The composition, regulation, and functions of the secretions from the major and minor salivary glands will receive particular attention. Prerequisites: HDO 560, 561, 562 and 563 or their equivalent. Fall and Spring Prerequisite: Admission to Graduate Health Sciences Program 3 credits, Letter graded (A, A-, B+, etc.)

HDO 520 Oral Microbial Systems This course explores the oral microbiome as determined using both live culture and molecular “next generation sequencing” methodologies with a focus on changes in the oral microbiome during oral disease.  Prerequisite: HDO 560, 561 and 562 or their equivalent Prerequisite: Admission to Graduate Health Sciences Program 3 credits, Letter graded (A, A-, B+, etc.)

HDO 530 Molecular Biology and Pathology of the Periodontium This course deals with the ultrastructure and biochemical composition of the periodontal tissues, remodeling of the extracellular matrix with an emphasis on the role of metalloproteinases; the microbial interrelations with the organic and inorganic components of the periodontal tissues, the biochemical dynamics of gingival inflammation and wound healing, and the metabolic processes responsible for the composition and flow of gingival crevicular fluid. Prerequisites: HDO 560, 561 and 563 or their equivalent. Fall and Spring. Please note that this may be taken twice for a total of four credits. Prerequisite: Admission to Graduate Health Sciences Program 2 credits, Letter graded (A, A-, B+, etc.)

HDO 534 Research Design and Biostatistics This course aims to improve the understanding of basic research methods and statistical concepts and principles and introduce some fundamental statistical tools, in the context of oral health research. The first part of this course covers basic assumptions and concepts of clinical and biomedical research, research methodologies, critical thinking, and evidence-based dentistry. Residents will develop the skills needed to recognize the quality of the scientific evidence and the quality of various publications, the ability to conduct an evidence-based analysis of the literature, and the ability to present an evidence-based presentation on a controversial topic related to dentistry. The components of a research proposal and the basic elements of compliance will be discussed. The second part of the course covers concepts from statistics such as: summarizing, organizing, and presenting different types of sample data; simple probability; discrete and continuous probability distributions such as the Binomial and Normal distributions; the mean and variance of a probability distribution; sampling distributions; hypothesis testing; statistical significance; confidence intervals; non-parametric techniques; ANOVA; correlation and regression; categorical data analysis, tests for proportions, and Chi-Squared tests. Students will apply the techniques learned in class on a given data set, where they will analyze the data and perform statistical testing. The third part of the course students will discuss and evaluate the statistical methods used in relevant papers as well as in proposed student’s projects. Prerequisite: Enrollment in a graduate program in the School of Dental Medicine. Fall, 1 credit, Letter grades (S/U)

HDO 535 Epithelial Keratinization and Differentiation Epithelial Keratinization and Differentiation The course examines the growth and differentiation of startified sqamous epithelia. Particular emphasis is placed on molecular events involved in the differentiation program. Consideration is also given to mechanisms involved in oral and cutaneous disorders. Prerequisites : Permission of instructor required; HBP 531 suggested; students must have had a background in cellular biochemistry molecular biology. Fall and Spring, 2 credits, Letter graded (A, A-, B+, etc.)

HDO 540 Research Design and Laboratory Technique in Biomedical Research The first part of this course covers basic assumptions and concepts of clinical and biomedical research, research methodologies, and critical thinking. Students will develop the skills needed to recognize the quality of the scientific evidence and the quality of various publications, the ability to conduct an evidence-based analysis of the literature, and the ability to present an evidence-based presentation. The components of a research proposal and the basic elements of compliance will be discussed. The second part of the course aims to introduce theoretical principles and experimental techniques used for laboratory investigation in biomedical research. Students will familiarize themselves with the instrumentation and techniques used to investigate different molecular and cell biological problems through a combination of lectures and demonstrations. Various topics will be covered such as tissue culture and isolation and characterization of DNA, RNA and proteins using various techniques. Students will be introduced to recombinant DNA technology including cloning in various non-viral and viral vectors that allow modulation of gene expression. Transgenic mice technology and Cre-lox system and gene editing technologies will be introduced. In addition, the use of mass spectrometry, microarray and DNA deep sequencing to understand biological processes will be discussed. Prerequisite: Enrollment in the MS (HBBMS) or PhD (HDOPH) program in Oral Biology and Pathology. Fall, 3 credits, Letter graded (A, B, C, F)

HDO 541 Principles of Mucosal Immunology The mucosal immune system is essentially the primary site of interaction between invading pathogens and the immune system. The overall aim of this graduate course is to facilitate a deeper understanding of the fundamentals of the immune system at mucosal surfaces. It will provide a broad overview of several core mucosal immunology topics and has been designed for graduate students and post-docs who have recently entered the field. This class will provide in-depth analysis of the structural features that distinguish the mucosal immune system from the peripheral immune system. Features of innate and adaptive immunity as they relate to mucosal immune responses will also be covered. As well as delivering in depth lectures on relevant and emerging topics the course will engage participants in interactive discussions on topics in an informal setting. The course content is based on the "Principles of Mucosal Immunology" textbook. Prerequisite: Enrollment in the MS (HBBMS) or PhD (HDOPH) program in Oral Biology and Pathology. Fall, 3 credits, Letter graded (A, B, C, F) HDO 550 Oral Diagnostics and Therapeutic Technology, Lectures and Laboratory Techniques Recent advances in the use and development of research technology for the early diagnosis and treatment monitoring of oral and systemic disease. Special attention is paid to the principles of technology transfer including patents and patenting; searching of on-line databases is a key component. The course includes relationships of dry mouth to salivary physiology, diabetes, and drug medications; salivary film measurements, wetting of oral surfaces, viscoelasticity and lubricity; the use of the Periotron and enzyme assays for the diagnosis of gingivitis and periodontal disease; instrumentation used in sensitive teeth measurement and evaluation of treatment effectiveness using oral compositions and iontophoresis; oral candidiasis and denture stomatitis and early detection and causes of dental caries; oral malodor measurements including use of the Halimeter and its use in the formulation of oral compositions. Application to clinical practice and clinical studies is covered. Prerequisites: HDO 560, 561, 562, and 563 or their equivalent. Fall and Spring Prerequisite: Admission to Graduate Health Sciences Program 3 credits, Letter graded (A, A-, B+, etc.) HDO 560 Oral Biology and Pathology I The first of four comprehensive courses on molecular structure, biochemical and physiological function, developmental anatomy and pathology of the various systems that constitute the oral apparatus. Covers the embryological development of the face and oral cavity and the biology and pathology of the oral mineralized tissues. Prerequisites: Undergraduate degree in basic science. Fall and Spring Prerequisite: Admission to Graduate Health Sciences Program 3 credits, Letter graded (A, A-, B+, etc.) HDO 561 Oral Biology and Pathology II The second of four comprehensive courses on molecular structure, biochemical and physiological function, developmental anatomy and pathology of the various systems that constitute the oral apparatus. Covers the biology and pathology of the periodontal structures and the microbiology of the oral cavity. Prerequisites: Undergraduate degree in basic science. Fall and Spring Prerequisite: Admission to Graduate Health Sciences Program 3 credits, Letter graded (A, A-, B+, etc.) HDO 562 Oral Biology and Pathology III This course is the third of four comprehensive courses on molecular structure, biochemical and physiological function, developmental anatomy, and pathology of the various systems that constitute the oral apparatus. The course consists of' the following two units of instruction; (1) the biology and pathology of the salivary glands and their products and (2) the biology and pathology of the periodontal structures, Prerequisites: Undergraduate degree in basic science. Fall and Spring Prerequisite: Admission to Graduate Health Sciences Program 3 credits, Letter graded (A, A-, B+, etc.)

HDO 563 Oral Biology and Pathology IV This course is the last of four comprehensive courses on molecular structure, biochemical and physiological function, developmental anatomy and pathology of the various systems that constitute the oral apparatus. Covers the biology and pathology of the oral sensory systems and the biology and pathology of oral motor systems. Prerequisites: Undergraduate degree in basic. Fall and Spring Prerequisite: Admission to Graduate Health Sciences Program 3 credits, Letter graded (A, A-, B+, etc.) HDO 590 Research Projects in Oral Biology and Pathology Individual laboratory projects closely supervised by faculty members to be carried out in their research laboratories. Prerequisite: Enrollment in a MS or PhD program in Oral Biology and Pathology. Fall and Spring Prerequisite: Admission to Graduate Health Sciences Program 3 credits, Letter graded (A, A-, B+, etc.)

HDO 599 Graduate Research Original investigations undertaken with supervision of a faculty member. Prerequisite: Enrollment in a MS or PhD program in Oral Biology and Pathology. Fall and Spring Prerequisite: Admission to Graduate Health Sciences Program 1-12 credits, Letter graded (A, A-, B+, etc.) HDO 690 Oral Biology and Pathology Seminars Research seminars by students, staff, and visiting scientists which may include review of current literature and presentation of student research. Prerequisite: Enrollment in the MS or PhD program in Oral Biology and Pathology.  Fall and Spring, 1 credit, Letter graded (S/U). May be repeated for credit.

HDO 695 Oral Biology and Pathology Teaching Practicum Practice instruction in the teaching of oral biology and pathology at the undergraduate level carried out under faculty orientation and supervision. Prerequisite: Permission of instructor required. Fall and Spring Prerequisite: Admission to Graduate Health Sciences Program 1 credits, Letter graded (A, A-, B+, etc.)

HDO 699 Dissertation Research in Oral Biology and Pathology Dissertation Research, Prerequisite: Advancement to Candidacy Passing, Fall, Spring, and Summer. Prerequisite: Admission to Graduate Health Sciences Program 1-9 credits, Letter graded (A, A-, B+, etc.)

HDO 805 Summer Research In Oral Biology and Pathology Summer Research, Prerequisite: Enrollment in a MS or PhD program in Oral Biology and Pathology. Prerequisite: Admission to Graduate Health Sciences Program 0 credits, S/U grading

Facilities:

The Department currently occupies 18,000 square feet of space in Dutchess and Westchester Halls comprised of offices, research laboratories, special facilities and rooms with special equipment. These include:

• extensive tissue culture facilities especially for growth of keratinocytes, fibroblasts and other cell types.

• isotope counters
• preparative ultra and analytical centrifuges
• atomic absorption; amino acid analyzer
• gas and high-pressure liquid chromatography systems
• high-voltage, and polyacrylamide gel electrophoresis systems
• fluorescence densitometer and microdensitometer ; ultraviolet/visible spectrophotometers
• fluorescence microscopes and other microscopes of various types
• automated micro-hardness tester
• specialized anaerobic bacteriology facility; automated colony counters
• electronic, mechanical and wood shop facilities

In addition, Stony Brook University Supports a number of Research Core Facilities, which are coordinated under the Office of Scientific Affairs . The goal of these facilities is to provide commonly used technologies to the campus, and thus facilitate the research processes.

The university libraries maintain 1.7 million bound volumes and 3 million publications in microformat, and subscribe to approximately 13,300 periodicals and serial titles. Excellent collections are available in the biology and chemistry libraries. The Health Sciences Library contains more than 250,000 volumes and subscribes to 4,300 periodical and serial titles. Almost all of the dental research journals are included in this collection.

Graduate Program Faculty Members   Dr. Soosan Ghazizadeh , Oral Biology and Pathology Dr. Lorne Golub , Oral Biology and Pathology Dr. Raveena Jagwani , Oral Biology and Pathology  Dr. Steven London , Oral Biology and Pathology Dr. Marcia Simon,  Oral Biology and Pathology Dr. Stephen Walker,  Oral Biology and Pathology Dr. Richard Faber, Orthodontics and Pediatric Dentistry Dr. Zach Faber, Orthodontics and Pediatric Dentistry Dr. Hechang Huang, Orthodontics and Pediatric Dentistry Dr. Robert Lopatkin, Orthodontics and Pediatric Dentistry Dr. Robert Schindel, Orthodontics and Pediatric Dentistry Dr. Vincent Iacono , Periodontology Dr. Srinivas Myneni , Periodontology Dr. Georgios Romanos , Periodontology Dr. Marcus Abboud, Prosthodontics and Digital Technology Dr. Dan Colosi,  Prosthodontics and Digital Technology Dr. Rafael Delgado-Ruiz , Prosthodontics and Digital Technology Dr. Mina Mahdian , Prosthodontics and Digital Technology Dr. Jerome Cymerman , Endodontics Dr. Clarissa Amarillas , General Dentistry Dr. Ana C. Botta , General Dentistry Dr. Ying Gu , General Dentistry Dr. Miriam Rafailovich , Materials Science and Engineering Dr. Chad Korach, Mechanical Engineering

American Dental Education Association American Dental Association International/American Association of Dental Research National Institute of Dental and Craniofacial Research (NIDCR)  

An official website of the United States government

The .gov means it’s official. Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

The site is secure. The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

• Publications
• Account settings

Preview improvements coming to the PMC website in October 2024. Learn More or Try it out now .

• Advanced Search
• Journal List
• v.15(9); 2023 Sep
• PMC10591112

A Literature Review of the Future of Oral Medicine and Radiology, Oral Pathology, and Oral Surgery in the Hands of Technology

Ishita singhal.

1 Oral Pathology and Microbiology and Forensic Odontology, Shree Guru Gobind Singh Tricentenary (SGT) University, Gurugram, IND

Geetpriya Kaur

2 Oral Pathology and Microbiology, Paradise Diagnostics, New Delhi, IND

3 Dentistry, Dierick Dental Care, Antwerp, BEL

Aparna Pathak

4 Oral Pathology, Paradise Diagnostics, New Delhi, IND

In the realm of dentistry, a myriad of technological advancements, including teledentistry, virtual reality (VR), artificial intelligence (AI), and three-dimensional printing, have been extensively embraced and rigorously evaluated, consistently demonstrating their remarkable effectiveness. These innovations have ushered in a transformative era in dentistry, impacting every facet of the field. They encompass activities ranging from the diagnosis and exploration of oral health conditions to the formulation of treatment plans, execution of surgical procedures, fabrication of prosthetics, and even assistance in patient distraction, prognosis, and disease prevention. Despite the significant strides already taken, the relentless pursuit of new horizons fueled by human curiosity remains unabated. The future landscape of dentistry holds the promise of sweeping changes, notably characterized by enhanced accessibility to dental care and reduced treatment durations. In this comprehensive review article, we delve into the pivotal roles played by AI, VR, augmented reality, mixed reality, and extended reality within the realm of dentistry, with a particular emphasis on their applications in oral medicine, oral radiology, oral surgery, and oral pathology. These technologies represent just a fraction of the technological arsenal currently harnessed in the field of dentistry. A thorough comprehension of their advantages and limitations is imperative for informed decision-making in their utilization.

Introduction and background

The world has witnessed remarkable evolution across numerous domains, with technology standing as a pivotal driver of this transformation. In the realm of healthcare, technology has ushered in a wave of innovations that encompass artificial intelligence (AI), virtual reality (VR), augmented reality (AR), mixed reality (MR), extended reality (XR), and robotic applications, all aimed at enhancing patient care. While concerns about technology encroaching on human roles in healthcare persist, there is a prevailing belief that these advancements can empower healthcare professionals to deliver superior patient care. This empowerment comes in the form of augmented decision-making capabilities, improved long-term patient tracking, expedited image analysis, and exceptional predictive capabilities. Notably, AI and machine learning (ML) are seen as complementary tools that enhance human expertise rather than replace it. As with any innovation, these technologies come with their own set of advantages and challenges. In this comprehensive review article, we delve into the multifaceted roles of AI, VR, AR, MR, and XR within the field of dentistry. Our focus will be on their applications in oral medicine, oral radiology, oral surgery, and oral pathology, providing insights into how these technologies are reshaping and optimizing dental practice for both professionals and patients.

AI encompasses the theory and development of computer systems capable of performing tasks typically associated with human intelligence, such as visual perception, speech recognition, decision-making, and language translation [ 1 ]. In the realm of healthcare, AI finds practical applications in advanced online search engines, recommendation systems, and creative tools [ 2 ]. One subset of AI, known as ML, focuses on the development of computer algorithms and models that enable systems to learn from and make predictions or decisions based on data, without being explicitly programmed to perform specific tasks. In essence, ML allows computers to recognize patterns, make sense of data, and improve their performance or behavior over time through experience [ 3 ]. In the context of dentistry, AI has been harnessed to automatically analyze dental X-rays, yielding crucial insights such as X-ray type, potential tooth impact, precise degree of bone loss through color overlays, cavity location, and more [ 4 ]. Deep learning (DL), a specialized branch of ML characterized by multi-layered computational networks, has emerged as a game-changer, particularly in medical and dental image processing [ 5 , 6 ]. The promise of ML and DL in dentistry extends to enhanced diagnostic accuracy and treatment planning. For instance, a noteworthy development at the University of California involved the creation of an AI algorithm with a remarkable 94% accuracy rate in detecting periodontitis. This algorithm exhibited diagnostic accuracies of 73% for distinguishing normal from diseased cases and 59% for classifying the severity levels of bone loss. Further optimization of the periodontal dataset holds the potential to transform this computer-aided detection system into an efficient tool for periodontal disease detection and staging [ 7 ]. In addition to periodontitis, DL algorithms have also proven adept at accurately identifying dental caries in X-rays. These technologies, characterized by their objectivity and reduced bias, hold the promise of revolutionizing dentistry by standardizing and improving the diagnostic process [ 6 ].

VR is a computer-generated simulation of a hypothetical, immersive, three-dimensional (3D) world or picture that may be interacted with using certain technologies [ 8 ]. VR has been utilized in medicine to great effect as a distraction tool during operations as well as an acclimatization technique to prepare for an experience or procedure, as stated in systematic reviews and randomized control experiments [ 9 ]. Although it has not yet gained widespread acceptance in dentistry, it may potentially play a part in exposure-based acclimation to dental events. In comparison to no intervention, three trials employing VR in a dental context found reduced pain and anxiety. The perioperative phase served as the setting for all three of these studies [ 9 ]. VR may be employed to eradicate dental phobia in pediatric and geriatric patients and further enhance patient education. Before performing procedures on actual patients, dentists, and dental students can practice and test them on mannequins using VR technology by utilizing 3D models of teeth or a human head. Additionally, VR may be used to teach new dentists and make sure seasoned dentists maintain their skill sets [ 10 ].

AR is a technique that superimposes digital data over the physical environment. Incorporating computer-generated sensory input like audio, video, graphics, or GPS data improves the user's impression of reality [ 11 ]. By immediately displaying healthcare data on the patient and merging the physical and digital worlds, AR primarily seeks to improve clinical practice. By adopting interactive approaches, AR and VR technology can help dentists explain various dental operations to their patients, establish a diagnosis, create a treatment plan, and clearly illustrate predicted results by using 3D models of their patient's teeth, gums, and oral cavities [ 12 ].

VR and AR are both combined in MR. It makes it feasible to embed features in a real setting by enabling digital things to interact with the physical world. MR equipment can be utilized in dentistry for surgical planning and training. It could offer a fresh idea for people getting dental treatment when it comes to giving consent. The Microsoft HoloLens is an MR device that can display information and potentially create a virtual environment utilizing a real-time, 3D platform employing several sensors and holographic processing. The HoloLens technology may be utilized as an essential tool for dentistry education and surgery planning, given how quickly technology is developing and how popular virtual learning is becoming [ 13 , 14 ].

XR is an umbrella term that encompasses all types of technologies that enhance our senses, including VR, AR, and MR [ 15 ]. Additionally, these technologies have been applied in several industries, including entertainment, education, and health care. It is a notion that covers both tangible and fictitious hybrid worlds, as well as human-machine interactions produced through wearables and computer technologies. Implantology and orthognathic procedures are the two dental uses of XR that occur most frequently. The development of reality gadgets makes it possible for users to mix and include both medical data and graphical information. Dental implant virtual planning, which transposes 3D virtual planning into the surgical field, has increased the precision of dental implants being inserted using either static guiding or dynamic navigation. Dental static-guided devices may not offer as many benefits in dental implantology as computer-assisted surgery with dynamic navigation. These kinds of technologies overlay computed cone-beam tomography (CBCT) depth, angle, and drill position on the pictures, assisting dentists in performing minimally invasive procedures and avoiding damage to important structures. Because computer-aided navigation increases treatment precision while lowering operational hazards, the adoption of such technology is also beneficial in oral and maxillofacial surgery. Users may occasionally wear a head-mounted display or a glove that stimulates their visual, auditory, and tactile senses, as well as their sense of touch, to create an immersive virtual experience.

Currently, mock-ups, video analysis, and 3D face conceptions have all been employed to help with the technique of reconstructing smiles during dental rehabilitation. The development of new technology improves this program and cuts down on the amount of time and chance of mistakes involved in knowledge exchange between patients, physicians, and laboratories. Increased realism grin programs locate the smile in the photograph and replace it with a different smile for the greatest fit [ 15 ].

Technology has indeed revolutionized the field of dentistry, making it more comfortable, efficient, and effective for patients. Other technical developments that have influenced modern dentistry include laser dentistry, CAD/CAM, 3D printing, and regenerative dentistry. In addition to these developments in dentistry, these technologies are also having a big impact on how dental care is provided.

In the current decade, we are gradually entering the realm of the fourth dimension, where experiences previously unattainable in the physical world become accessible. The history of AI can be traced back to 1956, while the origins of VR reach back to 1960 [ 16 ]. Notably, in 1962, Morton Heiling pioneered the Sensorama technology, a multisensory stimulator that incorporated color and stereo-prerecorded films, augmented by binaural scents, sound, wind, and vibration backgrounds. However, Sensorama's interactivity was limited [ 17 ]. In 1965, Ivan Sutherland demonstrated "The Ultimate Display" technology, based on the concept of constructing an artificial world that integrated interactive graphics, force feedback, olfactory, gustatory, and auditory elements [ 18 ]. Furthermore, in 1968, Sutherland introduced the first head-mounted display (HMD) system with a three-dimensional head-tracking method, aptly named "The Sword of Damocles" [ 19 ]. The year 1971 marked the development of GROPE, the first prototype of a force-feedback system at the University of North Carolina (UNC). GROPE combined haptic display and visual models [ 16 ]. In 1975, Myron Krueger established an artificial reality laboratory known as the Videoplace, creating a "conceptual environment that did not exist." This system displayed user silhouettes captured by cameras on a large screen, enabling user interaction [ 20 ]. In 1982, Thomas Furness pioneered the Visually Coupled Airborne System Simulator (VCASS), an advanced flight simulator demonstrated at the US Air Force’s Armstrong Medical Research Laboratories. Fighter pilots utilized an HMD that integrated the outside view with graphics displaying precise flight path information [ 16 ]. In 1984, NASA Ames developed the Virtual Visual Environment Display (VIVED), featuring a stereoscopic monochrome HMD [ 21 ]. The VPL company made significant strides in commercial VR technology, introducing the iconic Data Glove technology in 1985 and the marketable Eyephone HMD in 1988 [ 16 ]. In 1989, Fake Space Labs introduced the BOOM technology, a compact device composed of two CRT monitors viewable through eye holes [ 16 ]. The latter part of the 1980s witnessed the creation of numerous VR devices, including optical trackers, HMDs, and the Pixel-Plane graphics engine at UNC. The architectural walkthrough was a notable application of these technologies. In 1992, the CAVE Automatic Virtual Environment emerged, amalgamating VR and scientific visualization systems. Users wore LCD shutter glasses, and stereoscopic images were projected onto the room's walls, offering high-resolution images and a wider field of view compared to HMDs [ 21 ]. In 1994, Milgram and Kishino introduced the concept of the VR continuum, encompassing five systems: AI, AR, VR, MR, and XR (Figure ​ (Figure1) 1 ) [ 16 ]. AR technology, within this continuum, enhances rather than replaces the real world. AR employs see-through HMDs to overlay virtual three-dimensional objects onto the real environment. AR holds substantial potential for enhancing human perception and facilitating complex tasks, making it a focal point of various research endeavors [ 22 ].

Image Credits: Geetpriya Kaur

Oral medicine

Virtual Reality and Augmented Reality in Oral Medicine

Conventionally, oral cavity examinations and clinical diagnostic investigations of oral lesions were either explained orally or with visual presentations. The oral medicine residents are expected to take a proper clinical history of the patient with a thorough oral cavity examination. A case history can be described as a planned professional conversation that enables the patient to communicate his or her symptoms and past personal, dental, and medical histories [ 23 ]. A 3D-augmented clinical history format can be created to record the chief complaint, medical and dental histories, as well as previous investigations. Hence, utilizing this platform will greatly help in making a provisional diagnosis of the patient and explaining the patient with the help of images.

The most common types of oral lesions encountered by an oral medicine resident are red and white lesions, vesiculobullous lesions, and ulcerative lesions. The conventional chairside diagnostic techniques include vital staining, exfoliative cytology, and optical imaging. A demonstration of these methods can be explained through a 3D-augmented platform. Haptic-based VR training stimulators can be used by oral medicine residents for the practice of these traditional techniques. Additionally, VR can also assist the dentist in ruling out false-positive and false-negative results of several vital staining procedures, including toluidine blue, methylene blue, and Lugol’s iodine.

Some oral lesions are treated with medication, while other oral lesions are recommended for biopsy. An oral premalignant condition such as oral submucous fibrosis is generally treated with hyaluronidase injections. The placement of injections and dosage can be demonstrated with the help of VR training stimulators. In the case of white lesions, the application of medications or oral intake of medicines can be explained with stimulators [ 23 ].

Incisional and punch biopsy techniques are generally preferred to evaluate potentially malignant oral disorders and oral squamous cell carcinoma. Excisional biopsy procedures are performed in cases of exophytic growth, pyogenic granuloma, and mucocele. The AR stimulators can be used for explaining and practicing biopsy procedures to oral medicine residents. Moreover, the tactile feedback mechanisms can be deeply studied to enhance biopsy procedures (Figure ​ (Figure2 2 ).

Image Credits: Geetpriya Kaur and Ishita Singhal

Artificial Intelligence in Oral Medicine

AI is nowadays a popular diagnostic modality that is being used for precise image analysis by making use of various body systems. The various AI techniques that are currently being utilized are artificial neural networks (ANNs) and genetic algorithms. In the recent decade, ANNs have been used to elucidate the findings of various investigative modalities like USG, dental radiographs, CBCT, computed tomography (CT) scans, and magnetic resonance imaging (MRI). Moreover, by using ANNs, we can manage precise generalization of settings by optimizing the goodness of fit between the input data (text or image fed into the algorithm) and output data (working classification). Additionally, ML algorithms can also provide accurate clinical findings by analyzing hospital medical records that have been hand-labeled [ 24 ].

Additionally, AI can be used as an adjunct for diagnosing oral lesions as well as planning efficacious treatment based on clinical findings. For example, AI algorithms can help in the classification of various suspicious lesions that might be undergoing malignant changes. Thus, in future research, AI can also be judiciously used for screening larger populations for genetic predisposition to oral cancer. Moreover, AI can also provide supportive diagnostic acumen along with other chief diagnostic techniques like CT, MRI, and CBCT to determine certain deviations from the normal anatomical arrangement that might have been missed by the human eye [ 24 ].

Oral radiology

Oral radiology is a specialized field of dentistry that employs various imaging methods to diagnose and treat oral diseases. Its primary role is to identify pathologies such as cysts, tumors, and infections in the oral cavity. In oral radiology, a range of imaging techniques are utilized, including radiographs, CBCT, CT scans, MRI, positron emission tomography (PET) scans, and ultrasound (USG). Radiographs are commonly employed for the detection of dental caries, periodontal disease, cysts, benign and malignant tumors, and other dental abnormalities. CT scans are particularly useful in assessing bone loss, fractures, and tumors, while MRI is effective in detecting soft tissue abnormalities such as cysts and tumors. Ultrasound is primarily utilized to evaluate salivary gland irregularities. This branch of dentistry plays a critical role in effectively diagnosing and treating oral ailments [ 25 ].

Artificial Intelligence in Oral Radiology

In the field of oral and maxillofacial radiology, AI applications hold considerable promise. CNNs, which can perform image categorization, detection, segmentation, registration, creation, and refinement, have been primarily employed in recent research on AI in oral and maxillofacial radiology. In this area, AI algorithms have been created for image analysis, forensic dentistry, radiographic diagnostics, and picture quality enhancement. Dental radiology is steadily integrating AI, with a focus on diagnostic records in CBCT and digital 3D images. To develop AI for quick diagnosis and improved treatment planning, a lot of data may be gathered and calculated. To get good results, a ton of data is required, and oral radiologists must be involved in this labor-intensive process of creating accurate and consistent data sets. There are several issues that need to be resolved before AI is extensively used in current clinical practice, including the need to build up enormous amounts of finely labeled open data sets, comprehend AI's judgment standards, and identify potential AI-based threats to DICOM. AI will advance further in the future and is anticipated to play a significant role in the creation of automatic diagnosis systems, the establishment of treatment plans, and the manufacture of treatment instruments if answers to these issues are offered with the growth of AI. As specialists who are well-versed in the properties of radiographic pictures, oral radiologists will be especially crucial in the development of AI applications in this area (Figure ​ (Figure3) 3 ) [ 25 ].

Image Credits: Dirk Neefs, DD-Care, Belgium

Virtual Reality and Augmented Reality in Oral Radiology

The use of virtual and augmented reality technology is a cutting-edge method of communication that has the potential to enhance radiology education, improve communication with coworkers, refer physicians and patients, and support interventional radiology operations. Currently, AR and VR technologies only allow the user to view content; they do not allow them to interact with the environment or receive tactile input from it. New technologies enable interaction and manipulation of the environment by people. Anatomical holograms may be "tagged" to manipulable actual items using low-cost, commercially accessible equipment like the MERGE Cube (Merge VR, San Antonio, Texas). Although VR and AR have a lot of potential for radiography, they currently have certain drawbacks, such as ergonomic issues from extended usage, relatively high adoption and use costs, and a lack of content. For instance, it has been noted that continuous usage of HMDs might result in neck discomfort, nausea, and disorientation from prolonged delay (Figure ​ (Figure4) 4 ) [ 26 ].

Oral surgery

Virtual Reality, Augmented Reality, and Mixed Reality in Oral Surgery

An oral and maxillofacial surgeon should have precise knowledge of anatomical structures and their normal physiological movements [ 27 ]. For better surgical results, AR-VR technology can provide visual access and detailed knowledge of important anatomical structures, muscles, and joint movements of the oral cavity to oral surgery residents. Based on clinical and radiological investigations, VR devices can be used to plan customized patient treatment. The Holomedicine® Association is a global network of individual experts from medicine, science, technology, and policy. They work to build new methods for delivering mixed reality technologies in medicine and surgery, ensuring they have maximum clinical impact.

Oral surgeons can be taught the administration of dental anesthesia with the help of the AR-VR platform. The main reasons for anesthesia failures are anatomical, pathological, physiological, or inappropriate techniques [ 28 ]. Additionally, anatomical and inappropriate insertion techniques can be further improved by imparting a deep knowledge of intraoral and extraoral anatomies [ 27 ]. This technology, if integrated with a feedback mechanism, can be greatly beneficial in handling larger groups of patients in a short period. A study determined the dentist feedback of haptic-based VR anesthesia injection training stimulators on two different virtual models. Although the results were satisfactory, the enhancement of tactile feedback was the main concern [ 28 ]. Another study compared inferior alveolar nerve block (IANB) teaching methods in an AR stimulator-based experimental group and a conventional technique-based control group. However, the researchers did not discuss the limitations of the feedback system [ 29 ].

In the recent decade, AR techniques have been used to assist in several oral and maxillofacial surgeries, such as orthognathic surgery, osteotomies, prosthetic surgeries, cancer surgery, temporomandibular joint analysis, excisional biopsy procedures, and dental implants [ 30 ]. An image-guided surgery system was developed using AR technology. A computer-assisted system consisted of a gadget that could monitor the instrument, whose position and direction were depicted in virtual space using a picture registration process [ 31 ]. Computer design methods were used to connect the instrument to the surgical field. Generally, oral surgeons use a pointer to connect preoperative patient images and the surgical treatment plan. Moreover, AR-based technology was developed to project pictures directly onto the surgical site. This technique uses mononuclear projection in the working microscope and head-up displays. The projections were further built on the semi-clear screens and placed between the working screen and the oral surgeon, or they were constructed on the binocular optics of a following surgical microscope [ 32 ].

In the latest study, oral surgeons used HMD to understand the superimposition of bone segments or soft tissues. This technique helped to accomplish a smoother surgical performance [ 33 ]. In another study, Oculus Rift and Leap Motion equipment were used by residents to interact with the equipment and understand its operations [ 34 ]. The Leap Motion system integrates a multi-sensory learning experience by using a particular application and zooming in on some treatment techniques within possible oral surgical procedures. This VR technology incorporated a 360-degree operating room, spherical videos, and computer-generated three-dimensional operating room models [ 27 ]. Still, further studies are required to understand the haptic force feedback and its association with the three-dimensional instrument models.

Some researchers utilized the VR platform to perform virtually simulated orthognathic surgeries and later carried out these surgical interventions on patients. The major benefit of this technology was that oral surgeons could predict patients’ aesthetic and surgical progress [ 35 ]. The AR framework was used for tracing points, lines, and planes that could be moved from the stereolithographic skull model on the facial skeleton during osteotomy and splint procedures [ 31 ]. The VR devices were also used to study the placement of dental implants. Proper surgical navigation can be used by dental surgeons to place the implants at specific locations with sufficient bone thickness, thereby preventing implant failure [ 18 ]. Thus, VR technology has been judiciously incorporated to provide proper treatment planning and determine a precise location [ 36 ].

Siepel et al. examined the application of a low-cost stereoscopic display system and six degrees of freedom in implant placement and compared it with the three degrees of freedom in the virtual world. During the follow-up research, the treatment planning was enhanced so that the dentist was provided with six degrees of freedom using CT images at the voxel level in real time [ 37 ]. The latest studies demonstrated VR systems that integrated CT images of the jawbone along with haptic force feedback technology to train beginners by simulating the sounds and vibrations of bone drilling and contra-angled handpieces [ 38 , 39 ]. In oncology cases, the oral and maxillofacial consultant can use VR technology to physically draw the tumor borders with the help of programming apparatuses onto the processed tomographic informational index (Figure ​ (Figure5) 5 ) [ 40 ].

Image Credits: Yujia Gao (NUHS, Singapore) provided their original images for publication. 

Artificial Intelligence in Oral Surgery

In many recent studies, machine learning algorithms have been utilized for faster and more reproducible interpretation of several bone and skin landmarks that are necessary for a complete 3D analysis of facial structures. Thus, this technique has more potential than other computational techniques [ 41 ].

For managing orofacial deformities, the choice of surgery is important, along with the expertise of the orthodontist and the surgeon. Hence, training algorithms on cephalometric values as well as interpreted images can help in providing treatment support tools that can easily predict the requirement for surgical interventions during orthodontic treatment. Moreover, these AI-based tools can lend a helping hand to the assisting practitioner to either verify or revise his treatment plans accordingly to minimize orthodontic camouflage with adverse aesthetic and functional results [ 41 ].

The extraction of impacted third molars is a routine procedure performed by oral surgeons and general dentists. The use of AI-based tools can help optimize the various stages of diagnosis and treatment planning. Moreover, taking the support of a predictive AI-based model based on the eruption potential of the third molars by means of mechanized calculations of their angulation on panoramic radiographs can judiciously help in making crucial decisions pertaining to tooth extraction, which might turn out to be debatable in a few cases [ 40 , 41 ].

Oral pathology

Artificial Intelligence, Virtual Reality, and Augmented Reality in Oral Pathology

An oral pathologist evaluates the relevant stained tissue slides under a microscope and provides the patient with a histopathology report. The final diagnosis of oral lesions greatly depends on accurate clinical and radiological patient details. Furthermore, oral surgeons can further provide the required treatment to patients based on their histopathology reports.

In recent decades, light microscopy has been replaced by digital scanning techniques. However, hematoxylin and eosin (H&E) staining is still used as the standard method. It is predicted that an oral pathologist will soon be able to directly examine the oral tissues without any tissue processing steps. Thus, 3D AR or MR technology could be precisely applied in this research area for better patient outcomes. In the future, the oral tissues could be directly viewed in the patient’s mouth by utilizing in vivo microscopy to ultimately connect relevant cellular features to matching radiological images [ 42 ].

To date, microscopic morphology is regarded as the gold standard for diagnosis [ 43 ]. Worldwide, researchers are working on AI-based image analysis for the diagnosis of several oral lesions. Hence, this technology can assist an oral pathologist in making fast decisions regarding patient's histopathology reports and further investigative examinations. AI was introduced in the oral pathology domain to overcome the variability of morphologic diagnosis and to provide consistent and reliable diagnostic reports [ 44 ].

Recent research has demonstrated the role of ML in identifying, classifying, diagnosing, and differentiating different oral lesions [ 45 ]. A recent study employed CNN for the detection of keratin pearls. The researchers suggested a two-stage method for computing oral histology images. The first stage involved a 12-layered deep CNN for the segmentation of constituent layers. The keratin pearls were diagnosed in the second stage with the help of texture-based feature-trained random forests. The keratin pearls were diagnosed with 96.88% accuracy [ 46 ]. Farahani et al. examined the utilization of the Oculus Rift device for the evaluation of digital pathology slides. In their study, all three reviewers established that digital pathology slides were viewed on a VR platform with the Oculus Rift DK2 [ 47 ].

Datasets used in AI and oral cancer research are clinical photographic images, patient’s geographic data and habit history, H&E-stained histopathological images, immunostained images, saliva metabolite data, and gene expression data [ 48 ]. The limitation of the AI approach is its two-dimensional format. However, the main advantage of the AI approach in image diagnosis is that it overcomes the inconsistency of inter- and intra-observer variability [ 49 ].

The oral pathologist can be taught laboratory techniques such as tissue processing, H&E staining, and special staining techniques with the VR training stimulators. Additionally, the common diagnostic techniques at the microscopic level, such as immunohistochemistry (IHC), fine needle aspiration cytology, and fluorescence in situ hybridization (FISH), can also be duly explained with VR stimulators. The mixed reality systems can also be incorporated into dental schools to explain detailed and labeled histopathological features as well as images of various oral diseases. Moreover, the AR technology can also be used for teaching cytology slides of oral potentially malignant disorders and oral cancer cases to undergraduate and postgraduate students (Figure ​ (Figure6 6 ).

Image Credits: Ishita Singhal and Geetpriya Kaur

Advantages and drawbacks of AI, VR, AR, and MR in oral diagnostics

In the context of a growing global population and the resulting surge in healthcare demands, digital technologies have emerged as indispensable resources for managing the impending influx of patients. Notably, VR and AR platforms offer several advantages across various diagnostic fields. Their applications carry significant potential, particularly in the education of undergraduate and postgraduate students, through the implementation of interactive learning methodologies with clear, objective evaluation criteria. Furthermore, the integration of AI and automation can assume a critical role in safeguarding our healthcare workforce, especially in light of the sacrifices made by many during the COVID-19 crisis.

VR, in particular, holds promise in delivering training to healthcare professionals, covering a spectrum of procedures, from laparoscopic surgery to the evaluation of medical databases. It also plays a pivotal role in formulating treatment strategies and facilitating the rehabilitation of patients dealing with conditions such as autism, cancer, and psychiatric disorders. Moreover, these technologies facilitate advanced learning opportunities for remote students who may lack the means to travel to different cities for specialized studies. They enable the creation of interactive and engaging clinical modules, particularly beneficial in the context of ruling out differential diagnoses in complex medical cases.

However, it is essential to acknowledge that these novel technologies do come with certain limitations when applied in clinical settings. Independent research teams focusing on VR and AR may face challenges when relying on customized augmented systems in intricate experimental models, limiting their widespread applicability. While these technologies can find utility in simpler experimental models, their comprehensive integration into complex scenarios remains a subject of ongoing exploration.

Furthermore, it is worth noting that the current body of research predominantly emphasizes technical skills, particularly in the realm of dentistry, where virtual oral surgery stimulators offer some degree of skill development. Nevertheless, a critical gap exists when it comes to addressing non-technical skills, such as cognitive development, teamwork, interpersonal communication, and emergency management, which are equally vital in clinical practice. To fully harness the potential of VR and AR in health care and dentistry, there is a pressing need for additional research efforts to validate their efficacy and enhance the overall quality of treatment and healthcare delivery through augmented techniques.

Conclusions

Technological advancements in AI, VR, AR, MR, and XR have revolutionized dentistry, ushering in an era of precision, enhanced patient care, and improved education. These innovations are not here to replace human jobs but rather serve as vital tools in delivering more efficient and cost-effective patient care. These technologies have already transformed various aspects of oral health care, from diagnostics and treatment planning to surgeries and patient experiences, with the potential to eliminate traditional tools like drills and injections. In oral medicine, VR and AR enable 3D-augmented clinical histories, aid in provisional diagnoses, and enhance treatment plan explanations, while haptic-based VR training enhances diagnostic skills. AI, particularly through convolutional neural networks, has improved image interpretation and diagnostic accuracy in oral radiology, leading to precise treatment planning. Oral surgery benefits from AR, VR, and MR in resident training, surgical procedures, and patient education, allowing for greater precision in surgery planning and ensuring patients comprehend expected outcomes. In oral pathology, AI-based image analysis provides consistent diagnostic reports, while VR and AR stimulators assist in teaching laboratory techniques and explaining histopathological features. However, these technologies have limitations, including the need for further validation and addressing ergonomic challenges and high costs. In conclusion, the integration of AI, VR, AR, MR, and XR into dentistry represents a transformative moment, empowering healthcare professionals to deliver superior care and cost savings. Ongoing research should focus on harnessing these tools in oral medicine, radiology, surgery, and pathology to fully unlock their potential in oral health care, promising a brighter, technologically enhanced future for dentistry.

The authors have declared that no competing interests exist.

TheScholarsRepository@LLU: Digital Archive of Research, Scholarship & Creative Works

Home > SD > DENTISTRY > ETD-PERIODONTICS

Theses, Dissertations and Projects - Periodontics

Theses/dissertations from 2022 2022.

A Study in Fresh Human Cadaver Heads Examining the Incidence of Maxillary Sinus Membrane Perforation During Crestal Sinus Elevation Comparing Osteotomes to Osseodensification Drills. , Thaer Alqadoumi

Titanium Particles within Mucosa during Non-Surgical Implant Debridement , Holvin Louie

Accuracy of Implant Placement Comparing a Tissue Level Static Guide vs. Dynamic Navigation Using the X-Mark Protocol on Edentulous Mandibles: A Laboratory Study , Nicholas Poovey

Theses/Dissertations from 2020 2020

A Comparison of Heat Generated Between Carbide and Diamond Bur during Implantoplasty , Bryce Chun

Comparison of Heat Generated During Twist Drilling Protocol by Guided and Non-Guided Implant Surgery , Joshua Lee

Theses/Dissertations from 2019 2019

Comparison of antimicrobial agents Ozonated Olive Oil and Chlorhexidine Gluconate - an in vitro study , Amelia David

Accuracy of Intraoral Scanners with Different Total Occlusal Convergence Angles: An In-Vitro Study , Brittany M. Pang

Theses/Dissertations from 2018 2018

A Digitized Comparison using Cone Beam Computed Tomography and Intraoral Scanning , Yvette Carrillo

Theses/Dissertations from 2017 2017

Comparison of Antibacterial Activity of Ozonated Olive Oil and Chlorhexidine Gluconate , Changmin Lee

Accuracy of a Newly Developed Guided Dental Implant Delivery System , Fallon D. Livingston

Theses/Dissertations from 2016 2016

Accuracy of Implants Placed with Surgical Guides: Thermoplastic vs. 3-D Printed , Caitlyn K. Bell

Accuracy of Volumetric Analysis Software Packages in Assessment of Tooth Volume Using CBCT , Saylee Nimbalkar

Influence of Low Temperature Degradation on Microstructural Integrity of Zirconia Dental Implants , Mona Monzavi Rahimi

Theses/Dissertations from 2014 2014

Novel Approach to Assess Periodontal Disease Severity Using Volumetric Analysis , Meera George Maveli

Factors Affecting Gingival Recession in the Esthetic Zone: A Human Cadaver Study , Christen Sather

Theses/Dissertations from 2012 2012

Identification of the Mandibular Nerve with CBCT Using a Nerve Marking Tool or Not , Myung Soo Choi

Theses/Dissertations from 2009 2009

Factors Influencing Contrast Resolution of Cone Beam CT Using the CB MercuRay , Roger M. Anderson

Theses/Dissertations from 2007 2007

Reproducibility of Two Non-Consecutive Scans Using a NewTom 3G; in Vitro Model , Hyoung Jin Park

Theses/Dissertations from 2006 2006

Training Program to Improve Estimation of Patients' Periodontal Pain Experience , Yoon Jeong Kim

Influence of Keratinized Mucosa, Bone Dimensions on Mucosal Recession and Bone Loss , Jeanette Keng Ling Chua

Theses/Dissertations from 2005 2005

Comparison of Different Methods of Assessing Ridge Width prior to Implant Placement , Lung-Cheng Chen

Resonance Frequency Analysis as a Determinant of Implant Initial Stability , Negar Tabandeh

Theses/Dissertations from 2004 2004

Pain Experienced by Patients during Periodontal Examination , Mohammed A. Al-Ajmi

Pain Experienced by Patients Using Thinner vs. Thicker Probes During Probing , Mohamed A. Hassan

Effect of Anti-TGFß1 and Pycnogenol® on Scar Formation in Rats , Pilseong Kim

Theses/Dissertations from 2003 2003

Healing Following Placement of a Subperiosteal Orthodontic Anchoring Device , Oliver Hoffmann

Assessment of Alveolar Bone Density Using Implant Insertion Resistance Torque , Scott Sangmoo Lee

Theses/Dissertations from 2002 2002

IL-10 and Alveolar Bone Loss , Abdulaziz Saud Al-Rasheed

Assessment of Human Alveolar Bone Density by Using Volumetric CT Machine , Prasit Aranyarachkul

Pain Experienced by Patients during Periodontal Recall Treatment , Thu-Diem Chung

Theses/Dissertations from 2001 2001

Probing Bone Level Measurements for Determination of the Depths of Class II Furcation Defects , Youngil Suh

Theses/Dissertations from 1998 1998

Regeneration In Periodontal Defects with rhBMP-2 : A Dosage Study , Paola Guglielmoni

Theses/Dissertations from 1996 1996

Bone Morphogenetic Proteins and Periodontal Repair , Michael B. Lee

Periodontal Repair in Dogs : Effect of Recombinant Human Transforming Growth Factor Beta-1 on Guided Tissue Regeneration , Saghi Shayan Razi

Theses/Dissertations from 1995 1995

Periodontal Repair in Dogs : Evaluation of rhBMP-2 Carriers , Lauralee Nygaard

Alveolar Bone and Cementum Regeneration Following Periodontal Reconstructive Therapy : A Review of Histologic Observations In Man and Experimental Animals , Karen E. Rodden

Theses/Dissertations from 1994 1994

Healing Following Periodontal Reconstructive Surgery : Surgical Implantation of a Collagen Matrix or Demineralized Freeze-dried Bone Allograft , Seong Yong Choi

Periodontal Repair in Dogs : Part I : Evaluation of the Natural Disease Model ; Part II : ePTFE Barrier Membranes Support Wound Stabilization and Enhance Bone Regeneration , James Marc Haney

Theses/Dissertations from 1993 1993

Reproducibility of Periodontal Probing , Su-Fang Wang

Theses/Dissertations from 1992 1992

Transforming Growth Factor-Beta 1 Expression in Developing Ovine Teeth as Visualized by In Situ Hybridization , Søren Jepsen

The Periodontal Intraosseous Defect Following Root Conditioning with Citric Acid and Wound Closure Including a PTFE Membrane : An Experimental Study , Betty Glaser Kersten

Theses/Dissertations from 1989 1989

The Effect of an Anti-Osteoclastic Agent and a Collagen Sponge on Root Resorption Following Regenerative Periodontal Surgery in the Dog , Rudolf Hahn

Theses/Dissertations from 1988 1988

Treatment of Periodontal Furcation Defects , Michael Martin and Bernard Gantes

Theses/Dissertations from 1987 1987

Treatment of Periodontal Furcation Defects , Bernard Gantes

Effects of Oral Hygiene Measures on Clinical and Microbiological Parameters of Periodontal Disease , Bruno Loos

Theses/Dissertations from 1984 1984

Predictions of the Effects of Nonsurgical Periodontial Therapy : Prospective and Retrospective Identification of Deteriorating Sites , Rik Achille Vanooteghem

Theses/Dissertations from 1982 1982

Healing Following Two Different Surgical Approaches to Treating Deep Periodontal Intraosseous Defects , A. Durwin H. Chamberlain

Theses/Dissertations from 1981 1981

The Effect of Mechanical Plaque Control on the Clinical Parameters of Human Periodontal Disease , John F. Cercek Jr.

Histologic Probe Position in Treated and Untreated Human Periodontal Tissues , Clifford Fowler

Theses/Dissertations from 1980 1980

Changes of the Marginal Periodontium as a Result of Labial Tooth Movement in Monkeys , Gregory G. Steiner, J. K. Pearson, and J. Ainamo

Evaluation of New Attachment Following Full Thickness Flap Procedure in Humans , Shaunda S. Steiner

Theses/Dissertations from 1978 1978

New Attachment of Connective Tissues to Human Teeth Involved in Chronic Periodontal Disease : A Histologic Study , Rick Cole

Ultrastructural Study of Wound Healing on a Root Planed and Citric Acid Treated Root Surface , Craig Martin Ririe

Theses/Dissertations from 1977 1977

A Comparison of a Step-by-Step versus an All-in-one Approach in Teaching Plaque Control , Charles R. Woofter

Theses/Dissertations from 1976 1976

The Effects of Topically Applied Citric Acid on Periodontally Diseased Root Surfaces , John S. Garrett

Gingival Condition in Areas of Minimal and Appreciable Widths of Keratinized Gingiva , Myles C. Miyasato

Theses/Dissertations from 1975 1975

Developing a Periodontal Screening Examination , Jeffrey R. Morgulis

The Effect of Chlorhexidine or Oxytetracycline Irrigation on the Subgingival Microbiota , George M. Whitehead

Theses/Dissertations from 1973 1973

The Effect of Post-Operative Use of Chlorhexidine on Periodontal Regeneration in Monkeys with Chronic Bifurcation Defects , J. Pat Bishop

Effect of Tooth Cleaning Procedures on Gingival Sulcus , Klaus D. Wolfram

Theses/Dissertations from 1972 1972

The Effect of Oral Allografts of Cancellous Bone and Marrow in Mice , George E. Deeb

Microscopic Evaluation of Topically Applied Chlorhexidine Gluconate on Gingival Wound Healing in Dogs , Robert C. Hirst

Marrow Isografts in the Oral Cavity of Mice , Robert L. Merin

Theses/Dissertations from 1971 1971

Root Exposure and its Effect on the Fluid Movement within the Tooth , William J. Busch

The Response of Gingival Tissues to Alterations in pH , Robert C. Jann

A Clinical and Microscopic Evaluation of Plaque Removal and by the Hydrodent Brush , Soertini E. Lambri

The Effect of Elevated Glucose on Neutrophilic Phagocytosis in Genetically Diabetic Mice , Larry B. Thompson

Theses/Dissertations from 1970 1970

An In Vivo Perfusion Apparatus for Studies on Gingival Disease in the Albino Rat : Assessment by a Perfusion of the Enzymes Collagenase and Hyaluronidase , James A. Smith

Theses/Dissertations from 1969 1969

An In Vivo Perfusion Apparatus for Studies on Gingival Disease : Assessment by a Perfusion of Nonspecific Proteolytic Enzymes , Don Dornan

The Effect of a Patient-Counseling Film and Hygienist on the Oral Hygiene of Junior High School Students , Leonard L. Espinda

Theses/Dissertations from 1968 1968

A Study of Alveolar Bone Loss and Two-Hour Postprandial Blood Sugar Levels , R. Leslie Arnett

Theses/Dissertations from 1967 1967

The Effect of Glucose on Neutrophilic Phagocytosis , Donald F. Adams

Theses/Dissertations from 1962 1962

The Pathogenesis of Periodontal Disease and Treatment Implications , Richard C. Oliver

• Collections
• Disciplines

Advanced Search

• Notify me via email or RSS

Author Corner

• Faculty Research (Pure)

Home | About | FAQ | My Account | Accessibility Statement

Privacy Copyright

• Future Students
• Current students
• Scholarships
• How to apply
• Research at UWA
• Courses and programs
• Research institutes and centres
• Media and experts
• Impact newsroom
• Find an expert
• Media enquiries
• Vice-Chancellor
• History of the University
• Official publications
• Communications and marketing
• Working at UWA
• Business & industry
• International engagement
• Alumni and Friends
• Perth Festival
• Filming and photography
• Giving to UWA
• General enquiries
• Staff directory
• Transport and parking
• Visitors Information Centre
• A -Z list of Websites

Oral Medicine & Pathology Research Group

Enhancing patient care in the field of oral diseases.

The aim of the “Oral Medicine & Pathology” research group is to promote research in the field of oral diseases covering their clinical and pathological research aspects. The ultimate goal is to enhance patient’s standard of care in the field of oral diseases. Our strategic philosophy is to equip our students with transferable research skills that would enable them to excel in their professional career. Our group members are nationally and internationally reputed for their outstanding contribution to the recent advances in the field of oral diseases.

Research Program Lead:  Dr Omar Kujan

Research areas

• Oral potentially malignant disorders
• Oral cancer
• Orofacial pain
• Salivary gland diseases
• Clinical care and education in the field of oral medicine and pathology
• Molecular pathology and genetics of oral carcinogenesis
• Oral mucosal lesions
• Odontogenic tumours

This program has been funded by grants from state and national organisations.

• National Health and Medical Research Council
• Australian Dental Research Foundation
• Colgate Industrial Partnership

Current Research Projects

• Efficacy of oral brush liquid-based cytology in the diagnosis of oral mucosal lesions
• Development and application of 3D organoid models for the investigation of oral carcinogenesis
• The potential malignancy of oral lichen planus
• Diagnostic and predictive biomarkers of oral potentially malignant disorders
• Chronic disease comorbidity in patients with oral leukoplakia
• Oral health and systemic diseases
• Orofacial pain and temporomandibular disorders 
• Dental education with focus on oral medicine and pathology education

Collaborators

• Dr Ali Syed Khurram, Unit of Oral & Maxillofacial Pathology, School of Clinical Dentistry, University of Sheffield, Sheffield, UK
• Emeritus Prof Paul Speight, Unit of Oral & Maxillofacial Pathology, School of Clinical Dentistry, University of Sheffield, Sheffield, UK
• Prof Mario Pérez-Sayáns, Oral Medicine, Oral Surgery and Implantology Unit- Faculty of Medicine and Odontology, University of Santiago de Compostela, Spain

Industry partners

Contact Program Lead Dr Omar Kujan

Get in touch

Send an enquiry

• My Shodhganga
• Receive email updates
• Edit Profile

Shodhganga : a reservoir of Indian theses @ INFLIBNET

• Shodhganga@INFLIBNET
• Homi Bhabha National Institute
• Department of Health Sciences

Items in Shodhganga are licensed under Creative Commons Licence Attribution-NonCommercial-ShareAlike 4.0 International (CC BY-NC-SA 4.0).

Head Start Your Radiology Residency [Online] ↗️

• Radiology Thesis – More than 400 Research Topics (2022)!

Username or Email Address

Remember Me

Introduction

A thesis or dissertation, as some people would like to call it, is an integral part of the Radiology curriculum, be it MD, DNB, or DMRD. We have tried to aggregate radiology thesis topics from various sources for reference.

Not everyone is interested in research, and writing a Radiology thesis can be daunting. But there is no escape from preparing, so it is better that you accept this bitter truth and start working on it instead of cribbing about it (like other things in life. #PhilosophyGyan!)

Start working on your thesis as early as possible and finish your thesis well before your exams, so you do not have that stress at the back of your mind. Also, your thesis may need multiple revisions, so be prepared and allocate time accordingly.

Tips for Choosing Radiology Thesis and Research Topics

Keep it simple silly (kiss).

Retrospective > Prospective

Retrospective studies are better than prospective ones, as you already have the data you need when choosing to do a retrospective study. Prospective studies are better quality, but as a resident, you may not have time (, energy and enthusiasm) to complete these.

Choose a simple topic that answers a single/few questions

Original research is challenging, especially if you do not have prior experience. I would suggest you choose a topic that answers a single or few questions. Most topics that I have listed are along those lines. Alternatively, you can choose a broad topic such as “Role of MRI in evaluation of perianal fistulas.”

You can choose a novel topic if you are genuinely interested in research AND have a good mentor who will guide you. Once you have done that, make sure that you publish your study once you are done with it.

Get it done ASAP.

In most cases, it makes sense to stick to a thesis topic that will not take much time. That does not mean you should ignore your thesis and ‘Ctrl C + Ctrl V’ from a friend from another university. Thesis writing is your first step toward research methodology so do it as sincerely as possible. Do not procrastinate in preparing the thesis. As soon as you have been allotted a guide, start researching topics and writing a review of the literature.

At the same time, do not invest a lot of time in writing/collecting data for your thesis. You should not be busy finishing your thesis a few months before the exam. Some people could not appear for the exam because they could not submit their thesis in time. So DO NOT TAKE thesis lightly.

Do NOT Copy-Paste

Reiterating once again, do not simply choose someone else’s thesis topic. Find out what are kind of cases that your Hospital caters to. It is better to do a good thesis on a common topic than a crappy one on a rare one.

Books to help you write a Radiology Thesis

Event country/university has a different format for thesis; hence these book recommendations may not work for everyone.

• Amazon Kindle Edition
• Gupta, Piyush (Author)
• English (Publication Language)
• 206 Pages - 10/12/2020 (Publication Date) - Jaypee Brothers Medical Publishers (P) Ltd. (Publisher)

In A Hurry? Download a PDF list of Radiology Research Topics!

Sign up below to get this PDF directly to your email address.

100% Privacy Guaranteed. Your information will not be shared. Unsubscribe anytime with a single click.

List of Radiology Research /Thesis / Dissertation Topics

• State of the art of MRI in the diagnosis of hepatic focal lesions
• Multimodality imaging evaluation of sacroiliitis in newly diagnosed patients of spondyloarthropathy
• Multidetector computed tomography in oesophageal varices
• Role of positron emission tomography with computed tomography in the diagnosis of cancer Thyroid
• Evaluation of focal breast lesions using ultrasound elastography
• Role of MRI diffusion tensor imaging in the assessment of traumatic spinal cord injuries
• Sonographic imaging in male infertility
• Comparison of color Doppler and digital subtraction angiography in occlusive arterial disease in patients with lower limb ischemia
• The role of CT urography in Haematuria
• Role of functional magnetic resonance imaging in making brain tumor surgery safer
• Prediction of pre-eclampsia and fetal growth restriction by uterine artery Doppler
• Role of grayscale and color Doppler ultrasonography in the evaluation of neonatal cholestasis
• Validity of MRI in the diagnosis of congenital anorectal anomalies
• Role of sonography in assessment of clubfoot
• Role of diffusion MRI in preoperative evaluation of brain neoplasms
• Imaging of upper airways for pre-anaesthetic evaluation purposes and for laryngeal afflictions.
• A study of multivessel (arterial and venous) Doppler velocimetry in intrauterine growth restriction
• Multiparametric 3tesla MRI of suspected prostatic malignancy.
• Role of Sonography in Characterization of Thyroid Nodules for differentiating benign from
• Role of advances magnetic resonance imaging sequences in multiple sclerosis
• Role of multidetector computed tomography in evaluation of jaw lesions
• Role of Ultrasound and MR Imaging in the Evaluation of Musculotendinous Pathologies of Shoulder Joint
• Role of perfusion computed tomography in the evaluation of cerebral blood flow, blood volume and vascular permeability of cerebral neoplasms
• MRI flow quantification in the assessment of the commonest csf flow abnormalities
• Role of diffusion-weighted MRI in evaluation of prostate lesions and its histopathological correlation
• CT enterography in evaluation of small bowel disorders
• Comparison of perfusion magnetic resonance imaging (PMRI), magnetic resonance spectroscopy (MRS) in and positron emission tomography-computed tomography (PET/CT) in post radiotherapy treated gliomas to detect recurrence
• Role of multidetector computed tomography in evaluation of paediatric retroperitoneal masses
• Role of Multidetector computed tomography in neck lesions
• Estimation of standard liver volume in Indian population
• Role of MRI in evaluation of spinal trauma
• Role of modified sonohysterography in female factor infertility: a pilot study.
• The role of pet-CT in the evaluation of hepatic tumors
• Role of 3D magnetic resonance imaging tractography in assessment of white matter tracts compromise in supratentorial tumors
• Role of dual phase multidetector computed tomography in gallbladder lesions
• Role of multidetector computed tomography in assessing anatomical variants of nasal cavity and paranasal sinuses in patients of chronic rhinosinusitis.
• magnetic resonance spectroscopy in multiple sclerosis
• Evaluation of thyroid nodules by ultrasound elastography using acoustic radiation force impulse (ARFI) imaging
• Role of Magnetic Resonance Imaging in Intractable Epilepsy
• Evaluation of suspected and known coronary artery disease by 128 slice multidetector CT.
• Role of regional diffusion tensor imaging in the evaluation of intracranial gliomas and its histopathological correlation
• Role of chest sonography in diagnosing pneumothorax
• Role of CT virtual cystoscopy in diagnosis of urinary bladder neoplasia
• Role of MRI in assessment of valvular heart diseases
• High resolution computed tomography of temporal bone in unsafe chronic suppurative otitis media
• Multidetector CT urography in the evaluation of hematuria
• Contrast-induced nephropathy in diagnostic imaging investigations with intravenous iodinated contrast media
• Comparison of dynamic susceptibility contrast-enhanced perfusion magnetic resonance imaging and single photon emission computed tomography in patients with little’s disease
• Role of Multidetector Computed Tomography in Bowel Lesions.
• Role of diagnostic imaging modalities in evaluation of post liver transplantation recipient complications.
• Role of multislice CT scan and barium swallow in the estimation of oesophageal tumour length
• Malignant Lesions-A Prospective Study.
• Value of ultrasonography in assessment of acute abdominal diseases in pediatric age group
• Role of three dimensional multidetector CT hysterosalpingography in female factor infertility
• Comparative evaluation of multi-detector computed tomography (MDCT) virtual tracheo-bronchoscopy and fiberoptic tracheo-bronchoscopy in airway diseases
• Role of Multidetector CT in the evaluation of small bowel obstruction
• Sonographic evaluation in adhesive capsulitis of shoulder
• Utility of MR Urography Versus Conventional Techniques in Obstructive Uropathy
• MRI of the postoperative knee
• Role of 64 slice-multi detector computed tomography in diagnosis of bowel and mesenteric injury in blunt abdominal trauma.
• Sonoelastography and triphasic computed tomography in the evaluation of focal liver lesions
• Evaluation of Role of Transperineal Ultrasound and Magnetic Resonance Imaging in Urinary Stress incontinence in Women
• Multidetector computed tomographic features of abdominal hernias
• Evaluation of lesions of major salivary glands using ultrasound elastography
• Transvaginal ultrasound and magnetic resonance imaging in female urinary incontinence
• MDCT colonography and double-contrast barium enema in evaluation of colonic lesions
• Role of MRI in diagnosis and staging of urinary bladder carcinoma
• Spectrum of imaging findings in children with febrile neutropenia.
• Spectrum of radiographic appearances in children with chest tuberculosis.
• Role of computerized tomography in evaluation of mediastinal masses in pediatric
• Diagnosing renal artery stenosis: Comparison of multimodality imaging in diabetic patients
• Role of multidetector CT virtual hysteroscopy in the detection of the uterine & tubal causes of female infertility
• Role of multislice computed tomography in evaluation of crohn’s disease
• CT quantification of parenchymal and airway parameters on 64 slice MDCT in patients of chronic obstructive pulmonary disease
• Comparative evaluation of MDCT  and 3t MRI in radiographically detected jaw lesions.
• Evaluation of diagnostic accuracy of ultrasonography, colour Doppler sonography and low dose computed tomography in acute appendicitis
• Ultrasonography , magnetic resonance cholangio-pancreatography (MRCP) in assessment of pediatric biliary lesions
• Multidetector computed tomography in hepatobiliary lesions.
• Evaluation of peripheral nerve lesions with high resolution ultrasonography and colour Doppler
• Multidetector computed tomography in pancreatic lesions
• Multidetector Computed Tomography in Paediatric abdominal masses.
• Evaluation of focal liver lesions by colour Doppler and MDCT perfusion imaging
• Sonographic evaluation of clubfoot correction during Ponseti treatment
• Role of multidetector CT in characterization of renal masses
• Study to assess the role of Doppler ultrasound in evaluation of arteriovenous (av) hemodialysis fistula and the complications of hemodialysis vasular access
• Comparative study of multiphasic contrast-enhanced CT and contrast-enhanced MRI in the evaluation of hepatic mass lesions
• Sonographic spectrum of rheumatoid arthritis
• Diagnosis & staging of liver fibrosis by ultrasound elastography in patients with chronic liver diseases
• Role of multidetector computed tomography in assessment of jaw lesions.
• Role of high-resolution ultrasonography in the differentiation of benign and malignant thyroid lesions
• Radiological evaluation of aortic aneurysms in patients selected for endovascular repair
• Role of conventional MRI, and diffusion tensor imaging tractography in evaluation of congenital brain malformations
• To evaluate the status of coronary arteries in patients with non-valvular atrial fibrillation using 256 multirow detector CT scan
• A comparative study of ultrasonography and CT – arthrography in diagnosis of chronic ligamentous and meniscal injuries of knee
• Multi detector computed tomography evaluation in chronic obstructive pulmonary disease and correlation with severity of disease
• Diffusion weighted and dynamic contrast enhanced magnetic resonance imaging in chemoradiotherapeutic response evaluation in cervical cancer.
• High resolution sonography in the evaluation of non-traumatic painful wrist
• The role of trans-vaginal ultrasound versus magnetic resonance imaging in diagnosis & evaluation of cancer cervix
• Role of multidetector row computed tomography in assessment of maxillofacial trauma
• Imaging of vascular complication after liver transplantation.
• Role of magnetic resonance perfusion weighted imaging & spectroscopy for grading of glioma by correlating perfusion parameter of the lesion with the final histopathological grade
• Magnetic resonance evaluation of abdominal tuberculosis.
• Diagnostic usefulness of low dose spiral HRCT in diffuse lung diseases
• Role of dynamic contrast enhanced and diffusion weighted magnetic resonance imaging in evaluation of endometrial lesions
• Contrast enhanced digital mammography anddigital breast tomosynthesis in early diagnosis of breast lesion
• Evaluation of Portal Hypertension with Colour Doppler flow imaging and magnetic resonance imaging
• Evaluation of musculoskeletal lesions by magnetic resonance imaging
• Role of diffusion magnetic resonance imaging in assessment of neoplastic and inflammatory brain lesions
• Radiological spectrum of chest diseases in HIV infected children High resolution ultrasonography in neck masses in children
• with surgical findings
• Sonographic evaluation of peripheral nerves in type 2 diabetes mellitus.
• Role of perfusion computed tomography in the evaluation of neck masses and correlation
• Role of ultrasonography in the diagnosis of knee joint lesions
• Role of ultrasonography in evaluation of various causes of pelvic pain in first trimester of pregnancy.
• Role of Magnetic Resonance Angiography in the Evaluation of Diseases of Aorta and its Branches
• MDCT fistulography in evaluation of fistula in Ano
• Role of multislice CT in diagnosis of small intestine tumors
• Role of high resolution CT in differentiation between benign and malignant pulmonary nodules in children
• A study of multidetector computed tomography urography in urinary tract abnormalities
• Role of high resolution sonography in assessment of ulnar nerve in patients with leprosy.
• Pre-operative radiological evaluation of locally aggressive and malignant musculoskeletal tumours by computed tomography and magnetic resonance imaging.
• The role of ultrasound & MRI in acute pelvic inflammatory disease
• Ultrasonography compared to computed tomographic arthrography in the evaluation of shoulder pain
• Role of Multidetector Computed Tomography in patients with blunt abdominal trauma.
• The Role of Extended field-of-view Sonography and compound imaging in Evaluation of Breast Lesions
• Evaluation of focal pancreatic lesions by Multidetector CT and perfusion CT
• Evaluation of breast masses on sono-mammography and colour Doppler imaging
• Role of CT virtual laryngoscopy in evaluation of laryngeal masses
• Triple phase multi detector computed tomography in hepatic masses
• Role of transvaginal ultrasound in diagnosis and treatment of female infertility
• Role of ultrasound and color Doppler imaging in assessment of acute abdomen due to female genetal causes
• High resolution ultrasonography and color Doppler ultrasonography in scrotal lesion
• Evaluation of diagnostic accuracy of ultrasonography with colour Doppler vs low dose computed tomography in salivary gland disease
• Role of multidetector CT in diagnosis of salivary gland lesions
• Comparison of diagnostic efficacy of ultrasonography and magnetic resonance cholangiopancreatography in obstructive jaundice: A prospective study
• Evaluation of varicose veins-comparative assessment of low dose CT venogram with sonography: pilot study
• Role of mammotome in breast lesions
• The role of interventional imaging procedures in the treatment of selected gynecological disorders
• Role of transcranial ultrasound in diagnosis of neonatal brain insults
• Role of multidetector CT virtual laryngoscopy in evaluation of laryngeal mass lesions
• Evaluation of adnexal masses on sonomorphology and color Doppler imaginig
• Role of radiological imaging in diagnosis of endometrial carcinoma
• Comprehensive imaging of renal masses by magnetic resonance imaging
• The role of 3D & 4D ultrasonography in abnormalities of fetal abdomen
• Diffusion weighted magnetic resonance imaging in diagnosis and characterization of brain tumors in correlation with conventional MRI
• Role of diffusion weighted MRI imaging in evaluation of cancer prostate
• Role of multidetector CT in diagnosis of urinary bladder cancer
• Role of multidetector computed tomography in the evaluation of paediatric retroperitoneal masses.
• Comparative evaluation of gastric lesions by double contrast barium upper G.I. and multi detector computed tomography
• Evaluation of hepatic fibrosis in chronic liver disease using ultrasound elastography
• Role of MRI in assessment of hydrocephalus in pediatric patients
• The role of sonoelastography in characterization of breast lesions
• The influence of volumetric tumor doubling time on survival of patients with intracranial tumours
• Role of perfusion computed tomography in characterization of colonic lesions
• Role of proton MRI spectroscopy in the evaluation of temporal lobe epilepsy
• Role of Doppler ultrasound and multidetector CT angiography in evaluation of peripheral arterial diseases.
• Role of multidetector computed tomography in paranasal sinus pathologies
• Role of virtual endoscopy using MDCT in detection & evaluation of gastric pathologies
• High resolution 3 Tesla MRI in the evaluation of ankle and hindfoot pain.
• Transperineal ultrasonography in infants with anorectal malformation
• CT portography using MDCT versus color Doppler in detection of varices in cirrhotic patients
• Role of CT urography in the evaluation of a dilated ureter
• Characterization of pulmonary nodules by dynamic contrast-enhanced multidetector CT
• Comprehensive imaging of acute ischemic stroke on multidetector CT
• The role of fetal MRI in the diagnosis of intrauterine neurological congenital anomalies
• Role of Multidetector computed tomography in pediatric chest masses
• Multimodality imaging in the evaluation of palpable & non-palpable breast lesion.
• Sonographic Assessment Of Fetal Nasal Bone Length At 11-28 Gestational Weeks And Its Correlation With Fetal Outcome.
• Role Of Sonoelastography And Contrast-Enhanced Computed Tomography In Evaluation Of Lymph Node Metastasis In Head And Neck Cancers
• Role Of Renal Doppler And Shear Wave Elastography In Diabetic Nephropathy
• Evaluation Of Relationship Between Various Grades Of Fatty Liver And Shear Wave Elastography Values
• Evaluation and characterization of pelvic masses of gynecological origin by USG, color Doppler and MRI in females of reproductive age group
• Radiological evaluation of small bowel diseases using computed tomographic enterography
• Role of coronary CT angiography in patients of coronary artery disease
• Role of multimodality imaging in the evaluation of pediatric neck masses
• Role of CT in the evaluation of craniocerebral trauma
• Role of magnetic resonance imaging (MRI) in the evaluation of spinal dysraphism
• Comparative evaluation of triple phase CT and dynamic contrast-enhanced MRI in patients with liver cirrhosis
• Evaluation of the relationship between carotid intima-media thickness and coronary artery disease in patients evaluated by coronary angiography for suspected CAD
• Assessment of hepatic fat content in fatty liver disease by unenhanced computed tomography
• Correlation of vertebral marrow fat on spectroscopy and diffusion-weighted MRI imaging with bone mineral density in postmenopausal women.
• Comparative evaluation of CT coronary angiography with conventional catheter coronary angiography
• Ultrasound evaluation of kidney length & descending colon diameter in normal and intrauterine growth-restricted fetuses
• A prospective study of hepatic vein waveform and splenoportal index in liver cirrhosis: correlation with child Pugh’s classification and presence of esophageal varices.
• CT angiography to evaluate coronary artery by-pass graft patency in symptomatic patient’s functional assessment of myocardium by cardiac MRI in patients with myocardial infarction
• MRI evaluation of HIV positive patients with central nervous system manifestations
• MDCT evaluation of mediastinal and hilar masses
• Evaluation of rotator cuff & labro-ligamentous complex lesions by MRI & MRI arthrography of shoulder joint
• Role of imaging in the evaluation of soft tissue vascular malformation
• Role of MRI and ultrasonography in the evaluation of multifidus muscle pathology in chronic low back pain patients
• Role of ultrasound elastography in the differential diagnosis of breast lesions
• Role of magnetic resonance cholangiopancreatography in evaluating dilated common bile duct in patients with symptomatic gallstone disease.
• Comparative study of CT urography & hybrid CT urography in patients with haematuria.
• Role of MRI in the evaluation of anorectal malformations
• Comparison of ultrasound-Doppler and magnetic resonance imaging findings in rheumatoid arthritis of hand and wrist
• Role of Doppler sonography in the evaluation of renal artery stenosis in hypertensive patients undergoing coronary angiography for coronary artery disease.
• Comparison of radiography, computed tomography and magnetic resonance imaging in the detection of sacroiliitis in ankylosing spondylitis.
• Mr evaluation of painful hip
• Role of MRI imaging in pretherapeutic assessment of oral and oropharyngeal malignancy
• Evaluation of diffuse lung diseases by high resolution computed tomography of the chest
• Mr evaluation of brain parenchyma in patients with craniosynostosis.
• Diagnostic and prognostic value of cardiovascular magnetic resonance imaging in dilated cardiomyopathy
• Role of multiparametric magnetic resonance imaging in the detection of early carcinoma prostate
• Role of magnetic resonance imaging in white matter diseases
• Role of sonoelastography in assessing the response to neoadjuvant chemotherapy in patients with locally advanced breast cancer.
• Role of ultrasonography in the evaluation of carotid and femoral intima-media thickness in predialysis patients with chronic kidney disease
• Role of H1 MRI spectroscopy in focal bone lesions of peripheral skeleton choline detection by MRI spectroscopy in breast cancer and its correlation with biomarkers and histological grade.
• Ultrasound and MRI evaluation of axillary lymph node status in breast cancer.
• Role of sonography and magnetic resonance imaging in evaluating chronic lateral epicondylitis.
• Comparative of sonography including Doppler and sonoelastography in cervical lymphadenopathy.
• Evaluation of Umbilical Coiling Index as Predictor of Pregnancy Outcome.
• Computerized Tomographic Evaluation of Azygoesophageal Recess in Adults.
• Lumbar Facet Arthropathy in Low Backache.
• “Urethral Injuries After Pelvic Trauma: Evaluation with Uretrography
• Role Of Ct In Diagnosis Of Inflammatory Renal Diseases
• Role Of Ct Virtual Laryngoscopy In Evaluation Of Laryngeal Masses
• “Ct Portography Using Mdct Versus Color Doppler In Detection Of Varices In
• Cirrhotic Patients”
• Role Of Multidetector Ct In Characterization Of Renal Masses
• Role Of Ct Virtual Cystoscopy In Diagnosis Of Urinary Bladder Neoplasia
• Role Of Multislice Ct In Diagnosis Of Small Intestine Tumors
• “Mri Flow Quantification In The Assessment Of The Commonest CSF Flow Abnormalities”
• “The Role Of Fetal Mri In Diagnosis Of Intrauterine Neurological CongenitalAnomalies”
• Role Of Transcranial Ultrasound In Diagnosis Of Neonatal Brain Insults
• “The Role Of Interventional Imaging Procedures In The Treatment Of Selected Gynecological Disorders”
• Role Of Radiological Imaging In Diagnosis Of Endometrial Carcinoma
• “Role Of High-Resolution Ct In Differentiation Between Benign And Malignant Pulmonary Nodules In Children”
• Role Of Ultrasonography In The Diagnosis Of Knee Joint Lesions
• “Role Of Diagnostic Imaging Modalities In Evaluation Of Post Liver Transplantation Recipient Complications”
• “Diffusion-Weighted Magnetic Resonance Imaging In Diagnosis And
• Characterization Of Brain Tumors In Correlation With Conventional Mri”
• The Role Of PET-CT In The Evaluation Of Hepatic Tumors
• “Role Of Computerized Tomography In Evaluation Of Mediastinal Masses In Pediatric patients”
• “Trans Vaginal Ultrasound And Magnetic Resonance Imaging In Female Urinary Incontinence”
• Role Of Multidetector Ct In Diagnosis Of Urinary Bladder Cancer
• “Role Of Transvaginal Ultrasound In Diagnosis And Treatment Of Female Infertility”
• Role Of Diffusion-Weighted Mri Imaging In Evaluation Of Cancer Prostate
• “Role Of Positron Emission Tomography With Computed Tomography In Diagnosis Of Cancer Thyroid”
• The Role Of CT Urography In Case Of Haematuria
• “Value Of Ultrasonography In Assessment Of Acute Abdominal Diseases In Pediatric Age Group”
• “Role Of Functional Magnetic Resonance Imaging In Making Brain Tumor Surgery Safer”
• The Role Of Sonoelastography In Characterization Of Breast Lesions
• “Ultrasonography, Magnetic Resonance Cholangiopancreatography (MRCP) In Assessment Of Pediatric Biliary Lesions”
• “Role Of Ultrasound And Color Doppler Imaging In Assessment Of Acute Abdomen Due To Female Genital Causes”
• “Role Of Multidetector Ct Virtual Laryngoscopy In Evaluation Of Laryngeal Mass Lesions”
• MRI Of The Postoperative Knee
• Role Of Mri In Assessment Of Valvular Heart Diseases
• The Role Of 3D & 4D Ultrasonography In Abnormalities Of Fetal Abdomen
• State Of The Art Of Mri In Diagnosis Of Hepatic Focal Lesions
• Role Of Multidetector Ct In Diagnosis Of Salivary Gland Lesions
• “Role Of Virtual Endoscopy Using Mdct In Detection & Evaluation Of Gastric Pathologies”
• The Role Of Ultrasound & Mri In Acute Pelvic Inflammatory Disease
• “Diagnosis & Staging Of Liver Fibrosis By Ultraso Und Elastography In
• Patients With Chronic Liver Diseases”
• Role Of Mri In Evaluation Of Spinal Trauma
• Validity Of Mri In Diagnosis Of Congenital Anorectal Anomalies
• Imaging Of Vascular Complication After Liver Transplantation
• “Contrast-Enhanced Digital Mammography And Digital Breast Tomosynthesis In Early Diagnosis Of Breast Lesion”
• Role Of Mammotome In Breast Lesions
• “Role Of MRI Diffusion Tensor Imaging (DTI) In Assessment Of Traumatic Spinal Cord Injuries”
• “Prediction Of Pre-eclampsia And Fetal Growth Restriction By Uterine Artery Doppler”
• “Role Of Multidetector Row Computed Tomography In Assessment Of Maxillofacial Trauma”
• “Role Of Diffusion Magnetic Resonance Imaging In Assessment Of Neoplastic And Inflammatory Brain Lesions”
• Role Of Diffusion Mri In Preoperative Evaluation Of Brain Neoplasms
• “Role Of Multidetector Ct Virtual Hysteroscopy In The Detection Of The
• Uterine & Tubal Causes Of Female Infertility”
• Role Of Advances Magnetic Resonance Imaging Sequences In Multiple Sclerosis Magnetic Resonance Spectroscopy In Multiple Sclerosis
• “Role Of Conventional Mri, And Diffusion Tensor Imaging Tractography In Evaluation Of Congenital Brain Malformations”
• Role Of MRI In Evaluation Of Spinal Trauma
• Diagnostic Role Of Diffusion-weighted MR Imaging In Neck Masses
• “The Role Of Transvaginal Ultrasound Versus Magnetic Resonance Imaging In Diagnosis & Evaluation Of Cancer Cervix”
• “Role Of 3d Magnetic Resonance Imaging Tractography In Assessment Of White Matter Tracts Compromise In Supra Tentorial Tumors”
• Role Of Proton MR Spectroscopy In The Evaluation Of Temporal Lobe Epilepsy
• Role Of Multislice Computed Tomography In Evaluation Of Crohn’s Disease
• Role Of MRI In Assessment Of Hydrocephalus In Pediatric Patients
• The Role Of MRI In Diagnosis And Staging Of Urinary Bladder Carcinoma
• USG and MRI correlation of congenital CNS anomalies
• HRCT in interstitial lung disease
• X-Ray, CT and MRI correlation of bone tumors
• “Study on the diagnostic and prognostic utility of X-Rays for cases of pulmonary tuberculosis under RNTCP”
• “Role of magnetic resonance imaging in the characterization of female adnexal  pathology”
• “CT angiography of carotid atherosclerosis and NECT brain in cerebral ischemia, a correlative analysis”
• Role of CT scan in the evaluation of paranasal sinus pathology
• USG and MRI correlation on shoulder joint pathology
• “Radiological evaluation of a patient presenting with extrapulmonary tuberculosis”
• CT and MRI correlation in focal liver lesions”
• Comparison of MDCT virtual cystoscopy with conventional cystoscopy in bladder tumors”
• “Bleeding vessels in life-threatening hemoptysis: Comparison of 64 detector row CT angiography with conventional angiography prior to endovascular management”
• “Role of transarterial chemoembolization in unresectable hepatocellular carcinoma”
• “Comparison of color flow duplex study with digital subtraction angiography in the evaluation of peripheral vascular disease”
• “A Study to assess the efficacy of magnetization transfer ratio in differentiating tuberculoma from neurocysticercosis”
• “MR evaluation of uterine mass lesions in correlation with transabdominal, transvaginal ultrasound using HPE as a gold standard”
• “The Role of power Doppler imaging with trans rectal ultrasonogram guided prostate biopsy in the detection of prostate cancer”
• “Lower limb arteries assessed with doppler angiography – A prospective comparative study with multidetector CT angiography”
• “Comparison of sildenafil with papaverine in penile doppler by assessing hemodynamic changes”
• “Evaluation of efficacy of sonosalphingogram for assessing tubal patency in infertile patients with hysterosalpingogram as the gold standard”
• Role of CT enteroclysis in the evaluation of small bowel diseases
• “MRI colonography versus conventional colonoscopy in the detection of colonic polyposis”
• “Magnetic Resonance Imaging of anteroposterior diameter of the midbrain – differentiation of progressive supranuclear palsy from Parkinson disease”
• “MRI Evaluation of anterior cruciate ligament tears with arthroscopic correlation”
• “The Clinicoradiological profile of cerebral venous sinus thrombosis with prognostic evaluation using MR sequences”
• “Role of MRI in the evaluation of pelvic floor integrity in stress incontinent patients” “Doppler ultrasound evaluation of hepatic venous waveform in portal hypertension before and after propranolol”
• “Role of transrectal sonography with colour doppler and MRI in evaluation of prostatic lesions with TRUS guided biopsy correlation”
• “Ultrasonographic evaluation of painful shoulders and correlation of rotator cuff pathologies and clinical examination”
• “Colour Doppler Evaluation of Common Adult Hepatic tumors More Than 2 Cm  with HPE and CECT Correlation”
• “Clinical Relevance of MR Urethrography in Obliterative Posterior Urethral Stricture”
• “Prediction of Adverse Perinatal Outcome in Growth Restricted Fetuses with Antenatal Doppler Study”
• Radiological evaluation of spinal dysraphism using CT and MRI
• “Evaluation of temporal bone in cholesteatoma patients by high resolution computed tomography”
• “Radiological evaluation of primary brain tumours using computed tomography and magnetic resonance imaging”
• “Three dimensional colour doppler sonographic assessment of changes in  volume and vascularity of fibroids – before and after uterine artery embolization”
• “In phase opposed phase imaging of bone marrow differentiating neoplastic lesions”
• “Role of dynamic MRI in replacing the isotope renogram in the functional evaluation of PUJ obstruction”
• Characterization of adrenal masses with contrast-enhanced CT – washout study
• A study on accuracy of magnetic resonance cholangiopancreatography
• “Evaluation of median nerve in carpal tunnel syndrome by high-frequency ultrasound & color doppler in comparison with nerve conduction studies”
• “Correlation of Agatston score in patients with obstructive and nonobstructive coronary artery disease following STEMI”
• “Doppler ultrasound assessment of tumor vascularity in locally advanced breast cancer at diagnosis and following primary systemic chemotherapy.”
• “Validation of two-dimensional perineal ultrasound and dynamic magnetic resonance imaging in pelvic floor dysfunction.”
• “Role of MR urethrography compared to conventional urethrography in the surgical management of obliterative urethral stricture.”

Search Diagnostic Imaging Research Topics

You can also search research-related resources and direct download PDFs for radiology articles on our custom radiology search engine .

Free Resources for Preparing Radiology Thesis

• Radiology thesis topics- Benha University – Free to download thesis
• Radiology thesis topics – Faculty of Medical Science Delhi
• Radiology thesis topics – IPGMER
• Fetal Radiology thesis Protocols
• Radiology thesis and dissertation topics
• Radiographics

Proofreading Your Thesis:

Make sure you use Grammarly to correct your spelling ,  grammar , and plagiarism for your thesis. Grammarly has affordable paid subscriptions, windows/macOS apps, and FREE browser extensions. It is an excellent tool to avoid inadvertent spelling mistakes in your research projects. It has an extensive built-in vocabulary, but you should make an account and add your own medical glossary to it.

Guidelines for Writing a Radiology Thesis:

These are general guidelines and not about radiology specifically. You can share these with colleagues from other departments as well. Special thanks to Dr. Sanjay Yadav sir for these. This section is best seen on a desktop. Here are a couple of handy presentations to start writing a thesis:

Read the general guidelines for writing a thesis (the page will take some time to load- more than 70 pages!

A format for thesis protocol with a sample patient information sheet, sample patient consent form, sample application letter for thesis, and sample certificate.

Resources and References:

• Guidelines for thesis writing.
• Format for thesis protocol
• Thesis protocol writing guidelines DNB
• Informed consent form for Research studies from AIIMS 
• Radiology Informed consent forms in local Indian languages.
• Sample Informed Consent form for Research in Hindi
• Guide to write a thesis by Dr. P R Sharma
• Guidelines for thesis writing by Dr. Pulin Gupta.
• Preparing MD/DNB thesis by A Indrayan
• Another good thesis reference protocol

Hopefully, this post will make the tedious task of writing a Radiology thesis a little bit easier for you. Best of luck with writing your thesis and your residency too!

More guides for residents :

• Guide for the MD/DMRD/DNB radiology exam!
• Guide for First-Year Radiology Residents
• FRCR Exam: THE Most Comprehensive Guide (2022)!
• Radiology Practical Exams Questions compilation for MD/DNB/DMRD !

Radiology Exam Resources (Oral Recalls, Instruments, etc )!

• Tips and Tricks for DNB/MD Radiology Practical Exam
• FRCR 2B exam- Tips and Tricks !
• FRCR exam preparation – An alternative take!
• Why did I take up Radiology?
• Radiology Conferences – A comprehensive guide!
• ECR (European Congress Of Radiology)
• European Diploma in Radiology (EDiR) – The Complete Guide!

Radiology NEET PG guide – How to select THE best college for post-graduation in Radiology (includes personal insights)!

• Interventional Radiology – All Your Questions Answered!
• What It Means To Be A Radiologist: A Guide For Medical Students!
• Radiology Mentors for Medical Students (Post NEET-PG)
• MD vs DNB Radiology: Which Path is Right for Your Career?
• DNB Radiology OSCE – Tips and Tricks

More radiology resources here: Radiology resources This page will be updated regularly. Kindly leave your feedback in the comments or send us a message here . Also, you can comment below regarding your department’s thesis topics.

Note: All topics have been compiled from available online resources. If anyone has an issue with any radiology thesis topics displayed here, you can message us here , and we can delete them. These are only sample guidelines. Thesis guidelines differ from institution to institution.

Image source: Thesis complete! (2018). Flickr. Retrieved 12 August 2018, from https://www.flickr.com/photos/cowlet/354911838 by Victoria Catterson

About The Author

Dr. amar udare, md, related posts ↓.

9 thoughts on “Radiology Thesis – More than 400 Research Topics (2022)!”

Amazing & The most helpful site for Radiology residents…

Thank you for your kind comments 🙂

Dr. I saw your Tips is very amazing and referable. But Dr. Can you help me with the thesis of Evaluation of Diagnostic accuracy of X-ray radiograph in knee joint lesion.

Wow! These are excellent stuff. You are indeed a teacher. God bless

Glad you liked these!

happy to see this

Glad I could help :).

Greetings Dr, thanks for your constant guides. pls Dr, I need a thesis research material on “Retrieving information from scattered photons in medical imaging”

Hey! Unfortunately I do not have anything relevant to that thesis topic.

Leave a Comment Cancel Reply

Your email address will not be published. Required fields are marked *

Get Radiology Updates to Your Inbox!

This site is for use by medical professionals. To continue, you must accept our use of cookies and the site's Terms of Use. Learn more Accept!

Wish to be a BETTER Radiologist? Join 14000 Radiology Colleagues !

Enter your email address below to access HIGH YIELD radiology content, updates, and resources.

No spam, only VALUE! Unsubscribe anytime with a single click.

Home > FACULTIES > Pathology > PATHOL-ETD

Pathology Theses and Dissertations

This collection contains theses and dissertations from the Department of Pathology, collected from the Scholarship@Western Electronic Thesis and Dissertation Repository

Theses/Dissertations from 2024 2024

The role of gut microbiome on the immunogenicity of immune hot neuroblastoma tumours , Hasti Gholami

Theses/Dissertations from 2023 2023

Investigation of Novel Pan-RAF Inhibitors in Anaplastic Thyroid Cancer , Sarah EB Ryan

Theses/Dissertations from 2022 2022

Evaluating the utility of S100A7 in identifying oral dysplastic lesions that will progress to oral squamous cell carcinoma , Jeff Soparlo

Theses/Dissertations from 2021 2021

Investigating The Impact Of The COVID-19 Pandemic On Maternal Perceived Stress, Postpartum Depressive Symptoms, And Pregnancy Outcomes In London, Ontario: A One Health Approach , Mei Yuan

Theses/Dissertations from 2020 2020

Evidence of an Antigen Presenting Cell Phenotype in Granular Cell Tumours , Benjamin J W A Rogala

Theses/Dissertations from 2019 2019

Junctophilin-2 Protects Cardiomyocytes against Palmitate-induced Injury , Xiaoyun Ji

Evaluating the Utility of Protein Biomarker, S100A7, and Diagnostic Test, Straticyte, in Predicting the Progression of Oral Dysplasia , Lachlan McLean

Alpha-Synuclein Toxicity is Caused by Mitochondrial Dysfunction , Michael G. Tauro

Theses/Dissertations from 2018 2018

Non-Cancerous Abnormalities That Could Mimic Prostate Cancer Like Signal in Multi-Parametric MRI Images , Mena Gaed

Mitochondrial permeability regulates cardiac endothelial cell necroptosis and cardiac allograft rejection , Ingrid Gan

Kallikrein-Related Peptidases are Dysregulated in Pleomorphic Adenoma , Matthew D. Morrison

Increased Mitochondrial Calpain-1 Is an Important Mechanism Contributing to Mitochondrial ROS Generation in Cardiac Diseases , Rui Ni

Elucidating mechanisms of innate and acquired resistance to PI3Ka inhibition in head and neck squamous cell carcinoma , Kara M. Ruicci

The Effects of Child Restraint System Use and Motor Vehicle Collision Severity on Injury Patterns and Severity in Children 8 Years Old and Younger. , Peyton A. Schroeder

Role of Long Noncoding RNAs in Diabetic Complications , Anu Alice Thomas

Effect of Estrogen and Glucocorticoid Signaling on Th2 cells – Implications for Severe Asthma , Meerah Vijeyakumaran

Theses/Dissertations from 2017 2017

CRISPR Screen for Identification of Kinases that Mediate Prostate Cancer Cell Invasion , Hamad Aldhafeeri

Immunological Impact of CLI-095 on Dendritic Cell Maturation and Hypoxia-re-oxygenation induced inflammatory injury , Hajed Obaid Alharbi

ERK5 Expression in Brain Tumours , Reem Ansari

Expression of Human Tissue Kallikreins (KLKs) in Polymorphous Low Grade Adenocarcinoma (PLGA) , Jacqueline M. Cox

A Clinico-Pathological Study of the Structural and Functional Changes in the Retina and Optic Nerve Following Diabetic Retinopathy Treatments , Richard Filek

Mechanisms underlying chemotherapy-induced vascular proliferation in ovarian cancer , Zeynep Gülsüm Kahramanoğlu

The Effect of Glucocorticosteroids on Th2 cells , Tharsan Kanagalingam

Hsp90 and its Co-chaperones Modify TDP-43 Localization, Aggregation, and Toxicity , Lilian T. Lin

Characterization of Hemangioma-initiating Stem Cells , Natalie Montwill

Postnatal β1 Integrin Deficiency in Pancreatic Beta-Cells Impairs Function and Survival , Jason E. Peart

Up-regulation of junctophilin-2 prevents ER stress and apoptosis in hypoxia/reoxygenation-stimulated H9c2 cells , Zijun Su

Theses/Dissertations from 2016 2016

Body and Organ Measurements in Infants and Neonates: An Autopsy Study , Audrey-Ann M. Evetts

The Long Non-coding RNA Malat1 Regulates Inflammatory Cytokine Production in Chronic Diabetic Complications , Andrew D. Gordon

Expression of Kallikrein-Related Peptidases (KLKs) in Adenoid Cystic Carcinoma , Zachary R. Kerr

Mechanisms regulating stem cell phenotype in infantile hemangioma , Niamh Richmond

Etiology of Motor Vehicle Collision Fatalities in Urban and Rural Canada , James R. Roos

Identification of a Nuclear Localization Signal (NLS) within the Pleckstrin Homology (PH) domain of Rho Guanine Nucleotide Exchange Factor (RGNEF) , Michael V. Tavolieri

Development and Performance Evaluation of an Antibody-Based Technology for Detection of E. coli O157 in Meat Samples and Its Potential Evolution Using Antibody Engineering , Yadira Tejeda Saldaña

Regulation of Phosphatase and Tensin Homolog Expression and Activity by Transforming Growth-Factor Beta in the Trabecular Meshwork Cells: Implications for Primary Open Angle Glaucoma , Nikoleta Tellios

Theses/Dissertations from 2015 2015

Phase II Clinical Trial of Concurrent Neoadjuvant Chemotherapy With Radiotherapy in Locally Advanced Breast Cancer , Muriel Brackstone

Expression Of Human Kallikrein Protein And mRNA In Maxillofacial Cysts And Tumours , Karl Kevin Cuddy

Chromatin Structure and Differential Accessibility of Homologous Human Mitotic Metaphase Chromosomes , Wahab A. Khan

β-adrenergic receptor-dependent and -independent effects of propranolol in infantile hemangioma , Jina J.Y. Kum

CD4+ T-cell Mediated Microvascular Endothelial Cell Death and Chronic Cardiac Allograft Rejection Involves Necroptosis , Cecilia YT Kwok

Epithelial to mesenchymal transition in the metastatic progression of gastroenteropancreatic neuroendocrine tumours , Stephanie Mok

Protective Effect of Modified Human Fibroblast Growth Factor on Diabetic Nephropathy , Ana M. Pena Diaz

Diabetic Bone Marrow & Stem Cell Dysfunction , Meghan A. Piccinin

Investigation of Pancreatic β-Cell Insulin Receptor Regulation of β-Cell Growth, Function, and Survival Via a Temporal Conditional Knockout , Liangyi Zhou

Theses/Dissertations from 2014 2014

The Role Of The RNA-Binding Protein Rho Guanine Nucleotide Exchange Factor In The Cellular Stress Response , Kevin WH Cheung

Exposure to Environmental Contaminants and Stress as Determinants of Health in Three Communities: Walpole Island and Attawapiskat First Nations and Naivasha, Kenya , Deirdre Phaedra Henley

miRNA Regulation of Programmed Cell Death-1 in T Cells: Potential Prognostic and Therapeutic Markers in Melanoma , Nathan J. Johnston

Cell Death Regulates Injury and Inflammation During Renal Allograft Transplantation , Arthur Lau

Role of SIRT1 in Vascular Complications of Diabetes , Rokhsana Mortuza

RIPK3 Regulates Microvascular Endothelial Cell Necroptosis and Cardiac Allograft Rejection , Alexander William Pavlosky

The Role of Integrins in Support of Pancreatic Function, Survival and Maturation , Matthew Riopel

Polycomb Repressive Complex 2 Regulates miR-200b in Retinal Endothelial Cells: Possible Implications in Diabetic Retinopathy , Michael A. Ruiz

Association of Head and Cervical Injuries in Pediatric Occupants Involved in Motor Vehicle Collisions , Shayan Shekari

Development of Non-Covalent Functionalization of Carbon Nanotubes for siRNA Delivery , King Sun Siu

The Expression and Potential Significance of Human Kallikreins 6, 7, 8, 10, 13, and 14 in the Epithelium of Selected Odontogenic Cysts and Tumors of Variably Aggressive Biological Behaviour , Rebecca Woodford

Theses/Dissertations from 2013 2013

Targeted siRNA Delivery Methods for RNAi-Based Therapies , Di Chen

Elucidating the Role of Menin During Islet Cell Development in the Human Fetal Pancreas , Jessica L. Dubrick

Vascular Stem Cells in Diabetic Complications , Emily C. Keats

Theses/Dissertations from 2012 2012

Immunohistochemical Studies of Expression and Correlation of Osteopontin, CD44, and Integrin αVβ3 in Selected Benign and Malignant Salivary Gland Tumours , Tommy Fok

The role of non-canonical Wnt/planar cell polarity signalling in breast cancer progression , Connor D. MacMillan

Elucidating the Function of Transplanted Islets of Langerhans and Predicting Their Ability to Reverse Diabetes , Andrew R. Pepper

Role of ERK5 in Diabetic Vascular Complications , Yuexiu Wu

Regulation of NK cell-mediated tubular epithelial cell death and kidney ischemia-reperfusion injury by the NKR-P1B receptor and Clr-b , James Yip

Theses/Dissertations from 2011 2011

A Model System for Rapid Identification and Functional Testing of Genes Involved in Early Breast Cancer Progression , Lesley H. Souter

• Accessible Formats

Advanced Search

• Notify me via email or RSS
• Expert Gallery
• Online Journals
• eBook Collections
• Reports and Working Papers
• Conferences and Symposiums
• Electronic Theses and Dissertations
• Digitized Special Collections
• All Collections
• Disciplines

Author Corner

• Submit Thesis/Dissertation

Home | About | FAQ | My Account | Accessibility Statement | Privacy | Copyright

©1878 - 2016 Western University